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Side-by-side financial comparison of MEDICAL PROPERTIES TRUST INC (MPW) and OPKO HEALTH, INC. (OPK). Click either name above to swap in a different company.

MEDICAL PROPERTIES TRUST INC is the larger business by last-quarter revenue ($270.3M vs $148.5M, roughly 1.8× OPKO HEALTH, INC.). MEDICAL PROPERTIES TRUST INC runs the higher net margin — 6.5% vs -21.1%, a 27.6% gap on every dollar of revenue. On growth, MEDICAL PROPERTIES TRUST INC posted the faster year-over-year revenue change (16.6% vs -19.2%). Over the past eight quarters, MEDICAL PROPERTIES TRUST INC's revenue compounded faster (-0.2% CAGR vs -7.5%).

Medical Properties Trust, Inc. (MPT) is an international real estate investment trust (REIT) based in Birmingham, Alabama that purchases and invests in healthcare facilities and for-profit healthcare holding companies, primarily in the United States and Europe. Their property acquisitions often come in the form of sale-leaseback agreements, in which the original property owner sells the property to MPT and becomes their tenant. MPT's tenants are generally subject to long-term triple net lease...

OPKO Health, Inc. is a medical test and medication company focused on diagnostics and pharmaceuticals. The company is a publicly traded company on NASDAQ and TASE under the symbol "OPK".

MPW vs OPK — Head-to-Head

Bigger by revenue
MPW
MPW
1.8× larger
MPW
$270.3M
$148.5M
OPK
Growing faster (revenue YoY)
MPW
MPW
+35.8% gap
MPW
16.6%
-19.2%
OPK
Higher net margin
MPW
MPW
27.6% more per $
MPW
6.5%
-21.1%
OPK
Faster 2-yr revenue CAGR
MPW
MPW
Annualised
MPW
-0.2%
-7.5%
OPK

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
MPW
MPW
OPK
OPK
Revenue
$270.3M
$148.5M
Net Profit
$17.6M
$-31.3M
Gross Margin
95.8%
43.1%
Operating Margin
9.7%
-25.8%
Net Margin
6.5%
-21.1%
Revenue YoY
16.6%
-19.2%
Net Profit YoY
104.3%
-322.8%
EPS (diluted)
$0.03
$-0.04

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
MPW
MPW
OPK
OPK
Q4 25
$270.3M
$148.5M
Q3 25
$237.5M
$151.7M
Q2 25
$240.4M
$156.8M
Q1 25
$223.8M
$150.0M
Q4 24
$231.8M
$183.6M
Q3 24
$225.8M
$173.6M
Q2 24
$266.6M
$182.2M
Q1 24
$271.3M
$173.7M
Net Profit
MPW
MPW
OPK
OPK
Q4 25
$17.6M
$-31.3M
Q3 25
$-77.7M
$21.6M
Q2 25
$-98.4M
$-148.4M
Q1 25
$-118.3M
$-67.6M
Q4 24
$-412.3M
$14.0M
Q3 24
$-801.2M
$24.9M
Q2 24
$-320.6M
$-10.3M
Q1 24
$-875.6M
$-81.8M
Gross Margin
MPW
MPW
OPK
OPK
Q4 25
95.8%
43.1%
Q3 25
32.9%
Q2 25
91.8%
31.5%
Q1 25
63.6%
28.4%
Q4 24
90.9%
46.1%
Q3 24
96.5%
23.1%
Q2 24
98.4%
28.4%
Q1 24
84.9%
24.2%
Operating Margin
MPW
MPW
OPK
OPK
Q4 25
9.7%
-25.8%
Q3 25
-28.0%
31.7%
Q2 25
-36.7%
-38.3%
Q1 25
-48.5%
-44.8%
Q4 24
-173.7%
-18.0%
Q3 24
-350.7%
8.2%
Q2 24
-114.5%
-33.9%
Q1 24
-318.6%
-41.2%
Net Margin
MPW
MPW
OPK
OPK
Q4 25
6.5%
-21.1%
Q3 25
-32.7%
14.3%
Q2 25
-40.9%
-94.7%
Q1 25
-52.8%
-45.1%
Q4 24
-177.8%
7.6%
Q3 24
-354.8%
14.3%
Q2 24
-120.3%
-5.7%
Q1 24
-322.7%
-47.1%
EPS (diluted)
MPW
MPW
OPK
OPK
Q4 25
$0.03
$-0.04
Q3 25
$-0.13
$0.03
Q2 25
$-0.16
$-0.19
Q1 25
$-0.20
$-0.10
Q4 24
$-0.68
$0.02
Q3 24
$-1.34
$0.03
Q2 24
$-0.54
$-0.01
Q1 24
$-1.46
$-0.12

