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Side-by-side financial comparison of OPKO HEALTH, INC. (OPK) and QUINSTREET, INC (QNST). Click either name above to swap in a different company.

QUINSTREET, INC is the larger business by last-quarter revenue ($287.8M vs $148.5M, roughly 1.9× OPKO HEALTH, INC.). QUINSTREET, INC runs the higher net margin — 17.4% vs -21.1%, a 38.5% gap on every dollar of revenue. On growth, QUINSTREET, INC posted the faster year-over-year revenue change (1.9% vs -19.2%). QUINSTREET, INC produced more free cash flow last quarter ($20.7M vs $-28.6M). Over the past eight quarters, QUINSTREET, INC's revenue compounded faster (53.2% CAGR vs -7.5%).

OPKO Health, Inc. is a medical test and medication company focused on diagnostics and pharmaceuticals. The company is a publicly traded company on NASDAQ and TASE under the symbol "OPK".

QuinStreet, Inc. is a publicly traded online marketing company based in Foster City, California. The company helps generate web traffic for clients by acquiring popular domain names.

OPK vs QNST — Head-to-Head

Bigger by revenue
QNST
QNST
1.9× larger
QNST
$287.8M
$148.5M
OPK
Growing faster (revenue YoY)
QNST
QNST
+21.0% gap
QNST
1.9%
-19.2%
OPK
Higher net margin
QNST
QNST
38.5% more per $
QNST
17.4%
-21.1%
OPK
More free cash flow
QNST
QNST
$49.3M more FCF
QNST
$20.7M
$-28.6M
OPK
Faster 2-yr revenue CAGR
QNST
QNST
Annualised
QNST
53.2%
-7.5%
OPK

Income Statement — Q4 FY2025 vs Q2 FY2026

Metric
OPK
OPK
QNST
QNST
Revenue
$148.5M
$287.8M
Net Profit
$-31.3M
$50.2M
Gross Margin
43.1%
9.6%
Operating Margin
-25.8%
0.4%
Net Margin
-21.1%
17.4%
Revenue YoY
-19.2%
1.9%
Net Profit YoY
-322.8%
3342.5%
EPS (diluted)
$-0.04
$0.87

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
OPK
OPK
QNST
QNST
Q4 25
$148.5M
$287.8M
Q3 25
$151.7M
$285.9M
Q2 25
$156.8M
Q1 25
$150.0M
$269.8M
Q4 24
$183.6M
$282.6M
Q3 24
$173.6M
$279.2M
Q2 24
$182.2M
$198.3M
Q1 24
$173.7M
$168.6M
Net Profit
OPK
OPK
QNST
QNST
Q4 25
$-31.3M
$50.2M
Q3 25
$21.6M
$4.5M
Q2 25
$-148.4M
Q1 25
$-67.6M
$4.4M
Q4 24
$14.0M
$-1.5M
Q3 24
$24.9M
$-1.4M
Q2 24
$-10.3M
$-2.2M
Q1 24
$-81.8M
$-7.0M
Gross Margin
OPK
OPK
QNST
QNST
Q4 25
43.1%
9.6%
Q3 25
32.9%
9.4%
Q2 25
31.5%
Q1 25
28.4%
10.3%
Q4 24
46.1%
9.5%
Q3 24
23.1%
10.2%
Q2 24
28.4%
8.8%
Q1 24
24.2%
8.5%
Operating Margin
OPK
OPK
QNST
QNST
Q4 25
-25.8%
0.4%
Q3 25
31.7%
1.7%
Q2 25
-38.3%
Q1 25
-44.8%
1.8%
Q4 24
-18.0%
-0.5%
Q3 24
8.2%
-0.4%
Q2 24
-33.9%
-0.7%
Q1 24
-41.2%
-3.2%
Net Margin
OPK
OPK
QNST
QNST
Q4 25
-21.1%
17.4%
Q3 25
14.3%
1.6%
Q2 25
-94.7%
Q1 25
-45.1%
1.6%
Q4 24
7.6%
-0.5%
Q3 24
14.3%
-0.5%
Q2 24
-5.7%
-1.1%
Q1 24
-47.1%
-4.2%
EPS (diluted)
OPK
OPK
QNST
QNST
Q4 25
$-0.04
$0.87
Q3 25
$0.03
$0.08
Q2 25
$-0.19
Q1 25
$-0.10
$0.08
Q4 24
$0.02
$-0.03
Q3 24
$0.03
$-0.02
Q2 24
$-0.01
$-0.04
Q1 24
$-0.12
$-0.13

