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Side-by-side financial comparison of ORASURE TECHNOLOGIES INC (OSUR) and System1, Inc. (SST). Click either name above to swap in a different company.
System1, Inc. is the larger business by last-quarter revenue ($51.9M vs $26.8M, roughly 1.9× ORASURE TECHNOLOGIES INC). System1, Inc. runs the higher net margin — -26.0% vs -72.1%, a 46.1% gap on every dollar of revenue. On growth, ORASURE TECHNOLOGIES INC posted the faster year-over-year revenue change (-28.5% vs -31.3%). Over the past eight quarters, System1, Inc.'s revenue compounded faster (-21.8% CAGR vs -29.7%).
OraSure Technologies, Inc. is a Bethlehem, Pennsylvania–based company in the medical device industry. Their products include diagnostic testing kits. The company had recently developed OraQuick testing kit, the first over-the-counter home HIV test.
System1 is an American Internet advertising company. Formerly known as OpenMail, it was founded in 2013. It describes itself as operating a "Responsive Acquisition Marketing Platform", and cites privacy as one of its principal foci, although it has been criticized for its influence on privacy-focused properties, including search engine Startpage.com. It is headquartered in Marina del Rey, California.
OSUR vs SST — Head-to-Head
Income Statement — Q4 FY2025 vs Q4 FY2025
| Metric | | |
|---|---|---|
| Revenue | $26.8M | $51.9M |
| Net Profit | $-19.3M | $-13.5M |
| Gross Margin | 41.0% | 41.0% |
| Operating Margin | -75.1% | -33.6% |
| Net Margin | -72.1% | -26.0% |
| Revenue YoY | -28.5% | -31.3% |
| Net Profit YoY | -78.7% | 4.8% |
| EPS (diluted) | $-0.28 | $-3.58 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q4 25 | $26.8M | $51.9M | ||
| Q3 25 | $27.1M | $61.6M | ||
| Q2 25 | $31.2M | $78.1M | ||
| Q1 25 | $29.9M | $74.5M | ||
| Q4 24 | $37.4M | $75.6M | ||
| Q3 24 | $39.9M | $88.8M | ||
| Q2 24 | $54.3M | $94.6M | ||
| Q1 24 | $54.1M | $84.9M |
| Q4 25 | $-19.3M | $-13.5M | ||
| Q3 25 | $-13.7M | $-18.5M | ||
| Q2 25 | $-19.7M | $-17.5M | ||
| Q1 25 | $-16.0M | $-15.9M | ||
| Q4 24 | $-10.8M | $-14.2M | ||
| Q3 24 | $-4.5M | $-23.6M | ||
| Q2 24 | $-615.0K | $-26.4M | ||
| Q1 24 | $-3.6M | $-10.5M |
| Q4 25 | 41.0% | 41.0% | ||
| Q3 25 | 43.5% | 36.9% | ||
| Q2 25 | 42.1% | 35.7% | ||
| Q1 25 | 41.1% | 38.2% | ||
| Q4 24 | 36.2% | 42.1% | ||
| Q3 24 | 42.8% | 28.0% | ||
| Q2 24 | 45.4% | 27.6% | ||
| Q1 24 | 44.5% | 21.9% |
| Q4 25 | -75.1% | -33.6% | ||
| Q3 25 | -59.4% | -25.3% | ||
| Q2 25 | -57.7% | -20.4% | ||
| Q1 25 | -59.3% | -17.6% | ||
| Q4 24 | -33.2% | -15.7% | ||
| Q3 24 | -15.0% | -24.6% | ||
| Q2 24 | -5.0% | -30.8% | ||
| Q1 24 | -13.1% | -30.4% |
| Q4 25 | -72.1% | -26.0% | ||
| Q3 25 | -50.6% | -30.1% | ||
| Q2 25 | -63.0% | -22.4% | ||
| Q1 25 | -53.6% | -21.3% | ||
| Q4 24 | -28.8% | -18.7% | ||
| Q3 24 | -11.3% | -26.6% | ||
| Q2 24 | -1.1% | -27.9% | ||
| Q1 24 | -6.6% | -12.4% |
| Q4 25 | $-0.28 | $-3.58 | ||
| Q3 25 | $-0.19 | $-2.30 | ||
| Q2 25 | $-0.26 | $-2.23 | ||
| Q1 25 | $-0.21 | $-0.21 | ||
