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Side-by-side financial comparison of Niagen Bioscience, Inc. (NAGE) and Usio, Inc. (USIO). Click either name above to swap in a different company.

Niagen Bioscience, Inc. is the larger business by last-quarter revenue ($33.8M vs $22.2M, roughly 1.5× Usio, Inc.). Niagen Bioscience, Inc. runs the higher net margin — 12.2% vs -6.7%, a 18.9% gap on every dollar of revenue. On growth, Niagen Bioscience, Inc. posted the faster year-over-year revenue change (16.2% vs 8.2%). Over the past eight quarters, Niagen Bioscience, Inc.'s revenue compounded faster (23.6% CAGR vs 3.0%).

Niagen Bioscience, formerly ChromaDex, is a bioscience сompany based in Los Angeles, California founded in 1999. The company operates in multiple sectors including reference standards, dietary supplements, and ingredient technology. Niagen Bioscience is publicly traded on the NASDAQ.

Usio, Inc. is an American financial technology company headquartered in San Antonio, Texas. It provides integrated electronic payment services, including ACH processing, credit card and debit card acceptance, payment facilitation for software platforms, prepaid card issuing and a document print and mail operation.

NAGE vs USIO — Head-to-Head

Bigger by revenue
NAGE
NAGE
1.5× larger
NAGE
$33.8M
$22.2M
USIO
Growing faster (revenue YoY)
NAGE
NAGE
+8.0% gap
NAGE
16.2%
8.2%
USIO
Higher net margin
NAGE
NAGE
18.9% more per $
NAGE
12.2%
-6.7%
USIO
Faster 2-yr revenue CAGR
NAGE
NAGE
Annualised
NAGE
23.6%
3.0%
USIO

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
NAGE
NAGE
USIO
USIO
Revenue
$33.8M
$22.2M
Net Profit
$4.1M
$-1.5M
Gross Margin
64.1%
21.9%
Operating Margin
12.1%
-5.7%
Net Margin
12.2%
-6.7%
Revenue YoY
16.2%
8.2%
Net Profit YoY
-42.4%
-337.8%
EPS (diluted)
$0.05
$-0.05

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
NAGE
NAGE
USIO
USIO
Q4 25
$33.8M
$22.2M
Q3 25
$34.0M
$21.2M
Q2 25
$31.1M
$20.0M
Q1 25
$30.5M
$22.0M
Q4 24
$29.1M
$20.6M
Q3 24
$25.6M
$21.3M
Q2 24
$22.7M
$20.1M
Q1 24
$22.2M
$21.0M
Net Profit
NAGE
NAGE
USIO
USIO
Q4 25
$4.1M
$-1.5M
Q3 25
$4.6M
$-415.1K
Q2 25
$3.6M
$-366.7K
Q1 25
$5.1M
$-235.0K
Q4 24
$7.2M
$628.9K
Q3 24
$1.9M
$2.9M
Q2 24
$-15.0K
$75.5K
Q1 24
$-492.0K
$-250.2K
Gross Margin
NAGE
NAGE
USIO
USIO
Q4 25
64.1%
21.9%
Q3 25
64.5%
23.0%
Q2 25
65.0%
25.8%
Q1 25
63.4%
21.9%
Q4 24
62.5%
24.6%
Q3 24
63.5%
23.0%
Q2 24
60.2%
23.9%
Q1 24
60.7%
23.1%
Operating Margin
NAGE
NAGE
USIO
USIO
Q4 25
12.1%
-5.7%
Q3 25
12.5%
-2.2%
Q2 25
10.2%
-2.0%
Q1 25
15.7%
-1.1%
Q4 24
24.4%
-2.9%
Q3 24
6.3%
-1.8%
Q2 24
-1.1%
-1.0%
Q1 24
-3.3%
-1.3%
Net Margin
NAGE
NAGE
USIO
USIO
Q4 25
12.2%
-6.7%
Q3 25
13.5%
-2.0%
Q2 25
11.6%
-1.8%
Q1 25
16.6%
-1.1%
Q4 24
24.6%
3.1%
Q3 24
7.3%
13.4%
Q2 24
-0.1%
0.4%
Q1 24
-2.2%
-1.2%
EPS (diluted)
NAGE
NAGE
USIO
USIO
Q4 25
$0.05
$-0.05
Q3 25
$0.05
$-0.02
Q2 25
$0.04
$-0.01
Q1 25
$0.06
$-0.01
Q4 24
$0.10
$0.03
Q3 24
$0.02
$0.10
Q2 24
$0.00
$0.00
Q1 24
$-0.01
$-0.01

