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Side-by-side financial comparison of OPKO HEALTH, INC. (OPK) and OneStream, Inc. (OS). Click either name above to swap in a different company.

OneStream, Inc. is the larger business by last-quarter revenue ($163.7M vs $148.5M, roughly 1.1× OPKO HEALTH, INC.). OneStream, Inc. runs the higher net margin — 0.6% vs -21.1%, a 21.7% gap on every dollar of revenue. On growth, OneStream, Inc. posted the faster year-over-year revenue change (23.6% vs -19.2%). OneStream, Inc. produced more free cash flow last quarter ($25.6M vs $-28.6M). Over the past eight quarters, OneStream, Inc.'s revenue compounded faster (21.8% CAGR vs -7.5%).

OPKO Health, Inc. is a medical test and medication company focused on diagnostics and pharmaceuticals. The company is a publicly traded company on NASDAQ and TASE under the symbol "OPK".

Blue Stream provides cable television, cable telephone, DVR, and up to 1 GIG Internet speed broadband services to customers in the Florida communities of Coral Springs and Weston.

OPK vs OS — Head-to-Head

Bigger by revenue
OS
OS
1.1× larger
OS
$163.7M
$148.5M
OPK
Growing faster (revenue YoY)
OS
OS
+42.8% gap
OS
23.6%
-19.2%
OPK
Higher net margin
OS
OS
21.7% more per $
OS
0.6%
-21.1%
OPK
More free cash flow
OS
OS
$54.2M more FCF
OS
$25.6M
$-28.6M
OPK
Faster 2-yr revenue CAGR
OS
OS
Annualised
OS
21.8%
-7.5%
OPK

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
OPK
OPK
OS
OS
Revenue
$148.5M
$163.7M
Net Profit
$-31.3M
$999.0K
Gross Margin
43.1%
69.8%
Operating Margin
-25.8%
-3.2%
Net Margin
-21.1%
0.6%
Revenue YoY
-19.2%
23.6%
Net Profit YoY
-322.8%
EPS (diluted)
$-0.04

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
OPK
OPK
OS
OS
Q4 25
$148.5M
$163.7M
Q3 25
$151.7M
$154.3M
Q2 25
$156.8M
$147.6M
Q1 25
$150.0M
$136.3M
Q4 24
$183.6M
$132.5M
Q3 24
$173.6M
$129.1M
Q2 24
$182.2M
$117.5M
Q1 24
$173.7M
$110.3M
Net Profit
OPK
OPK
OS
OS
Q4 25
$-31.3M
$999.0K
Q3 25
$21.6M
$-8.8M
Q2 25
$-148.4M
$-18.4M
Q1 25
$-67.6M
$-24.0M
Q4 24
$14.0M
Q3 24
$24.9M
$-171.9M
Q2 24
$-10.3M
$-7.8M
Q1 24
$-81.8M
$-5.0M
Gross Margin
OPK
OPK
OS
OS
Q4 25
43.1%
69.8%
Q3 25
32.9%
68.1%
Q2 25
31.5%
68.6%
Q1 25
28.4%
68.0%
Q4 24
46.1%
66.8%
Q3 24
23.1%
50.1%
Q2 24
28.4%
68.5%
Q1 24
24.2%
69.1%
Operating Margin
OPK
OPK
OS
OS
Q4 25
-25.8%
-3.2%
Q3 25
31.7%
-11.3%
Q2 25
-38.3%
-21.8%
Q1 25
-44.8%
-29.3%
Q4 24
-18.0%
-35.8%
Q3 24
8.2%
-197.6%
Q2 24
-33.9%
-9.8%
Q1 24
-41.2%
-4.9%
Net Margin
OPK
OPK
OS
OS
Q4 25
-21.1%
0.6%
Q3 25
14.3%
-5.7%
Q2 25
-94.7%
-12.5%
Q1 25
-45.1%
-17.6%
Q4 24
7.6%
Q3 24
14.3%
-133.1%
Q2 24
-5.7%
-6.7%
Q1 24
-47.1%
-4.5%
EPS (diluted)
OPK
OPK
OS
OS
Q4 25
$-0.04
Q3 25
$0.03
Q2 25
$-0.19
Q1 25
$-0.10
Q4 24
$0.02
Q3 24
$0.03
$-1.06
Q2 24
$-0.01
Q1 24
$-0.12

