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Side-by-side financial comparison of MYRIAD GENETICS INC (MYGN) and Protagonist Therapeutics, Inc (PTGX). Click either name above to swap in a different company.
MYRIAD GENETICS INC is the larger business by last-quarter revenue ($209.8M vs $170.6M, roughly 1.2× Protagonist Therapeutics, Inc). On growth, Protagonist Therapeutics, Inc posted the faster year-over-year revenue change (184.4% vs -0.4%).
Myriad Genetics, Inc. is an American genetic testing and precision medicine company based in Salt Lake City, Utah, United States. Myriad employs a number of proprietary technologies that permit doctors and patients to understand the genetic basis of human disease and the role that genes play in the onset, progression and treatment of disease. This information is used to guide the development of new products that assess an individual's risk for developing disease later in life, identify a pati...
Protagonist Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on discovering and developing novel peptide-based targeted therapies for unmet medical needs, primarily covering gastrointestinal disorders, inflammatory diseases and rare disease indications. Its lead product candidates target inflammatory bowel disease and other chronic immune-related conditions, with operations spanning global R&D and partnership collaborations.
MYGN vs PTGX — Head-to-Head
Income Statement — Q4 FY2025 vs Q4 FY2024
| Metric | | |
|---|---|---|
| Revenue | $209.8M | $170.6M |
| Net Profit | — | $131.7M |
| Gross Margin | 70.0% | — |
| Operating Margin | -2.7% | 74.3% |
| Net Margin | — | 77.2% |
| Revenue YoY | -0.4% | 184.4% |
| Net Profit YoY | — | 381.7% |
| EPS (diluted) | $-0.09 | $2.01 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q4 25 | $209.8M | — | ||
| Q3 25 | $205.7M | — | ||
| Q2 25 | $213.1M | — | ||
| Q1 25 | $195.9M | — | ||
| Q4 24 | $210.6M | $170.6M | ||
| Q3 24 | $213.3M | — | ||
| Q2 24 | $211.5M | — | ||
| Q1 24 | $202.2M | $255.0M |
| Q4 25 | — | — | ||
| Q3 25 | $-27.4M | — | ||
| Q2 25 | $-330.5M | — | ||
| Q1 25 | $-100.0K | — | ||
| Q4 24 | — | $131.7M | ||
| Q3 24 | $-22.1M | — | ||
| Q2 24 | $-36.7M | — | ||
| Q1 24 | $-26.0M | $207.3M |
| Q4 25 | 70.0% | — | ||
| Q3 25 | 69.9% | — | ||
| Q2 25 | 71.2% | — | ||
| Q1 25 | 68.5% | — | ||
| Q4 24 | 71.7% | — | ||
| Q3 24 | 70.2% | — | ||
| Q2 24 | 69.6% | — | ||
| Q1 24 | 68.1% | — |
| Q4 25 | -2.7% | — | ||
| Q3 25 | -11.3% | — | ||
| Q2 25 | -154.5% | — | ||
| Q1 25 | -14.8% | — | ||
| Q4 24 | -18.6% | 74.3% | ||
| Q3 24 | -9.4% | — | ||
| Q2 24 | -17.3% | — | ||
| Q1 24 | -13.8% | 80.9% |
| Q4 25 | — | — | ||
| Q3 25 | -13.3% | — | ||
| Q2 25 | -155.1% | — | ||
| Q1 25 | -0.1% | — | ||
| Q4 24 | — | 77.2% | ||
| Q3 24 | -10.4% | — | ||
| Q2 24 | -17.4% | — | ||
| Q1 24 | -12.9% | 81.3% |
