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Side-by-side financial comparison of Midland States Bancorp, Inc. (MSBI) and RHYTHM PHARMACEUTICALS, INC. (RYTM). Click either name above to swap in a different company.
Midland States Bancorp, Inc. is the larger business by last-quarter revenue ($79.5M vs $60.1M, roughly 1.3× RHYTHM PHARMACEUTICALS, INC.). Midland States Bancorp, Inc. runs the higher net margin — 23.2% vs -92.6%, a 115.8% gap on every dollar of revenue. Over the past eight quarters, RHYTHM PHARMACEUTICALS, INC.'s revenue compounded faster (43.8% CAGR vs -6.4%).
Rainier Bancorporation was the Seattle-based parent corporation of Rainier National Bank, a Washington state bank with branches throughout the state. Rainier traced its roots back to the National Bank of Commerce, which was founded by Richard Holyoke in 1889. The name Rainier National Bank was adopted in 1974. Rainier Bancorp expanded into Alaska with the purchase of Anchorage's People's Bank & Trust in 1983 and into Oregon with the purchase of Gresham's Mount Hood Security Bank in 1986, expa...
Rhythm Pharmaceuticals is a biopharmaceutical firm focused on developing and commercializing targeted therapies for rare genetic disorders causing severe unmanageable obesity, including POMC deficiency, LEPR deficiency, and Bardet-Biedl syndrome. It serves patients in North America and Europe who lack effective standard treatments for their chronic life-altering conditions.
MSBI vs RYTM — Head-to-Head
Income Statement — Q1 FY2026 vs Q1 FY2026
| Metric | | |
|---|---|---|
| Revenue | $79.5M | $60.1M |
| Net Profit | $18.5M | $-55.6M |
| Gross Margin | — | 88.1% |
| Operating Margin | — | -87.1% |
| Net Margin | 23.2% | -92.6% |
| Revenue YoY | — | 83.8% |
| Net Profit YoY | 739.3% | — |
| EPS (diluted) | $0.74 | $-0.83 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q1 26 | $79.5M | $60.1M | ||
| Q4 25 | $85.6M | $57.3M | ||
| Q3 25 | $81.1M | $51.3M | ||
| Q2 25 | $82.2M | $48.5M | ||
| Q1 25 | $76.1M | $32.7M | ||
| Q4 24 | $93.9M | $41.8M | ||
| Q3 24 | $92.7M | $33.3M | ||
| Q2 24 | $90.9M | $29.1M |
| Q1 26 | $18.5M | $-55.6M | ||
| Q4 25 | $-2.9M | $-47.5M | ||
| Q3 25 | $7.6M | $-52.9M | ||
| Q2 25 | $12.0M | $-46.6M | ||
| Q1 25 | $-141.0M | $-49.5M | ||
| Q4 24 | $-30.8M | $-43.3M | ||
| Q3 24 | $20.4M | $-43.6M | ||
| Q2 24 | $25.7M | $-32.3M |
| Q1 26 | — | 88.1% | ||
| Q4 25 | — | 91.6% | ||
| Q3 25 | — | 89.3% | ||
| Q2 25 | — | 88.6% | ||
| Q1 25 | — | 88.8% | ||
| Q4 24 | — | 90.9% | ||
| Q3 24 | — | 88.5% | ||
| Q2 24 | — | 89.9% |
| Q1 26 | — | -87.1% | ||
| Q4 25 | -5.5% | -82.2% | ||
| Q3 25 | 13.9% | -102.6% | ||
| Q2 25 | 18.1% | -93.4% | ||
| Q1 25 | -181.2% | -143.7% | ||
| Q4 24 | -66.5% | -98.6% | ||
| Q3 24 | 26.9% | -132.0% | ||
| Q2 24 | 35.0% | -139.2% |
| Q1 26 | 23.2% | -92.6% | ||
| Q4 25 | -4.9% | -83.0% | ||
| Q3 25 | 9.3% | -103.1% | ||
| Q2 25 | 14.6% | -96.1% | ||
| Q1 25 | -185.4% | -151.4% | ||
| Q4 24 | -52.5% | -103.6% | ||
| Q3 24 | 22.1% | -131.2% | ||
| Q2 24 | 28.3% | -110.9% |
| Q1 26 | $0.74 | $-0.83 | ||
| Q4 25 | $-0.22 | $-0.73 | ||
| Q3 25 | $0.24 | $-0.82 | ||
| Q2 25 | $0.44 | $-0.75 | ||
| Q1 25 | $-6.58 | $-0.81 | ||
| Q4 24 | $-1.49 | $-0.71 | ||
| Q3 24 | $0.83 | $-0.73 | ||
| Q2 24 | $1.06 | $-0.55 |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $89.4M | $340.6M |
| Total DebtLower is stronger | $33.2M | — |
| Stockholders' EquityBook value | $569.5M | $122.9M |
| Total Assets | $6.5B | $442.3M |
| Debt / EquityLower = less leverage | 0.06× | — |
8-quarter trend — quarters aligned by calendar period.
| Q1 26 | $89.4M | $340.6M | ||
| Q4 25 | $127.8M | $388.9M | ||
| Q3 25 | $166.1M | $416.1M | ||
| Q2 25 | $176.6M | $291.0M | ||
| Q1 25 | $102.0M | $314.5M | ||
| Q4 24 | $114.8M | $320.6M | ||
| Q3 24 | $121.9M | $298.4M | ||
| Q2 24 | $124.6M | $319.1M |
| Q1 26 | $33.2M | — | ||
| Q4 25 | — | — | ||
| Q3 25 | — | — | ||
| Q2 25 | — | — | ||
| Q1 25 | — | — | ||
| Q4 24 | — | — | ||
| Q3 24 | — | — | ||
| Q2 24 | — | — |
| Q1 26 | $569.5M | $122.9M | ||
| Q4 25 | $565.5M | $139.1M | ||
| Q3 25 | $584.0M | $148.8M | ||
| Q2 25 | $573.7M | $-11.9M | ||
| Q1 25 | $571.4M | $18.9M | ||
| Q4 24 | $710.8M | $21.7M | ||
| Q3 24 | $771.2M | $11.2M | ||
| Q2 24 | $736.8M | $39.3M |
| Q1 26 | $6.5B | $442.3M | ||
| Q4 25 | $6.5B | $480.2M | ||
| Q3 25 | $6.9B | $506.9M | ||
| Q2 25 | $7.1B | $372.7M | ||
| Q1 25 | $7.3B | $386.7M | ||
| Q4 24 | $7.5B | $392.3M | ||
| Q3 24 | $7.7B | $363.6M | ||
| Q2 24 | $7.7B | $381.8M |
| Q1 26 | 0.06× | — | ||
| Q4 25 | — | — | ||
| Q3 25 | — | — | ||
| Q2 25 | — | — | ||
| Q1 25 | — | — | ||
| Q4 24 | — | — | ||
| Q3 24 | — | — | ||
| Q2 24 | — | — |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
Revenue Breakdown by Segment
MSBI
| Net Interest Income | $57.4M | 72% |
| Noninterest Income | $22.1M | 28% |
RYTM
Segment breakdown not available.
