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Side-by-side financial comparison of MarketAxess (MKTX) and Zai Lab Ltd (ZLAB). Click either name above to swap in a different company.

MarketAxess is the larger business by last-quarter revenue ($209.4M vs $127.1M, roughly 1.6× Zai Lab Ltd). On growth, Zai Lab Ltd posted the faster year-over-year revenue change (17.1% vs 3.5%). MarketAxess produced more free cash flow last quarter ($373.9M vs $-26.7M). Over the past eight quarters, Zai Lab Ltd's revenue compounded faster (20.8% CAGR vs -0.2%).

MarketAxess Holdings Inc. is an international financial technology company that operates an electronic trading platform for the institutional credit markets, and also provides market data and post-trade services. It enables institutional investors and broker-dealers to trade credit instruments, including corporate bonds, and other types of fixed income products.

Zai Lab Ltd is a global biopharmaceutical company focused on developing, manufacturing and commercializing innovative therapies for oncology, autoimmune disorders, infectious diseases and other unmet medical needs. It operates primarily in the Greater China region and partners with leading global biotech firms to expand access to life-saving treatments for underserved patient populations.

MKTX vs ZLAB — Head-to-Head

Bigger by revenue
MKTX
MKTX
1.6× larger
MKTX
$209.4M
$127.1M
ZLAB
Growing faster (revenue YoY)
ZLAB
ZLAB
+13.7% gap
ZLAB
17.1%
3.5%
MKTX
More free cash flow
MKTX
MKTX
$400.6M more FCF
MKTX
$373.9M
$-26.7M
ZLAB
Faster 2-yr revenue CAGR
ZLAB
ZLAB
Annualised
ZLAB
20.8%
-0.2%
MKTX

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
MKTX
MKTX
ZLAB
ZLAB
Revenue
$209.4M
$127.1M
Net Profit
$92.2M
Gross Margin
51.0%
Operating Margin
36.3%
-54.6%
Net Margin
44.0%
Revenue YoY
3.5%
17.1%
Net Profit YoY
41.6%
EPS (diluted)
$2.49
$-0.05

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
MKTX
MKTX
ZLAB
ZLAB
Q4 25
$209.4M
$127.1M
Q3 25
$208.8M
$115.4M
Q2 25
$219.5M
$109.1M
Q1 25
$208.6M
$105.7M
Q4 24
$202.4M
$108.5M
Q3 24
$206.7M
$101.8M
Q2 24
$197.7M
$100.1M
Q1 24
$210.3M
$87.1M
Net Profit
MKTX
MKTX
ZLAB
ZLAB
Q4 25
$92.2M
Q3 25
$68.2M
$-36.0M
Q2 25
$71.1M
$-40.7M
Q1 25
$15.1M
$-48.4M
Q4 24
$65.1M
Q3 24
$71.5M
$-41.7M
Q2 24
$64.9M
$-80.3M
Q1 24
$72.6M
$-53.5M
Gross Margin
MKTX
MKTX
ZLAB
ZLAB
Q4 25
51.0%
Q3 25
59.5%
Q2 25
60.6%
Q1 25
63.6%
Q4 24
61.5%
Q3 24
64.1%
Q2 24
64.9%
Q1 24
61.4%
Operating Margin
MKTX
MKTX
ZLAB
ZLAB
Q4 25
36.3%
-54.6%
Q3 25
41.0%
-42.3%
Q2 25
41.9%
-50.3%
Q1 25
42.4%
-53.3%
Q4 24
39.5%
-62.6%
Q3 24
42.1%
-66.6%
Q2 24
41.2%
-76.0%
Q1 24
44.0%
-80.7%
Net Margin
MKTX
MKTX
ZLAB
ZLAB
Q4 25
44.0%
Q3 25
32.6%
-31.2%
Q2 25
32.4%
-37.3%
Q1 25
7.2%
-45.8%
Q4 24
32.2%
Q3 24
34.6%
-40.9%
Q2 24
32.9%
-80.2%
Q1 24
34.5%
-61.4%
EPS (diluted)
MKTX
MKTX
ZLAB
ZLAB
Q4 25
$2.49
$-0.05
Q3 25
$1.84
$-0.03
Q2 25
$1.91
$-0.04
Q1 25
$0.40
$-0.04
Q4 24
$1.74
$-0.09
Q3 24
$1.90
$-0.04
Q2 24
$1.72
$-0.08
Q1 24
$1.92
$-0.05

