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Side-by-side financial comparison of Neuphoria Therapeutics Inc. (NEUP) and Usio, Inc. (USIO). Click either name above to swap in a different company.

Usio, Inc. is the larger business by last-quarter revenue ($22.2M vs $15.0M, roughly 1.5× Neuphoria Therapeutics Inc.). Neuphoria Therapeutics Inc. runs the higher net margin — 75.1% vs -6.7%, a 81.8% gap on every dollar of revenue.

Neuphoria Therapeutics Inc is a clinical-stage biopharmaceutical company focused on researching and developing innovative targeted therapies for unmet medical needs in neurological and psychiatric conditions, including anxiety, treatment-resistant depression, and other central nervous system disorders. Its core R&D efforts prioritize delivering safer, more effective treatment options for patient groups with limited existing care alternatives.

Usio, Inc. is an American financial technology company headquartered in San Antonio, Texas. It provides integrated electronic payment services, including ACH processing, credit card and debit card acceptance, payment facilitation for software platforms, prepaid card issuing and a document print and mail operation.

NEUP vs USIO — Head-to-Head

Bigger by revenue
USIO
USIO
1.5× larger
USIO
$22.2M
$15.0M
NEUP
Higher net margin
NEUP
NEUP
81.8% more per $
NEUP
75.1%
-6.7%
USIO

Income Statement — Q3 FY2025 vs Q4 FY2025

Metric
NEUP
NEUP
USIO
USIO
Revenue
$15.0M
$22.2M
Net Profit
$11.3M
$-1.5M
Gross Margin
21.9%
Operating Margin
79.8%
-5.7%
Net Margin
75.1%
-6.7%
Revenue YoY
8.2%
Net Profit YoY
-337.8%
EPS (diluted)
$6.55
$-0.05

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
NEUP
NEUP
USIO
USIO
Q4 25
$22.2M
Q3 25
$21.2M
Q2 25
$20.0M
Q1 25
$15.0M
$22.0M
Q4 24
$20.6M
Q3 24
$21.3M
Q2 24
$20.1M
Q1 24
$21.0M
Net Profit
NEUP
NEUP
USIO
USIO
Q4 25
$-1.5M
Q3 25
$-415.1K
Q2 25
$-366.7K
Q1 25
$11.3M
$-235.0K
Q4 24
$628.9K
Q3 24
$2.9M
Q2 24
$75.5K
Q1 24
$-250.2K
Gross Margin
NEUP
NEUP
USIO
USIO
Q4 25
21.9%
Q3 25
23.0%
Q2 25
25.8%
Q1 25
21.9%
Q4 24
24.6%
Q3 24
23.0%
Q2 24
23.9%
Q1 24
23.1%
Operating Margin
NEUP
NEUP
USIO
USIO
Q4 25
-5.7%
Q3 25
-2.2%
Q2 25
-2.0%
Q1 25
79.8%
-1.1%
Q4 24
-2.9%
Q3 24
-1.8%
Q2 24
-1.0%
Q1 24
-1.3%
Net Margin
NEUP
NEUP
USIO
USIO
Q4 25
-6.7%
Q3 25
-2.0%
Q2 25
-1.8%
Q1 25
75.1%
-1.1%
Q4 24
3.1%
Q3 24
13.4%
Q2 24
0.4%
Q1 24
-1.2%
EPS (diluted)
NEUP
NEUP
USIO
USIO
Q4 25
$-0.05
Q3 25
$-0.02
Q2 25
$-0.01
Q1 25
$6.55
$-0.01
Q4 24
$0.03
Q3 24
$0.10
Q2 24
$0.00
Q1 24
$-0.01

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
NEUP
NEUP
USIO
USIO
Cash + ST InvestmentsLiquidity on hand
$17.0M
$7.4M
Total DebtLower is stronger
$1.4M
Stockholders' EquityBook value
$26.0M
$17.9M
Total Assets
$30.7M
$134.9M
Debt / EquityLower = less leverage
0.08×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
NEUP
NEUP
USIO
USIO
Q4 25
$7.4M
Q3 25
$7.7M
Q2 25
$8.1M
Q1 25
$17.0M
$8.7M
Q4 24
$8.1M
Q3 24
$8.4M
Q2 24
$7.2M
Q1 24
$7.1M
Total Debt
NEUP
NEUP
USIO
USIO
Q4 25
$1.4M
Q3 25
$836.7K
Q2 25
$647.1K
Q1 25
$683.3K
Q4 24
$719.4K
Q3 24
$562.9K
Q2 24
$597.2K
Q1 24
$630.9K
Stockholders' Equity
NEUP
NEUP
USIO
USIO
Q4 25
$17.9M
Q3 25
$18.7M
Q2 25
$18.7M
Q1 25
$26.0M
$19.0M
Q4 24
$19.2M
Q3 24
$18.9M
Q2 24
$15.7M
Q1 24
$15.3M
Total Assets
NEUP
NEUP
USIO
USIO
Q4 25
$134.9M
Q3 25
$99.4M
Q2 25
$108.4M
Q1 25
$30.7M
$109.6M
Q4 24
$107.2M
Q3 24
$114.6M
Q2 24
$108.8M
Q1 24
$99.1M
Debt / Equity
NEUP
NEUP
USIO
USIO
Q4 25
0.08×
Q3 25
0.04×
Q2 25
0.03×
Q1 25
0.04×
Q4 24
0.04×
Q3 24
0.03×
Q2 24
0.04×
Q1 24
0.04×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
NEUP
NEUP
USIO
USIO
Operating Cash FlowLast quarter
$11.5M
$1.5M
Free Cash FlowOCF − Capex
$1.1M
FCF MarginFCF / Revenue
4.8%
Capex IntensityCapex / Revenue
2.0%
Cash ConversionOCF / Net Profit
1.02×
TTM Free Cash FlowTrailing 4 quarters
$1.7M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
NEUP
NEUP
USIO
USIO
Q4 25
$1.5M
Q3 25
$303.8K
Q2 25
$-263.9K
Q1 25
$11.5M
$1.4M
Q4 24
$2.9M
Q3 24
$1.4M
Q2 24
$369.1K
Q1 24
$88.7K
Free Cash Flow
NEUP
NEUP
USIO
USIO
Q4 25
$1.1M
Q3 25
$85.2K
Q2 25
$-503.2K
Q1 25
$1.1M
Q4 24
$2.7M
Q3 24
$1.4M
Q2 24
$246.3K
Q1 24
$-88.1K
FCF Margin
NEUP
NEUP
USIO
USIO
Q4 25
4.8%
Q3 25
0.4%
Q2 25
-2.5%
Q1 25
4.8%
Q4 24
13.1%
Q3 24
6.4%
Q2 24
1.2%
Q1 24
-0.4%
Capex Intensity
NEUP
NEUP
USIO
USIO
Q4 25
2.0%
Q3 25
1.0%
Q2 25
1.2%
Q1 25
1.4%
Q4 24
1.0%
Q3 24
0.3%
Q2 24
0.6%
Q1 24
0.8%
Cash Conversion
NEUP
NEUP
USIO
USIO
Q4 25
Q3 25
Q2 25
Q1 25
1.02×
Q4 24
4.61×
Q3 24
0.50×
Q2 24
4.89×
Q1 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

NEUP
NEUP

Segment breakdown not available.

USIO
USIO

Credit Card Revenue$7.7M35%
ACH And Complementary Service Revenue$6.1M28%
Output Solutions$5.4M24%
Prepaid Card Services Revenue$2.6M12%

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