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Side-by-side financial comparison of ORASURE TECHNOLOGIES INC (OSUR) and STEM, INC. (STEM). Click either name above to swap in a different company.
STEM, INC. is the larger business by last-quarter revenue ($47.1M vs $26.8M, roughly 1.8× ORASURE TECHNOLOGIES INC). STEM, INC. runs the higher net margin — -33.9% vs -72.1%, a 38.2% gap on every dollar of revenue. On growth, STEM, INC. posted the faster year-over-year revenue change (-15.6% vs -28.5%). Over the past eight quarters, STEM, INC.'s revenue compounded faster (36.1% CAGR vs -29.7%).
OraSure Technologies, Inc. is a Bethlehem, Pennsylvania–based company in the medical device industry. Their products include diagnostic testing kits. The company had recently developed OraQuick testing kit, the first over-the-counter home HIV test.
StemCells, Inc. is a public biopharmaceutical company headquartered in Newark, California, that is developing purified human neural stem cells (HuCNS-SCs) in the hopes of treating central nervous system disorders and paralysis. StemCells' HuCNS-SCs have the ability to differentiate into the three main types of cells found in the central nervous system: neurons, astrocytes and oligodendrocytes.
OSUR vs STEM — Head-to-Head
Income Statement — Q4 FY2025 vs Q4 FY2025
| Metric | | |
|---|---|---|
| Revenue | $26.8M | $47.1M |
| Net Profit | $-19.3M | $-16.0M |
| Gross Margin | 41.0% | 48.9% |
| Operating Margin | -75.1% | -17.7% |
| Net Margin | -72.1% | -33.9% |
| Revenue YoY | -28.5% | -15.6% |
| Net Profit YoY | -78.7% | 68.8% |
| EPS (diluted) | $-0.28 | $-4.40 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q4 25 | $26.8M | $47.1M | ||
| Q3 25 | $27.1M | $38.2M | ||
| Q2 25 | $31.2M | $38.4M | ||
| Q1 25 | $29.9M | $32.5M | ||
| Q4 24 | $37.4M | $55.8M | ||
| Q3 24 | $39.9M | $29.3M | ||
| Q2 24 | $54.3M | $34.0M | ||
| Q1 24 | $54.1M | $25.5M |
| Q4 25 | $-19.3M | $-16.0M | ||
| Q3 25 | $-13.7M | $-23.8M | ||
| Q2 25 | $-19.7M | $202.5M | ||
| Q1 25 | $-16.0M | $-25.0M | ||
| Q4 24 | $-10.8M | $-51.1M | ||
| Q3 24 | $-4.5M | $-148.3M | ||
| Q2 24 | $-615.0K | $-582.3M | ||
| Q1 24 | $-3.6M | $-72.3M |
| Q4 25 | 41.0% | 48.9% | ||
| Q3 25 | 43.5% | 35.5% | ||
| Q2 25 | 42.1% | 33.4% | ||
| Q1 25 | 41.1% | 32.4% | ||
| Q4 24 | 36.2% | -4.4% | ||
| Q3 24 | 42.8% | 21.2% | ||
| Q2 24 | 45.4% | 27.6% | ||
| Q1 24 | 44.5% | -95.0% |
| Q4 25 | -75.1% | -17.7% | ||
| Q3 25 | -59.4% | -33.6% | ||
| Q2 25 | -57.7% | -34.8% | ||
| Q1 25 | -59.3% | -65.0% | ||
| Q4 24 | -33.2% | -84.4% | ||
| Q3 24 | -15.0% | -493.2% | ||
| Q2 24 | -5.0% | -1705.5% | ||
| Q1 24 | -13.1% | -267.0% |
| Q4 25 | -72.1% | -33.9% | ||
| Q3 25 | -50.6% | -62.2% | ||
| Q2 25 | -63.0% | 527.8% | ||
| Q1 25 | -53.6% | -76.9% | ||