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
MPW
MPW
OPK
OPK
Cash + ST InvestmentsLiquidity on hand
$540.9M
$364.4M
Total DebtLower is stronger
$9.7B
$344.0M
Stockholders' EquityBook value
$4.6B
$1.3B
Total Assets
$15.0B
$1.9B
Debt / EquityLower = less leverage
2.11×
0.27×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
MPW
MPW
OPK
OPK
Q4 25
$540.9M
$364.4M
Q3 25
$396.6M
$412.0M
Q2 25
$509.8M
$267.3M
Q1 25
$673.5M
$428.8M
Q4 24
$332.3M
$426.6M
Q3 24
$275.6M
$400.1M
Q2 24
$606.5M
$40.6M
Q1 24
$224.3M
$75.6M
Total Debt
MPW
MPW
OPK
OPK
Q4 25
$9.7B
$344.0M
Q3 25
$9.6B
$344.2M
Q2 25
$9.6B
$343.3M
Q1 25
$9.5B
$439.2M
Q4 24
$8.8B
$437.2M
Q3 24
$9.2B
$441.0M
Q2 24
$9.4B
$201.9M
Q1 24
$10.1B
$350.1M
Stockholders' Equity
MPW
MPW
OPK
OPK
Q4 25
$4.6B
$1.3B
Q3 25
$4.7B
$1.3B
Q2 25
$4.8B
$1.3B
Q1 25
$4.8B
$1.3B
Q4 24
$4.8B
$1.4B
Q3 24
$5.4B
$1.4B
Q2 24
$6.2B
$1.4B
Q1 24
$6.7B
$1.3B
Total Assets
MPW
MPW
OPK
OPK
Q4 25
$15.0B
$1.9B
Q3 25
$14.9B
$2.0B
Q2 25
$15.2B
$2.0B
Q1 25
$14.9B
$2.1B
Q4 24
$14.3B
$2.2B
Q3 24
$15.2B
$2.3B
Q2 24
$16.2B
$2.0B
Q1 24
$17.3B
$2.0B
Debt / Equity
MPW
MPW
OPK
OPK
Q4 25
2.11×
0.27×
Q3 25
2.06×
0.26×
Q2 25
2.00×
0.26×
Q1 25
1.99×
0.33×
Q4 24
1.83×
0.32×
Q3 24
1.69×
0.31×
Q2 24
1.51×
0.14×
Q1 24
1.51×
0.28×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
MPW
MPW
OPK
OPK
Operating Cash FlowLast quarter
$230.8M
$-25.9M
Free Cash FlowOCF − Capex
$-28.6M
FCF MarginFCF / Revenue
-19.3%
Capex IntensityCapex / Revenue
1.8%
Cash ConversionOCF / Net Profit
13.11×
TTM Free Cash FlowTrailing 4 quarters
$-190.8M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
MPW
MPW
OPK
OPK
Q4 25
$230.8M
$-25.9M
Q3 25
$18.6M
$-34.6M
Q2 25
$51.7M
$-83.4M
Q1 25
$384.0K
$-34.6M
Q4 24
$245.5M
$-44.4M
Q3 24
$59.2M
$-77.1M
Q2 24
$35.3M
$-26.4M
Q1 24
$74.3M
$-35.6M
Free Cash Flow
MPW
MPW
OPK
OPK
Q4 25
$-28.6M
Q3 25
$-37.8M
Q2 25
$-86.7M
Q1 25
$-37.7M
Q4 24
$-49.8M
Q3 24
$-85.0M
Q2 24
$-33.7M
Q1 24
$-40.0M
FCF Margin
MPW
MPW
OPK
OPK
Q4 25
-19.3%
Q3 25
-24.9%
Q2 25
-55.3%
Q1 25
-25.2%
Q4 24
-27.1%
Q3 24
-49.0%
Q2 24
-18.5%
Q1 24
-23.0%
Capex Intensity
MPW
MPW
OPK
OPK
Q4 25
1.8%
Q3 25
2.1%
Q2 25
2.1%
Q1 25
2.1%
Q4 24
2.9%
Q3 24
4.6%
Q2 24
4.0%
Q1 24
2.6%
Cash Conversion
MPW
MPW
OPK
OPK
Q4 25
13.11×
Q3 25
-1.60×
Q2 25
Q1 25
Q4 24
-3.17×
Q3 24
-3.10×
Q2 24
Q1 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

MPW
MPW

Segment breakdown not available.

OPK
OPK

Services$71.1M48%
Transfer Of Intellectual Property And Other$33.7M23%
IE$22.1M15%
Rayaldee$8.8M6%
Barda Agreement$6.8M5%
MX$6.3M4%

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