| Q4 25 | $-0.09 | — | ||
| Q3 25 | $-0.29 | — | ||
| Q2 25 | $-3.57 | — | ||
| Q1 25 | $0.00 | — | ||
| Q4 24 | $-0.47 | $2.01 | ||
| Q3 24 | $-0.24 | — | ||
| Q2 24 | $-0.41 | — | ||
| Q1 24 | $-0.29 | $3.26 |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $149.6M | $418.9M |
| Total DebtLower is stronger | $119.9M | — |
| Stockholders' EquityBook value | $368.0M | $675.3M |
| Total Assets | $706.6M | $744.7M |
| Debt / EquityLower = less leverage | 0.33× | — |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $149.6M | — | ||
| Q3 25 | $145.4M | — | ||
| Q2 25 | $74.4M | — | ||
| Q1 25 | $91.8M | — | ||
| Q4 24 | $102.4M | $418.9M | ||
| Q3 24 | $99.9M | — | ||
| Q2 24 | $97.3M | — | ||
| Q1 24 | $104.3M | $322.6M |
| Q4 25 | $119.9M | — | ||
| Q3 25 | $119.5M | — | ||
| Q2 25 | — | — | ||
| Q1 25 | — | — | ||
| Q4 24 | — | — | ||
| Q3 24 | — | — | ||
| Q2 24 | — | — | ||
| Q1 24 | — | — |
| Q4 25 | $368.0M | — | ||
| Q3 25 | $372.8M | — | ||
| Q2 25 | $388.1M | — | ||
| Q1 25 | $704.9M | — | ||
| Q4 24 | $701.1M | $675.3M | ||
| Q3 24 | $731.7M | — | ||
| Q2 24 | $740.5M | — | ||
| Q1 24 | $760.0M | $560.4M |
| Q4 25 | $706.6M | — | ||
| Q3 25 | $728.1M | — | ||
| Q2 25 | $677.3M | — | ||
| Q1 25 | $1.0B | — | ||
| Q4 24 | $1.0B | $744.7M | ||
| Q3 24 | $1.1B | — | ||
| Q2 24 | $1.1B | — | ||
| Q1 24 | $1.1B | $629.3M |
| Q4 25 | 0.33× | — | ||
| Q3 25 | 0.32× | — | ||
| Q2 25 | — | — | ||
| Q1 25 | — | — | ||
| Q4 24 | — | — | ||
| Q3 24 | — | — | ||
| Q2 24 | — | — | ||
| Q1 24 | — | — |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | $10.6M | $184.2M |
| Free Cash FlowOCF − Capex | — | $182.8M |
| FCF MarginFCF / Revenue | — | 107.1% |
| Capex IntensityCapex / Revenue | — | 0.8% |
| Cash ConversionOCF / Net Profit | — | 1.40× |
| TTM Free Cash FlowTrailing 4 quarters | — | $101.7M |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $10.6M | — | ||
| Q3 25 | $21.1M | — | ||
| Q2 25 | $-13.6M | — | ||
| Q1 25 | $-16.3M | — | ||
| Q4 24 | $6.6M | $184.2M | ||
| Q3 24 | $700.0K | — | ||
| Q2 24 | $2.6M | — | ||
| Q1 24 | $-18.6M | $-27.4M |
| Q4 25 | — | — | ||
| Q3 25 | — | — | ||
| Q2 25 | — | — | ||
| Q1 25 | — | — | ||
| Q4 24 | — | $182.8M | ||
| Q3 24 | — | — | ||
| Q2 24 | — | — | ||
| Q1 24 | — | $-27.7M |
| Q4 25 | — | — | ||
| Q3 25 | — | — | ||
| Q2 25 | — | — | ||
| Q1 25 | — | — | ||
| Q4 24 | — | 107.1% | ||
| Q3 24 | — | — | ||
| Q2 24 | — | — | ||
| Q1 24 | — | -10.9% |
| Q4 25 | — | — | ||
| Q3 25 | — | — | ||
| Q2 25 | — | — | ||
| Q1 25 | — | — | ||
| Q4 24 | — | 0.8% | ||
| Q3 24 | — | — | ||
| Q2 24 | — | — | ||
| Q1 24 | — | 0.1% |
| Q4 25 | — | — | ||
| Q3 25 | — | — | ||
| Q2 25 | — | — | ||
| Q1 25 | — | — | ||
| Q4 24 | — | 1.40× | ||
| Q3 24 | — | — | ||
| Q2 24 | — | — | ||
| Q1 24 | — | -0.13× |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
