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Side-by-side financial comparison of NEKTAR THERAPEUTICS (NKTR) and SYPRIS SOLUTIONS INC (SYPR). Click either name above to swap in a different company.

SYPRIS SOLUTIONS INC is the larger business by last-quarter revenue ($30.3M vs $21.8M, roughly 1.4× NEKTAR THERAPEUTICS). SYPRIS SOLUTIONS INC runs the higher net margin — -12.9% vs -165.4%, a 152.6% gap on every dollar of revenue. On growth, SYPRIS SOLUTIONS INC posted the faster year-over-year revenue change (-9.5% vs -25.3%). SYPRIS SOLUTIONS INC produced more free cash flow last quarter ($-1.5M vs $-65.0M). Over the past eight quarters, NEKTAR THERAPEUTICS's revenue compounded faster (0.4% CAGR vs -7.7%).

Nektar Therapeutics is an American biopharmaceutical company. The company was founded in 1990 and is based in San Francisco, California. The company develops new drug candidates by applying its proprietary PEGylation and advanced polymer conjugate technologies to modify chemical structure of substances, which improves drug characteristics like retention and solubility. It is a technology supplier to a number of pharmaceutical companies including Affymax, Amgen, Merck, Pfizer and UCB Pharma, e...

Sypris Solutions Inc. is a U.S.-headquartered provider of highly engineered components and specialized technical services, primarily serving aerospace, defense, automotive and commercial industrial markets. It delivers custom manufacturing, performance testing, and value-added engineering support for mission-critical systems and parts for global enterprise clients.

NKTR vs SYPR — Head-to-Head

Bigger by revenue
SYPR
SYPR
1.4× larger
SYPR
$30.3M
$21.8M
NKTR
Growing faster (revenue YoY)
SYPR
SYPR
+15.8% gap
SYPR
-9.5%
-25.3%
NKTR
Higher net margin
SYPR
SYPR
152.6% more per $
SYPR
-12.9%
-165.4%
NKTR
More free cash flow
SYPR
SYPR
$63.5M more FCF
SYPR
$-1.5M
$-65.0M
NKTR
Faster 2-yr revenue CAGR
NKTR
NKTR
Annualised
NKTR
0.4%
-7.7%
SYPR

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
NKTR
NKTR
SYPR
SYPR
Revenue
$21.8M
$30.3M
Net Profit
$-36.1M
$-3.9M
Gross Margin
4.6%
Operating Margin
-126.9%
-10.9%
Net Margin
-165.4%
-12.9%
Revenue YoY
-25.3%
-9.5%
Net Profit YoY
-596.9%
-2992.6%
EPS (diluted)
$-4.67
$-0.17

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
NKTR
NKTR
SYPR
SYPR
Q4 25
$21.8M
$30.3M
Q3 25
$11.8M
$28.7M
Q2 25
$11.2M
$31.4M
Q1 25
$10.5M
$29.5M
Q4 24
$29.2M
$33.4M
Q3 24
$24.1M
$35.7M
Q2 24
$23.5M
$35.5M
Q1 24
$21.6M
$35.6M
Net Profit
NKTR
NKTR
SYPR
SYPR
Q4 25
$-36.1M
$-3.9M
Q3 25
$-35.5M
$517.0K
Q2 25
$-41.6M
$-2.1M
Q1 25
$-50.9M
$-899.0K
Q4 24
$7.3M
$135.0K
Q3 24
$-37.1M
$390.0K
Q2 24
$-52.4M
$16.0K
Q1 24
$-36.8M
$-2.2M
Gross Margin
NKTR
NKTR
SYPR
SYPR
Q4 25
4.6%
Q3 25
7.2%
Q2 25
8.2%
Q1 25
11.4%
Q4 24
72.7%
16.1%
Q3 24
81.6%
16.8%
Q2 24
58.5%
15.9%
Q1 24
60.6%
8.1%
Operating Margin
NKTR
NKTR
SYPR
SYPR
Q4 25
-126.9%
-10.9%
Q3 25
-268.6%
-6.1%
Q2 25
-324.2%
-4.6%
Q1 25
-425.8%
-0.4%
Q4 24
49.2%
3.9%
Q3 24
-142.4%
4.8%
Q2 24
-211.9%
3.6%
Q1 24
-163.7%
-3.9%
Net Margin
NKTR
NKTR
SYPR
SYPR
Q4 25
-165.4%
-12.9%
Q3 25
-301.3%
1.8%
Q2 25
-372.2%
-6.5%
Q1 25
-486.4%
-3.0%
Q4 24
24.9%
0.4%
Q3 24
-153.6%
1.1%
Q2 24
-222.9%
0.0%
Q1 24
-170.1%
-6.2%
EPS (diluted)
NKTR
NKTR
SYPR
SYPR
Q4 25
$-4.67
$-0.17
Q3 25
$-1.87
$0.02
Q2 25
$-2.95
$-0.09
Q1 25
$-0.24
$-0.04
Q4 24
$-2.07
$0.00
Q3 24
$-2.66
$0.02
Q2 24
$-3.76
$0.00
Q1 24
$-0.19
$-0.10

