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Side-by-side financial comparison of NICOLET BANKSHARES INC (NIC) and OPKO HEALTH, INC. (OPK). Click either name above to swap in a different company.
OPKO HEALTH, INC. is the larger business by last-quarter revenue ($148.5M vs $104.0M, roughly 1.4× NICOLET BANKSHARES INC). NICOLET BANKSHARES INC runs the higher net margin — 38.8% vs -21.1%, a 59.8% gap on every dollar of revenue. On growth, NICOLET BANKSHARES INC posted the faster year-over-year revenue change (12.5% vs -19.2%). NICOLET BANKSHARES INC produced more free cash flow last quarter ($149.4M vs $-28.6M). Over the past eight quarters, NICOLET BANKSHARES INC's revenue compounded faster (12.5% CAGR vs -7.5%).
Nicolet Bankshares, Inc. is a U.S. regional bank holding company based in Green Bay, Wisconsin. They are the parent company of Nicolet National Bank, the second largest Wisconsin-based bank.
OPKO Health, Inc. is a medical test and medication company focused on diagnostics and pharmaceuticals. The company is a publicly traded company on NASDAQ and TASE under the symbol "OPK".
NIC vs OPK — Head-to-Head
Income Statement — Q4 FY2025 vs Q4 FY2025
| Metric | | |
|---|---|---|
| Revenue | $104.0M | $148.5M |
| Net Profit | $40.3M | $-31.3M |
| Gross Margin | — | 43.1% |
| Operating Margin | 48.3% | -25.8% |
| Net Margin | 38.8% | -21.1% |
| Revenue YoY | 12.5% | -19.2% |
| Net Profit YoY | 16.9% | -322.8% |
| EPS (diluted) | $2.63 | $-0.04 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q4 25 | $104.0M | $148.5M | ||
| Q3 25 | $102.9M | $151.7M | ||
| Q2 25 | $95.7M | $156.8M | ||
| Q1 25 | $89.4M | $150.0M | ||
| Q4 24 | $92.4M | $183.6M | ||
| Q3 24 | $90.7M | $173.6M | ||
| Q2 24 | $85.0M | $182.2M | ||
| Q1 24 | $82.2M | $173.7M |
| Q4 25 | $40.3M | $-31.3M | ||
| Q3 25 | $41.7M | $21.6M | ||
| Q2 25 | $36.0M | $-148.4M | ||
| Q1 25 | $32.6M | $-67.6M | ||
| Q4 24 | $34.5M | $14.0M | ||
| Q3 24 | $32.5M | $24.9M | ||
| Q2 24 | $29.3M | $-10.3M | ||
| Q1 24 | $27.8M | $-81.8M |
| Q4 25 | — | 43.1% | ||
| Q3 25 | — | 32.9% | ||
| Q2 25 | — | 31.5% | ||
| Q1 25 | — | 28.4% | ||
| Q4 24 | — | 46.1% | ||
| Q3 24 | — | 23.1% | ||
| Q2 24 | — | 28.4% | ||
| Q1 24 | — | 24.2% |
| Q4 25 | 48.3% | -25.8% | ||
| Q3 25 | 50.4% | 31.7% | ||
| Q2 25 | 46.8% | -38.3% | ||
| Q1 25 | 44.9% | -44.8% | ||
| Q4 24 | 46.8% | -18.0% | ||
| Q3 24 | 45.0% | 8.2% | ||
| Q2 24 | 43.3% | -33.9% | ||
| Q1 24 | 41.8% | -41.2% |
| Q4 25 | 38.8% | -21.1% | ||
| Q3 25 | 40.6% | 14.3% | ||
| Q2 25 | 37.6% | -94.7% | ||
| Q1 25 | 36.4% | -45.1% | ||
| Q4 24 | 37.3% | 7.6% | ||
| Q3 24 | 35.8% | 14.3% | ||
| Q2 24 | 34.5% | -5.7% | ||
| Q1 24 | 33.8% | -47.1% |
| Q4 25 | $2.63 | $-0.04 | ||
| Q3 25 | $2.73 | $0.03 | ||
| Q2 25 | $2.34 | $-0.19 | ||
| Q1 25 | $2.08 | $-0.10 | ||
| Q4 24 | $2.21 | $0.02 | ||
| Q3 24 | $2.10 | $0.03 | ||
| Q2 24 | $1.92 | $-0.01 | ||
| Q1 24 | $1.82 | $-0.12 |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | — | $364.4M |
| Total DebtLower is stronger | $134.9M | $344.0M |
| Stockholders' EquityBook value | $1.3B | $1.3B |
| Total Assets | $9.2B | $1.9B |
