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Side-by-side financial comparison of NEOGENOMICS INC (NEO) and Protagonist Therapeutics, Inc (PTGX). Click either name above to swap in a different company.

NEOGENOMICS INC is the larger business by last-quarter revenue ($186.7M vs $170.6M, roughly 1.1× Protagonist Therapeutics, Inc). Protagonist Therapeutics, Inc runs the higher net margin — 77.2% vs -57.9%, a 135.0% gap on every dollar of revenue. On growth, Protagonist Therapeutics, Inc posted the faster year-over-year revenue change (184.4% vs 11.1%).

NeoGenomics Laboratories, Inc., also known as NeoGenomics or Neo, is an American CLIA-certified clinical laboratory, pharma services and information services company that specializes in cancer genetics diagnostic testing. The company's testing services include cytogenetics, fluorescence in situ hybridization (FISH), flow cytometry, immunohistochemistry, anatomic pathology, and molecular genetics.

Protagonist Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on discovering and developing novel peptide-based targeted therapies for unmet medical needs, primarily covering gastrointestinal disorders, inflammatory diseases and rare disease indications. Its lead product candidates target inflammatory bowel disease and other chronic immune-related conditions, with operations spanning global R&D and partnership collaborations.

NEO vs PTGX — Head-to-Head

Bigger by revenue
NEO
NEO
1.1× larger
NEO
$186.7M
$170.6M
PTGX
Growing faster (revenue YoY)
PTGX
PTGX
+173.3% gap
PTGX
184.4%
11.1%
NEO
Higher net margin
PTGX
PTGX
135.0% more per $
PTGX
77.2%
-57.9%
NEO

Income Statement — Q1 FY2026 vs Q4 FY2024

Metric
NEO
NEO
PTGX
PTGX
Revenue
$186.7M
$170.6M
Net Profit
$-108.0M
$131.7M
Gross Margin
43.3%
Operating Margin
74.3%
Net Margin
-57.9%
77.2%
Revenue YoY
11.1%
184.4%
Net Profit YoY
42.0%
381.7%
EPS (diluted)
$-0.13
$2.01

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
NEO
NEO
PTGX
PTGX
Q1 26
$186.7M
Q4 25
$190.2M
Q3 25
$187.8M
Q2 25
$181.3M
Q1 25
$168.0M
Q4 24
$172.0M
$170.6M
Q3 24
$167.8M
Q2 24
$164.5M
Net Profit
NEO
NEO
PTGX
PTGX
Q1 26
$-108.0M
Q4 25
Q3 25
$-27.1M
Q2 25
$-45.1M
Q1 25
$-25.9M
Q4 24
$131.7M
Q3 24
$-17.7M
Q2 24
$-18.6M
Gross Margin
NEO
NEO
PTGX
PTGX
Q1 26
43.3%
Q4 25
43.8%
Q3 25
42.8%
Q2 25
42.6%
Q1 25
43.6%
Q4 24
44.9%
Q3 24
44.6%
Q2 24
44.1%
Operating Margin
NEO
NEO
PTGX
PTGX
Q1 26
Q4 25
-7.1%
Q3 25
-14.4%
Q2 25
-26.3%
Q1 25
-16.6%
Q4 24
-10.7%
74.3%
Q3 24
-12.6%
Q2 24
-13.3%
Net Margin
NEO
NEO
PTGX
PTGX
Q1 26
-57.9%
Q4 25
Q3 25
-14.4%
Q2 25
-24.9%
Q1 25
-15.4%
Q4 24
77.2%
Q3 24
-10.5%
Q2 24
-11.3%
EPS (diluted)
NEO
NEO
PTGX
PTGX
Q1 26
$-0.13
Q4 25
Q3 25
Q2 25
Q1 25
Q4 24
$2.01
Q3 24
Q2 24

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
NEO
NEO
PTGX
PTGX
Cash + ST InvestmentsLiquidity on hand
$146.1M
$418.9M
Total DebtLower is stronger
Stockholders' EquityBook value
$828.8M
$675.3M
Total Assets
$1.3B
$744.7M
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
NEO
NEO
PTGX
PTGX
Q1 26
$146.1M
Q4 25
$159.6M
Q3 25
$164.1M
Q2 25
$154.7M
Q1 25
$346.2M
Q4 24
$367.0M
$418.9M
Q3 24
$362.0M
Q2 24
$355.1M
Total Debt
NEO
NEO
PTGX
PTGX
Q1 26
Q4 25
$341.9M
Q3 25
Q2 25
Q1 25
Q4 24
$541.1M
Q3 24
Q2 24
Stockholders' Equity
NEO
NEO
PTGX
PTGX
Q1 26
$828.8M
Q4 25
$836.6M
Q3 25
$838.3M
Q2 25
$854.0M
Q1 25
$888.3M
Q4 24
$902.3M
$675.3M
Q3 24
$908.2M
Q2 24
$915.9M
Total Assets
NEO
NEO
PTGX
PTGX
Q1 26
$1.3B
Q4 25
$1.4B
Q3 25
$1.4B
Q2 25
$1.4B
Q1 25
$1.6B
Q4 24
$1.6B
$744.7M
Q3 24
$1.6B
Q2 24
$1.6B
Debt / Equity
NEO
NEO
PTGX
PTGX
Q1 26
Q4 25
0.41×
Q3 25
Q2 25
Q1 25
Q4 24
0.60×
Q3 24
Q2 24

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
NEO
NEO
PTGX
PTGX
Operating Cash FlowLast quarter
$-8.1M
$184.2M
Free Cash FlowOCF − Capex
$182.8M
FCF MarginFCF / Revenue
107.1%
Capex IntensityCapex / Revenue
0.8%
Cash ConversionOCF / Net Profit
1.40×
TTM Free Cash FlowTrailing 4 quarters
$101.7M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
NEO
NEO
PTGX
PTGX
Q1 26
$-8.1M
Q4 25
$1.3M
Q3 25
$8.9M
Q2 25
$20.3M
Q1 25
$-25.3M
Q4 24
$9.8M
$184.2M
Q3 24
$9.2M
Q2 24
$13.9M
Free Cash Flow
NEO
NEO
PTGX
PTGX
Q1 26
Q4 25
$-6.5M
Q3 25
$570.0K
Q2 25
$14.0M
Q1 25
$-29.8M
Q4 24
$-1.8M
$182.8M
Q3 24
$-1.6M
Q2 24
$814.0K
FCF Margin
NEO
NEO
PTGX
PTGX
Q1 26
Q4 25
-3.4%
Q3 25
0.3%
Q2 25
7.7%
Q1 25
-17.8%
Q4 24
-1.0%
107.1%
Q3 24
-0.9%
Q2 24
0.5%
Capex Intensity
NEO
NEO
PTGX
PTGX
Q1 26
Q4 25
4.1%
Q3 25
4.4%
Q2 25
3.5%
Q1 25
2.7%
Q4 24
6.7%
0.8%
Q3 24
6.4%
Q2 24
8.0%
Cash Conversion
NEO
NEO
PTGX
PTGX
Q1 26
Q4 25
Q3 25
Q2 25
Q1 25
Q4 24
1.40×
Q3 24
Q2 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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