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
MKTX
MKTX
ZLAB
ZLAB
Cash + ST InvestmentsLiquidity on hand
$519.7M
$689.6M
Total DebtLower is stronger
Stockholders' EquityBook value
$1.1B
$715.5M
Total Assets
$1.9B
$1.2B
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
MKTX
MKTX
ZLAB
ZLAB
Q4 25
$519.7M
$689.6M
Q3 25
$473.3M
$717.2M
Q2 25
$462.8M
$732.2M
Q1 25
$486.2M
$757.3M
Q4 24
$544.5M
$779.7M
Q3 24
$446.3M
$616.1M
Q2 24
$434.1M
$630.0M
Q1 24
$376.7M
$650.8M
Stockholders' Equity
MKTX
MKTX
ZLAB
ZLAB
Q4 25
$1.1B
$715.5M
Q3 25
$1.4B
$759.9M
Q2 25
$1.4B
$791.7M
Q1 25
$1.3B
$810.8M
Q4 24
$1.4B
$840.9M
Q3 24
$1.4B
$667.7M
Q2 24
$1.3B
$704.2M
Q1 24
$1.3B
$762.2M
Total Assets
MKTX
MKTX
ZLAB
ZLAB
Q4 25
$1.9B
$1.2B
Q3 25
$2.0B
$1.2B
Q2 25
$2.0B
$1.2B
Q1 25
$1.9B
$1.2B
Q4 24
$1.8B
$1.2B
Q3 24
$1.8B
$985.3M
Q2 24
$1.9B
$987.4M
Q1 24
$1.9B
$988.4M

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
MKTX
MKTX
ZLAB
ZLAB
Operating Cash FlowLast quarter
$382.1M
$-26.0M
Free Cash FlowOCF − Capex
$373.9M
$-26.7M
FCF MarginFCF / Revenue
178.6%
-21.0%
Capex IntensityCapex / Revenue
3.9%
0.5%
Cash ConversionOCF / Net Profit
4.14×
TTM Free Cash FlowTrailing 4 quarters
$592.8M
$-158.9M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
MKTX
MKTX
ZLAB
ZLAB
Q4 25
$382.1M
$-26.0M
Q3 25
$90.2M
$-32.0M
Q2 25
$103.7M
$-31.0M
Q1 25
$29.6M
$-61.7M
Q4 24
$385.2M
$-55.8M
Q3 24
$95.1M
$-26.8M
Q2 24
$118.8M
$-42.2M
Q1 24
$-4.9M
$-90.1M
Free Cash Flow
MKTX
MKTX
ZLAB
ZLAB
Q4 25
$373.9M
$-26.7M
Q3 25
$88.7M
$-35.0M
Q2 25
$102.5M
$-33.9M
Q1 25
$27.7M
$-63.2M
Q4 24
$375.3M
$-58.4M
Q3 24
$94.3M
$-28.2M
Q2 24
$111.2M
$-42.9M
Q1 24
$-6.1M
$-91.1M
FCF Margin
MKTX
MKTX
ZLAB
ZLAB
Q4 25
178.6%
-21.0%
Q3 25
42.5%
-30.4%
Q2 25
46.7%
-31.1%
Q1 25
13.3%
-59.9%
Q4 24
185.4%
-53.8%
Q3 24
45.6%
-27.7%
Q2 24
56.2%
-42.9%
Q1 24
-2.9%
-104.5%
Capex Intensity
MKTX
MKTX
ZLAB
ZLAB
Q4 25
3.9%
0.5%
Q3 25
0.7%
2.6%
Q2 25
0.5%
2.6%
Q1 25
0.9%
1.5%
Q4 24
4.9%
2.4%
Q3 24
0.4%
1.3%
Q2 24
3.9%
0.7%
Q1 24
0.6%
1.1%
Cash Conversion
MKTX
MKTX
ZLAB
ZLAB
Q4 25
4.14×
Q3 25
1.32×
Q2 25
1.46×
Q1 25
1.97×
Q4 24
5.91×
Q3 24
1.33×
Q2 24
1.83×
Q1 24
-0.07×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

MKTX
MKTX

Commission Revenue$181.3M87%
Information Services$13.5M6%
Post Trade Services$11.0M5%
Technology Services$3.6M2%

ZLAB
ZLAB

Zejula$56.0M44%
Other$21.9M17%
Nuzyra$16.0M13%
Optune$11.9M9%
XACDURO$10.7M8%
Qinlock$9.7M8%
AUGTYRO$836.0K1%

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