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Side-by-side financial comparison of OCULAR THERAPEUTIX, INC (OCUL) and Usio, Inc. (USIO). Click either name above to swap in a different company.

Usio, Inc. is the larger business by last-quarter revenue ($22.2M vs $13.3M, roughly 1.7× OCULAR THERAPEUTIX, INC). Usio, Inc. runs the higher net margin — -6.7% vs -488.0%, a 481.2% gap on every dollar of revenue. On growth, Usio, Inc. posted the faster year-over-year revenue change (8.2% vs -22.4%). Usio, Inc. produced more free cash flow last quarter ($1.1M vs $-57.1M). Over the past eight quarters, Usio, Inc.'s revenue compounded faster (3.0% CAGR vs -5.3%).

Ocular Therapeutix, Inc. is a biopharmaceutical firm specializing in developing and commercializing innovative ophthalmic therapies. Its products treat acute and chronic eye conditions including post-surgical pain, glaucoma, and dry eye, serving patients and ophthalmology providers primarily across the U.S. and select global markets.

Usio, Inc. is an American financial technology company headquartered in San Antonio, Texas. It provides integrated electronic payment services, including ACH processing, credit card and debit card acceptance, payment facilitation for software platforms, prepaid card issuing and a document print and mail operation.

OCUL vs USIO — Head-to-Head

Bigger by revenue
USIO
USIO
1.7× larger
USIO
$22.2M
$13.3M
OCUL
Growing faster (revenue YoY)
USIO
USIO
+30.6% gap
USIO
8.2%
-22.4%
OCUL
Higher net margin
USIO
USIO
481.2% more per $
USIO
-6.7%
-488.0%
OCUL
More free cash flow
USIO
USIO
$58.2M more FCF
USIO
$1.1M
$-57.1M
OCUL
Faster 2-yr revenue CAGR
USIO
USIO
Annualised
USIO
3.0%
-5.3%
OCUL

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
OCUL
OCUL
USIO
USIO
Revenue
$13.3M
$22.2M
Net Profit
$-64.7M
$-1.5M
Gross Margin
88.0%
21.9%
Operating Margin
-526.5%
-5.7%
Net Margin
-488.0%
-6.7%
Revenue YoY
-22.4%
8.2%
Net Profit YoY
-33.6%
-337.8%
EPS (diluted)
$-0.27
$-0.05

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
OCUL
OCUL
USIO
USIO
Q4 25
$13.3M
$22.2M
Q3 25
$14.5M
$21.2M
Q2 25
$13.5M
$20.0M
Q1 25
$10.7M
$22.0M
Q4 24
$17.1M
$20.6M
Q3 24
$15.4M
$21.3M
Q2 24
$16.4M
$20.1M
Q1 24
$14.8M
$21.0M
Net Profit
OCUL
OCUL
USIO
USIO
Q4 25
$-64.7M
$-1.5M
Q3 25
$-69.4M
$-415.1K
Q2 25
$-67.8M
$-366.7K
Q1 25
$-64.1M
$-235.0K
Q4 24
$-48.4M
$628.9K
Q3 24
$-36.5M
$2.9M
Q2 24
$-43.8M
$75.5K
Q1 24
$-64.8M
$-250.2K
Gross Margin
OCUL
OCUL
USIO
USIO
Q4 25
88.0%
21.9%
Q3 25
87.8%
23.0%
Q2 25
85.6%
25.8%
Q1 25
88.2%
21.9%
Q4 24
92.8%
24.6%
Q3 24
89.9%
23.0%
Q2 24
90.8%
23.9%
Q1 24
91.0%
23.1%
Operating Margin
OCUL
OCUL
USIO
USIO
Q4 25
-526.5%
-5.7%
Q3 25
-472.3%
-2.2%
Q2 25
-502.6%
-2.0%
Q1 25
-597.5%
-1.1%
Q4 24
-296.1%
-2.9%
Q3 24
-298.2%
-1.8%
Q2 24
-265.1%
-1.0%
Q1 24
-214.0%
-1.3%
Net Margin
OCUL
OCUL
USIO
USIO
Q4 25
-488.0%
-6.7%
Q3 25
-477.3%
-2.0%
Q2 25
-503.9%
-1.8%
Q1 25
-598.7%
-1.1%
Q4 24
-283.3%
3.1%
Q3 24
-236.6%
13.4%
Q2 24
-266.3%
0.4%
Q1 24
-438.9%
-1.2%
EPS (diluted)
OCUL
OCUL
USIO
USIO
Q4 25
$-0.27
$-0.05
Q3 25
$-0.38
$-0.02
Q2 25
$-0.39
$-0.01
Q1 25
$-0.38
$-0.01
Q4 24
$-0.25
$0.03
Q3 24
$-0.22
$0.10
Q2 24
$-0.26
$0.00
Q1 24
$-0.49
$-0.01