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
NAGE
NAGE
USIO
USIO
Cash + ST InvestmentsLiquidity on hand
$7.4M
Total DebtLower is stronger
$1.4M
Stockholders' EquityBook value
$76.5M
$17.9M
Total Assets
$106.4M
$134.9M
Debt / EquityLower = less leverage
0.08×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
NAGE
NAGE
USIO
USIO
Q4 25
$7.4M
Q3 25
$64.1M
$7.7M
Q2 25
$60.3M
$8.1M
Q1 25
$55.5M
$8.7M
Q4 24
$44.5M
$8.1M
Q3 24
$32.2M
$8.4M
Q2 24
$27.7M
$7.2M
Q1 24
$27.4M
$7.1M
Total Debt
NAGE
NAGE
USIO
USIO
Q4 25
$1.4M
Q3 25
$836.7K
Q2 25
$647.1K
Q1 25
$683.3K
Q4 24
$719.4K
Q3 24
$562.9K
Q2 24
$597.2K
Q1 24
$630.9K
Stockholders' Equity
NAGE
NAGE
USIO
USIO
Q4 25
$76.5M
$17.9M
Q3 25
$70.7M
$18.7M
Q2 25
$64.2M
$18.7M
Q1 25
$55.3M
$19.0M
Q4 24
$46.1M
$19.2M
Q3 24
$34.4M
$18.9M
Q2 24
$30.7M
$15.7M
Q1 24
$29.0M
$15.3M
Total Assets
NAGE
NAGE
USIO
USIO
Q4 25
$106.4M
$134.9M
Q3 25
$98.1M
$99.4M
Q2 25
$91.5M
$108.4M
Q1 25
$81.3M
$109.6M
Q4 24
$68.3M
$107.2M
Q3 24
$56.5M
$114.6M
Q2 24
$54.0M
$108.8M
Q1 24
$54.1M
$99.1M
Debt / Equity
NAGE
NAGE
USIO
USIO
Q4 25
0.08×
Q3 25
0.04×
Q2 25
0.03×
Q1 25
0.04×
Q4 24
0.04×
Q3 24
0.03×
Q2 24
0.04×
Q1 24
0.04×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
NAGE
NAGE
USIO
USIO
Operating Cash FlowLast quarter
$679.0K
$1.5M
Free Cash FlowOCF − Capex
$1.1M
FCF MarginFCF / Revenue
4.8%
Capex IntensityCapex / Revenue
2.0%
Cash ConversionOCF / Net Profit
0.16×
TTM Free Cash FlowTrailing 4 quarters
$1.7M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
NAGE
NAGE
USIO
USIO
Q4 25
$679.0K
$1.5M
Q3 25
$3.7M
$303.8K
Q2 25
$1.3M
$-263.9K
Q1 25
$7.9M
$1.4M
Q4 24
$8.6M
$2.9M
Q3 24
$3.5M
$1.4M
Q2 24
$-264.0K
$369.1K
Q1 24
$295.0K
$88.7K
Free Cash Flow
NAGE
NAGE
USIO
USIO
Q4 25
$1.1M
Q3 25
$85.2K
Q2 25
$-503.2K
Q1 25
$1.1M
Q4 24
$2.7M
Q3 24
$1.4M
Q2 24
$246.3K
Q1 24
$-88.1K
FCF Margin
NAGE
NAGE
USIO
USIO
Q4 25
4.8%
Q3 25
0.4%
Q2 25
-2.5%
Q1 25
4.8%
Q4 24
13.1%
Q3 24
6.4%
Q2 24
1.2%
Q1 24
-0.4%
Capex Intensity
NAGE
NAGE
USIO
USIO
Q4 25
2.0%
Q3 25
1.0%
Q2 25
1.2%
Q1 25
1.4%
Q4 24
1.0%
Q3 24
0.3%
Q2 24
0.6%
Q1 24
0.8%
Cash Conversion
NAGE
NAGE
USIO
USIO
Q4 25
0.16×
Q3 25
0.81×
Q2 25
0.35×
Q1 25
1.56×
Q4 24
1.20×
4.61×
Q3 24
1.86×
0.50×
Q2 24
4.89×
Q1 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

NAGE
NAGE

TRUNIAGEN Consumer Product$27.5M81%
Ingredients Segment$5.7M17%
Other$694.0K2%

USIO
USIO

Credit Card Revenue$7.7M35%
ACH And Complementary Service Revenue$6.1M28%
Output Solutions$5.4M24%
Prepaid Card Services Revenue$2.6M12%

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