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
OPK
OPK
QNST
QNST
Cash + ST InvestmentsLiquidity on hand
$364.4M
$107.0M
Total DebtLower is stronger
$344.0M
Stockholders' EquityBook value
$1.3B
$294.4M
Total Assets
$1.9B
$493.0M
Debt / EquityLower = less leverage
0.27×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
OPK
OPK
QNST
QNST
Q4 25
$364.4M
$107.0M
Q3 25
$412.0M
$101.3M
Q2 25
$267.3M
Q1 25
$428.8M
$81.8M
Q4 24
$426.6M
$57.8M
Q3 24
$400.1M
$25.0M
Q2 24
$40.6M
$50.5M
Q1 24
$75.6M
$39.6M
Total Debt
OPK
OPK
QNST
QNST
Q4 25
$344.0M
Q3 25
$344.2M
Q2 25
$343.3M
Q1 25
$439.2M
Q4 24
$437.2M
Q3 24
$441.0M
Q2 24
$201.9M
Q1 24
$350.1M
Stockholders' Equity
OPK
OPK
QNST
QNST
Q4 25
$1.3B
$294.4M
Q3 25
$1.3B
$246.7M
Q2 25
$1.3B
Q1 25
$1.3B
$235.5M
Q4 24
$1.4B
$224.3M
Q3 24
$1.4B
$219.8M
Q2 24
$1.4B
$216.8M
Q1 24
$1.3B
$215.0M
Total Assets
OPK
OPK
QNST
QNST
Q4 25
$1.9B
$493.0M
Q3 25
$2.0B
$442.6M
Q2 25
$2.0B
Q1 25
$2.1B
$417.2M
Q4 24
$2.2B
$409.6M
Q3 24
$2.3B
$401.2M
Q2 24
$2.0B
$368.5M
Q1 24
$2.0B
$349.3M
Debt / Equity
OPK
OPK
QNST
QNST
Q4 25
0.27×
Q3 25
0.26×
Q2 25
0.26×
Q1 25
0.33×
Q4 24
0.32×
Q3 24
0.31×
Q2 24
0.14×
Q1 24
0.28×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
OPK
OPK
QNST
QNST
Operating Cash FlowLast quarter
$-25.9M
$21.6M
Free Cash FlowOCF − Capex
$-28.6M
$20.7M
FCF MarginFCF / Revenue
-19.3%
7.2%
Capex IntensityCapex / Revenue
1.8%
0.3%
Cash ConversionOCF / Net Profit
0.43×
TTM Free Cash FlowTrailing 4 quarters
$-190.8M
$106.9M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
OPK
OPK
QNST
QNST
Q4 25
$-25.9M
$21.6M
Q3 25
$-34.6M
$19.6M
Q2 25
$-83.4M
Q1 25
$-34.6M
$30.1M
Q4 24
$-44.4M
$38.7M
Q3 24
$-77.1M
$-13.7M
Q2 24
$-26.4M
$16.6M
Q1 24
$-35.6M
$4.1M
Free Cash Flow
OPK
OPK
QNST
QNST
Q4 25
$-28.6M
$20.7M
Q3 25
$-37.8M
$18.4M
Q2 25
$-86.7M
Q1 25
$-37.7M
$29.5M
Q4 24
$-49.8M
$38.2M
Q3 24
$-85.0M
$-14.1M
Q2 24
$-33.7M
$15.4M
Q1 24
$-40.0M
$2.9M
FCF Margin
OPK
OPK
QNST
QNST
Q4 25
-19.3%
7.2%
Q3 25
-24.9%
6.4%
Q2 25
-55.3%
Q1 25
-25.2%
10.9%
Q4 24
-27.1%
13.5%
Q3 24
-49.0%
-5.1%
Q2 24
-18.5%
7.8%
Q1 24
-23.0%
1.7%
Capex Intensity
OPK
OPK
QNST
QNST
Q4 25
1.8%
0.3%
Q3 25
2.1%
0.4%
Q2 25
2.1%
Q1 25
2.1%
0.2%
Q4 24
2.9%
0.2%
Q3 24
4.6%
0.2%
Q2 24
4.0%
0.6%
Q1 24
2.6%
0.7%
Cash Conversion
OPK
OPK
QNST
QNST
Q4 25
0.43×
Q3 25
-1.60×
4.32×
Q2 25
Q1 25
6.82×
Q4 24
-3.17×
Q3 24
-3.10×
Q2 24
Q1 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

OPK
OPK

Services$71.1M48%
Transfer Of Intellectual Property And Other$33.7M23%
IE$22.1M15%
Rayaldee$8.8M6%
Barda Agreement$6.8M5%
MX$6.3M4%

QNST
QNST

Financial Service$216.8M75%
Home Services And Other Revenue$71.0M25%

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