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
OCUL
OCUL
USIO
USIO
Cash + ST InvestmentsLiquidity on hand
$737.1M
$7.4M
Total DebtLower is stronger
$1.4M
Stockholders' EquityBook value
$654.3M
$17.9M
Total Assets
$808.1M
$134.9M
Debt / EquityLower = less leverage
0.08×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
OCUL
OCUL
USIO
USIO
Q4 25
$737.1M
$7.4M
Q3 25
$344.8M
$7.7M
Q2 25
$391.1M
$8.1M
Q1 25
$349.7M
$8.7M
Q4 24
$392.1M
$8.1M
Q3 24
$427.2M
$8.4M
Q2 24
$459.7M
$7.2M
Q1 24
$482.9M
$7.1M
Total Debt
OCUL
OCUL
USIO
USIO
Q4 25
$1.4M
Q3 25
$836.7K
Q2 25
$647.1K
Q1 25
$683.3K
Q4 24
$719.4K
Q3 24
$562.9K
Q2 24
$597.2K
Q1 24
$630.9K
Stockholders' Equity
OCUL
OCUL
USIO
USIO
Q4 25
$654.3M
$17.9M
Q3 25
$258.2M
$18.7M
Q2 25
$305.9M
$18.7M
Q1 25
$265.9M
$19.0M
Q4 24
$315.3M
$19.2M
Q3 24
$352.0M
$18.9M
Q2 24
$377.7M
$15.7M
Q1 24
$408.0M
$15.3M
Total Assets
OCUL
OCUL
USIO
USIO
Q4 25
$808.1M
$134.9M
Q3 25
$410.9M
$99.4M
Q2 25
$451.3M
$108.4M
Q1 25
$405.9M
$109.6M
Q4 24
$457.9M
$107.2M
Q3 24
$490.4M
$114.6M
Q2 24
$517.1M
$108.8M
Q1 24
$538.9M
$99.1M
Debt / Equity
OCUL
OCUL
USIO
USIO
Q4 25
0.08×
Q3 25
0.04×
Q2 25
0.03×
Q1 25
0.04×
Q4 24
0.04×
Q3 24
0.03×
Q2 24
0.04×
Q1 24
0.04×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
OCUL
OCUL
USIO
USIO
Operating Cash FlowLast quarter
$-54.2M
$1.5M
Free Cash FlowOCF − Capex
$-57.1M
$1.1M
FCF MarginFCF / Revenue
-430.9%
4.8%
Capex IntensityCapex / Revenue
21.4%
2.0%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$-216.9M
$1.7M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
OCUL
OCUL
USIO
USIO
Q4 25
$-54.2M
$1.5M
Q3 25
$-50.7M
$303.8K
Q2 25
$-55.2M
$-263.9K
Q1 25
$-44.7M
$1.4M
Q4 24
$-39.4M
$2.9M
Q3 24
$-36.6M
$1.4M
Q2 24
$-24.8M
$369.1K
Q1 24
$-33.9M
$88.7K
Free Cash Flow
OCUL
OCUL
USIO
USIO
Q4 25
$-57.1M
$1.1M
Q3 25
$-56.7M
$85.2K
Q2 25
$-56.5M
$-503.2K
Q1 25
$-46.6M
$1.1M
Q4 24
$-39.6M
$2.7M
Q3 24
$-36.6M
$1.4M
Q2 24
$-25.5M
$246.3K
Q1 24
$-34.1M
$-88.1K
FCF Margin
OCUL
OCUL
USIO
USIO
Q4 25
-430.9%
4.8%
Q3 25
-390.0%
0.4%
Q2 25
-419.7%
-2.5%
Q1 25
-435.6%
4.8%
Q4 24
-232.0%
13.1%
Q3 24
-237.6%
6.4%
Q2 24
-155.4%
1.2%
Q1 24
-231.1%
-0.4%
Capex Intensity
OCUL
OCUL
USIO
USIO
Q4 25
21.4%
2.0%
Q3 25
41.2%
1.0%
Q2 25
9.3%
1.2%
Q1 25
18.1%
1.4%
Q4 24
1.2%
1.0%
Q3 24
0.6%
0.3%
Q2 24
4.5%
0.6%
Q1 24
1.7%
0.8%
Cash Conversion
OCUL
OCUL
USIO
USIO
Q4 25
Q3 25
Q2 25
Q1 25
Q4 24
4.61×
Q3 24
0.50×
Q2 24
4.89×
Q1 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

OCUL
OCUL

Segment breakdown not available.

USIO
USIO

Credit Card Revenue$7.7M35%
ACH And Complementary Service Revenue$6.1M28%
Output Solutions$5.4M24%
Prepaid Card Services Revenue$2.6M12%

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