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
NKTR
NKTR
SYPR
SYPR
Cash + ST InvestmentsLiquidity on hand
$15.1M
Total DebtLower is stronger
Stockholders' EquityBook value
$89.8M
$17.8M
Total Assets
$280.4M
$107.8M
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
NKTR
NKTR
SYPR
SYPR
Q4 25
$15.1M
Q3 25
$41.0M
Q2 25
$43.0M
Q1 25
$38.9M
Q4 24
$44.3M
Q3 24
$30.1M
Q2 24
$27.9M
Q1 24
$48.6M
Stockholders' Equity
NKTR
NKTR
SYPR
SYPR
Q4 25
$89.8M
$17.8M
Q3 25
$85.1M
$20.0M
Q2 25
$-24.2M
$18.7M
Q1 25
$13.7M
$19.0M
Q4 24
$60.7M
$19.6M
Q3 24
$48.9M
$18.2M
Q2 24
$79.7M
$19.0M
Q1 24
$126.7M
$20.8M
Total Assets
NKTR
NKTR
SYPR
SYPR
Q4 25
$280.4M
$107.8M
Q3 25
$301.3M
$112.5M
Q2 25
$207.5M
$105.8M
Q1 25
$256.2M
$110.2M
Q4 24
$303.9M
$119.4M
Q3 24
$308.0M
$121.6M
Q2 24
$343.3M
$124.2M
Q1 24
$396.0M
$129.0M

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
NKTR
NKTR
SYPR
SYPR
Operating Cash FlowLast quarter
$-65.0M
$-1.1M
Free Cash FlowOCF − Capex
$-65.0M
$-1.5M
FCF MarginFCF / Revenue
-298.0%
-5.0%
Capex IntensityCapex / Revenue
0.1%
1.3%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$-208.7M
$-6.5M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
NKTR
NKTR
SYPR
SYPR
Q4 25
$-65.0M
$-1.1M
Q3 25
$-48.8M
$-178.0K
Q2 25
$-45.7M
$1.1M
Q1 25
$-49.1M
$-5.5M
Q4 24
$-46.2M
$2.3M
Q3 24
$-43.9M
$-4.8M
Q2 24
$-37.7M
$6.2M
Q1 24
$-47.9M
$-1.7M
Free Cash Flow
NKTR
NKTR
SYPR
SYPR
Q4 25
$-65.0M
$-1.5M
Q3 25
$-48.9M
$-390.0K
Q2 25
$-45.8M
$941.0K
Q1 25
$-49.1M
$-5.5M
Q4 24
$-46.6M
$1.9M
Q3 24
$-44.6M
$-4.9M
Q2 24
$-37.9M
$6.0M
Q1 24
$-48.0M
$-2.0M
FCF Margin
NKTR
NKTR
SYPR
SYPR
Q4 25
-298.0%
-5.0%
Q3 25
-414.5%
-1.4%
Q2 25
-409.6%
3.0%
Q1 25
-469.0%
-18.8%
Q4 24
-159.9%
5.7%
Q3 24
-184.9%
-13.8%
Q2 24
-161.3%
16.8%
Q1 24
-222.0%
-5.7%
Capex Intensity
NKTR
NKTR
SYPR
SYPR
Q4 25
0.1%
1.3%
Q3 25
1.0%
0.7%
Q2 25
0.3%
0.5%
Q1 25
0.0%
0.0%
Q4 24
1.6%
1.2%
Q3 24
2.8%
0.4%
Q2 24
0.8%
0.5%
Q1 24
0.7%
0.9%
Cash Conversion
NKTR
NKTR
SYPR
SYPR
Q4 25
Q3 25
-0.34×
Q2 25
Q1 25
Q4 24
-6.36×
17.13×
Q3 24
-12.21×
Q2 24
385.25×
Q1 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

NKTR
NKTR

Segment breakdown not available.

SYPR
SYPR

Sypris Electronics$17.7M59%
Transferred At Point In Time$12.5M41%

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