| Q4 24 | $-0.14 | $-3.41 | ||
| Q3 24 | $-0.06 | $-3.37 | ||
| Q2 24 | $-0.01 | $-3.80 | ||
| Q1 24 | $-0.05 | $-0.16 |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $199.3M | $86.9M |
| Total DebtLower is stronger | — | $305.1M |
| Stockholders' EquityBook value | $340.8M | $30.5M |
| Total Assets | $403.2M | $405.0M |
| Debt / EquityLower = less leverage | — | 10.01× |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $199.3M | $86.9M | ||
| Q3 25 | $216.5M | $54.6M | ||
| Q2 25 | $234.6M | $63.6M | ||
| Q1 25 | $247.6M | $43.9M | ||
| Q4 24 | $267.8M | $63.6M | ||
| Q3 24 | $278.6M | $69.1M | ||
| Q2 24 | $267.4M | $75.7M | ||
| Q1 24 | $263.8M | $69.9M |
| Q4 25 | — | $305.1M | ||
| Q3 25 | — | $259.2M | ||
| Q2 25 | — | $263.3M | ||
| Q1 25 | — | $267.4M | ||
| Q4 24 | — | $255.1M | ||
| Q3 24 | — | $259.2M | ||
| Q2 24 | — | $263.3M | ||
| Q1 24 | — | $268.6M |
| Q4 25 | $340.8M | $30.5M | ||
| Q3 25 | $362.0M | $42.7M | ||
| Q2 25 | $380.7M | $58.2M | ||
| Q1 25 | $396.3M | $67.2M | ||
| Q4 24 | $410.3M | $80.3M | ||
| Q3 24 | $425.6M | $90.3M | ||
| Q2 24 | $425.8M | $109.4M | ||
| Q1 24 | $426.3M | $131.7M |
| Q4 25 | $403.2M | $405.0M | ||
| Q3 25 | $423.1M | $385.2M | ||
| Q2 25 | $445.0M | $429.2M | ||
| Q1 25 | $457.6M | $419.2M | ||
| Q4 24 | $479.7M | $459.1M | ||
| Q3 24 | $464.1M | $479.3M | ||
| Q2 24 | $466.3M | $511.3M | ||
| Q1 24 | $467.6M | $521.1M |
| Q4 25 | — | 10.01× | ||
| Q3 25 | — | 6.07× | ||
| Q2 25 | — | 4.53× | ||
| Q1 25 | — | 3.98× | ||
| Q4 24 | — | 3.18× | ||
| Q3 24 | — | 2.87× | ||
| Q2 24 | — | 2.41× | ||
| Q1 24 | — | 2.04× |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | $-9.0M | $-10.6M |
| Free Cash FlowOCF − Capex | $-9.9M | — |
| FCF MarginFCF / Revenue | -37.1% | — |
| Capex IntensityCapex / Revenue | 3.4% | 0.0% |
| Cash ConversionOCF / Net Profit | — | — |
| TTM Free Cash FlowTrailing 4 quarters | $-53.2M | — |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $-9.0M | $-10.6M | ||
| Q3 25 | $-10.1M | $-2.1M | ||
| Q2 25 | $-10.2M | $24.5M | ||
| Q1 25 | $-19.7M | $-15.9M | ||
| Q4 24 | $109.0K | $772.0K | ||
| Q3 24 | $12.7M | $-5.0K | ||
| Q2 24 | $7.8M | $10.0M | ||
| Q1 24 | $6.7M | $-16.0M |
| Q4 25 | $-9.9M | — | ||
| Q3 25 | $-11.0M | — | ||
| Q2 25 | $-12.2M | — | ||
| Q1 25 | $-20.2M | $-16.0M | ||
| Q4 24 | $-347.0K | — | ||
| Q3 24 | $12.5M | $-36.0K | ||
| Q2 24 | $6.2M | — | ||
| Q1 24 | $5.2M | — |
| Q4 25 | -37.1% | — | ||
| Q3 25 | -40.6% | — | ||
| Q2 25 | -38.9% | — | ||
| Q1 25 | -67.3% | -21.5% | ||
| Q4 24 | -0.9% | — | ||
| Q3 24 | 31.4% | -0.0% | ||
| Q2 24 | 11.5% | — | ||
| Q1 24 | 9.5% | — |
| Q4 25 | 3.4% | 0.0% | ||
| Q3 25 | 3.4% | 0.0% | ||
| Q2 25 | 6.2% | 0.0% | ||
| Q1 25 | 1.4% | 0.1% | ||
| Q4 24 | 1.2% | 0.0% | ||
| Q3 24 | 0.4% | 0.0% | ||
| Q2 24 | 3.0% | 0.0% | ||
| Q1 24 | 2.9% | 0.0% |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
Revenue Breakdown by Segment
OSUR
| Product And Services | $24.9M | 93% |
| Other | $1.9M | 7% |
SST
Segment breakdown not available.