| Debt / EquityLower = less leverage | 0.11× | 0.27× |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | — | $364.4M | ||
| Q3 25 | — | $412.0M | ||
| Q2 25 | — | $267.3M | ||
| Q1 25 | — | $428.8M | ||
| Q4 24 | — | $426.6M | ||
| Q3 24 | — | $400.1M | ||
| Q2 24 | — | $40.6M | ||
| Q1 24 | — | $75.6M |
| Q4 25 | $134.9M | $344.0M | ||
| Q3 25 | $134.6M | $344.2M | ||
| Q2 25 | $134.3M | $343.3M | ||
| Q1 25 | $156.6M | $439.2M | ||
| Q4 24 | $161.4M | $437.2M | ||
| Q3 24 | $161.2M | $441.0M | ||
| Q2 24 | $162.4M | $201.9M | ||
| Q1 24 | $162.3M | $350.1M |
| Q4 25 | $1.3B | $1.3B | ||
| Q3 25 | $1.2B | $1.3B | ||
| Q2 25 | $1.2B | $1.3B | ||
| Q1 25 | $1.2B | $1.3B | ||
| Q4 24 | $1.2B | $1.4B | ||
| Q3 24 | $1.1B | $1.4B | ||
| Q2 24 | $1.1B | $1.4B | ||
| Q1 24 | $1.1B | $1.3B |
| Q4 25 | $9.2B | $1.9B | ||
| Q3 25 | $9.0B | $2.0B | ||
| Q2 25 | $8.9B | $2.0B | ||
| Q1 25 | $9.0B | $2.1B | ||
| Q4 24 | $8.8B | $2.2B | ||
| Q3 24 | $8.6B | $2.3B | ||
| Q2 24 | $8.6B | $2.0B | ||
| Q1 24 | $8.4B | $2.0B |
| Q4 25 | 0.11× | 0.27× | ||
| Q3 25 | 0.11× | 0.26× | ||
| Q2 25 | 0.11× | 0.26× | ||
| Q1 25 | 0.13× | 0.33× | ||
| Q4 24 | 0.14× | 0.32× | ||
| Q3 24 | 0.14× | 0.31× | ||
| Q2 24 | 0.15× | 0.14× | ||
| Q1 24 | 0.15× | 0.28× |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | $153.5M | $-25.9M |
| Free Cash FlowOCF − Capex | $149.4M | $-28.6M |
| FCF MarginFCF / Revenue | 143.7% | -19.3% |
| Capex IntensityCapex / Revenue | 3.9% | 1.8% |
| Cash ConversionOCF / Net Profit | 3.81× | — |
| TTM Free Cash FlowTrailing 4 quarters | $275.0M | $-190.8M |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $153.5M | $-25.9M | ||
| Q3 25 | $45.9M | $-34.6M | ||
| Q2 25 | $38.9M | $-83.4M | ||
| Q1 25 | $41.8M | $-34.6M | ||
| Q4 24 | $133.7M | $-44.4M | ||
| Q3 24 | $39.6M | $-77.1M | ||
| Q2 24 | $37.3M | $-26.4M | ||
| Q1 24 | $23.4M | $-35.6M |
| Q4 25 | $149.4M | $-28.6M | ||
| Q3 25 | $45.9M | $-37.8M | ||
| Q2 25 | $38.4M | $-86.7M | ||
| Q1 25 | $41.3M | $-37.7M | ||
| Q4 24 | $116.8M | $-49.8M | ||
| Q3 24 | $34.7M | $-85.0M | ||
| Q2 24 | $34.4M | $-33.7M | ||
| Q1 24 | $20.1M | $-40.0M |
| Q4 25 | 143.7% | -19.3% | ||
| Q3 25 | 44.6% | -24.9% | ||
| Q2 25 | 40.1% | -55.3% | ||
| Q1 25 | 46.2% | -25.2% | ||
| Q4 24 | 126.4% | -27.1% | ||
| Q3 24 | 38.3% | -49.0% | ||
| Q2 24 | 40.5% | -18.5% | ||
| Q1 24 | 24.4% | -23.0% |
| Q4 25 | 3.9% | 1.8% | ||
| Q3 25 | 0.0% | 2.1% | ||
| Q2 25 | 0.6% | 2.1% | ||
| Q1 25 | 0.5% | 2.1% | ||
| Q4 24 | 18.3% | 2.9% | ||
| Q3 24 | 5.4% | 4.6% | ||
| Q2 24 | 3.5% | 4.0% | ||
| Q1 24 | 4.0% | 2.6% |
| Q4 25 | 3.81× | — | ||
| Q3 25 | 1.10× | -1.60× | ||
| Q2 25 | 1.08× | — | ||
| Q1 25 | 1.28× | — | ||
| Q4 24 | 3.88× | -3.17× | ||
| Q3 24 | 1.22× | -3.10× | ||
| Q2 24 | 1.28× | — | ||
| Q1 24 | 0.84× | — |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
Revenue Breakdown by Segment
NIC
Segment breakdown not available.
OPK
| Services | $71.1M | 48% |
| Transfer Of Intellectual Property And Other | $33.7M | 23% |
| IE | $22.1M | 15% |
| Rayaldee | $8.8M | 6% |
| Barda Agreement | $6.8M | 5% |
| MX | $6.3M | 4% |