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
OPK
OPK
OS
OS
Cash + ST InvestmentsLiquidity on hand
$364.4M
$693.6M
Total DebtLower is stronger
$344.0M
Stockholders' EquityBook value
$1.3B
$504.7M
Total Assets
$1.9B
$1.0B
Debt / EquityLower = less leverage
0.27×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
OPK
OPK
OS
OS
Q4 25
$364.4M
$693.6M
Q3 25
$412.0M
$653.9M
Q2 25
$267.3M
$652.1M
Q1 25
$428.8M
$593.9M
Q4 24
$426.6M
$544.2M
Q3 24
$400.1M
$495.5M
Q2 24
$40.6M
$140.5M
Q1 24
$75.6M
Total Debt
OPK
OPK
OS
OS
Q4 25
$344.0M
Q3 25
$344.2M
Q2 25
$343.3M
Q1 25
$439.2M
Q4 24
$437.2M
Q3 24
$441.0M
Q2 24
$201.9M
Q1 24
$350.1M
Stockholders' Equity
OPK
OPK
OS
OS
Q4 25
$1.3B
$504.7M
Q3 25
$1.3B
$472.1M
Q2 25
$1.3B
$458.2M
Q1 25
$1.3B
$412.9M
Q4 24
$1.4B
$386.2M
Q3 24
$1.4B
$458.2M
Q2 24
$1.4B
$97.5M
Q1 24
$1.3B
$102.5M
Total Assets
OPK
OPK
OS
OS
Q4 25
$1.9B
$1.0B
Q3 25
$2.0B
$949.4M
Q2 25
$2.0B
$910.5M
Q1 25
$2.1B
$867.3M
Q4 24
$2.2B
$823.2M
Q3 24
$2.3B
$750.1M
Q2 24
$2.0B
$379.7M
Q1 24
$2.0B
Debt / Equity
OPK
OPK
OS
OS
Q4 25
0.27×
Q3 25
0.26×
Q2 25
0.26×
Q1 25
0.33×
Q4 24
0.32×
Q3 24
0.31×
Q2 24
0.14×
Q1 24
0.28×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
OPK
OPK
OS
OS
Operating Cash FlowLast quarter
$-25.9M
$25.8M
Free Cash FlowOCF − Capex
$-28.6M
$25.6M
FCF MarginFCF / Revenue
-19.3%
15.7%
Capex IntensityCapex / Revenue
1.8%
0.1%
Cash ConversionOCF / Net Profit
25.79×
TTM Free Cash FlowTrailing 4 quarters
$-190.8M
$95.6M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
OPK
OPK
OS
OS
Q4 25
$-25.9M
$25.8M
Q3 25
$-34.6M
$5.0M
Q2 25
$-83.4M
$29.7M
Q1 25
$-34.6M
$36.2M
Q4 24
$-44.4M
Q3 24
$-77.1M
$2.4M
Q2 24
$-26.4M
$8.1M
Q1 24
$-35.6M
$25.5M
Free Cash Flow
OPK
OPK
OS
OS
Q4 25
$-28.6M
$25.6M
Q3 25
$-37.8M
$4.8M
Q2 25
$-86.7M
$29.4M
Q1 25
$-37.7M
$35.8M
Q4 24
$-49.8M
Q3 24
$-85.0M
$1.3M
Q2 24
$-33.7M
$7.7M
Q1 24
$-40.0M
$24.9M
FCF Margin
OPK
OPK
OS
OS
Q4 25
-19.3%
15.7%
Q3 25
-24.9%
3.1%
Q2 25
-55.3%
19.9%
Q1 25
-25.2%
26.3%
Q4 24
-27.1%
Q3 24
-49.0%
1.0%
Q2 24
-18.5%
6.6%
Q1 24
-23.0%
22.5%
Capex Intensity
OPK
OPK
OS
OS
Q4 25
1.8%
0.1%
Q3 25
2.1%
0.1%
Q2 25
2.1%
0.2%
Q1 25
2.1%
0.3%
Q4 24
2.9%
Q3 24
4.6%
0.8%
Q2 24
4.0%
0.3%
Q1 24
2.6%
0.6%
Cash Conversion
OPK
OPK
OS
OS
Q4 25
25.79×
Q3 25
-1.60×
Q2 25
Q1 25
Q4 24
-3.17×
Q3 24
-3.10×
Q2 24
Q1 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

OPK
OPK

Services$71.1M48%
Transfer Of Intellectual Property And Other$33.7M23%
IE$22.1M15%
Rayaldee$8.8M6%
Barda Agreement$6.8M5%
MX$6.3M4%

OS
OS

Subscription And Circulation$150.3M92%
Professional Services And Other$9.4M6%
License$4.0M2%

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