| Q4 24 | -28.8% | -91.6% | ||
| Q3 24 | -11.3% | -506.3% | ||
| Q2 24 | -1.1% | -1712.6% | ||
| Q1 24 | -6.6% | -283.9% |
| Q4 25 | $-0.28 | $-4.40 | ||
| Q3 25 | $-0.19 | $-2.84 | ||
| Q2 25 | $-0.26 | $-1.79 | ||
| Q1 25 | $-0.21 | $-0.15 | ||
| Q4 24 | $-0.14 | $-15.29 | ||
| Q3 24 | $-0.06 | $-18.24 | ||
| Q2 24 | $-0.01 | $-71.81 | ||
| Q1 24 | $-0.05 | $-0.46 |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $199.3M | $48.9M |
| Total DebtLower is stronger | — | — |
| Stockholders' EquityBook value | $340.8M | $-249.4M |
| Total Assets | $403.2M | $308.9M |
| Debt / EquityLower = less leverage | — | — |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $199.3M | $48.9M | ||
| Q3 25 | $216.5M | $43.1M | ||
| Q2 25 | $234.6M | $40.8M | ||
| Q1 25 | $247.6M | $58.6M | ||
| Q4 24 | $267.8M | $56.3M | ||
| Q3 24 | $278.6M | $75.4M | ||
| Q2 24 | $267.4M | $89.6M | ||
| Q1 24 | $263.8M | $112.8M |
| Q4 25 | $340.8M | $-249.4M | ||
| Q3 25 | $362.0M | $-235.7M | ||
| Q2 25 | $380.7M | $-214.1M | ||
| Q1 25 | $396.3M | $-417.5M | ||
| Q4 24 | $410.3M | $-398.4M | ||
| Q3 24 | $425.6M | $-344.1M | ||
| Q2 24 | $425.8M | $-203.2M | ||
| Q1 24 | $426.3M | $371.6M |
| Q4 25 | $403.2M | $308.9M | ||
| Q3 25 | $423.1M | $362.6M | ||
| Q2 25 | $445.0M | $379.2M | ||
| Q1 25 | $457.6M | $405.1M | ||
| Q4 24 | $479.7M | $437.4M | ||
| Q3 24 | $464.1M | $537.8M | ||
| Q2 24 | $466.3M | $691.5M | ||
| Q1 24 | $467.6M | $1.3B |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | $-9.0M | $8.2M |
| Free Cash FlowOCF − Capex | $-9.9M | — |
| FCF MarginFCF / Revenue | -37.1% | — |
| Capex IntensityCapex / Revenue | 3.4% | — |
| Cash ConversionOCF / Net Profit | — | — |
| TTM Free Cash FlowTrailing 4 quarters | $-53.2M | — |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $-9.0M | $8.2M | ||
| Q3 25 | $-10.1M | $11.4M | ||
| Q2 25 | $-10.2M | $-21.3M | ||
| Q1 25 | $-19.7M | $8.5M | ||
| Q4 24 | $109.0K | $-14.7M | ||
| Q3 24 | $12.7M | $-9.4M | ||
| Q2 24 | $7.8M | $-11.9M | ||
| Q1 24 | $6.7M | $-621.0K |
| Q4 25 | $-9.9M | — | ||
| Q3 25 | $-11.0M | — | ||
| Q2 25 | $-12.2M | — | ||
| Q1 25 | $-20.2M | — | ||
| Q4 24 | $-347.0K | — | ||
| Q3 24 | $12.5M | — | ||
| Q2 24 | $6.2M | — | ||
| Q1 24 | $5.2M | — |
| Q4 25 | -37.1% | — | ||
| Q3 25 | -40.6% | — | ||
| Q2 25 | -38.9% | — | ||
| Q1 25 | -67.3% | — | ||
| Q4 24 | -0.9% | — | ||
| Q3 24 | 31.4% | — | ||
| Q2 24 | 11.5% | — | ||
| Q1 24 | 9.5% | — |
| Q4 25 | 3.4% | — | ||
| Q3 25 | 3.4% | — | ||
| Q2 25 | 6.2% | — | ||
| Q1 25 | 1.4% | — | ||
| Q4 24 | 1.2% | — | ||
| Q3 24 | 0.4% | — | ||
| Q2 24 | 3.0% | — | ||
| Q1 24 | 2.9% | — |
| Q4 25 | — | — | ||
| Q3 25 | — | — | ||
| Q2 25 | — | -0.11× | ||
| Q1 25 | — | — | ||
| Q4 24 | — | — | ||
| Q3 24 | — | — | ||
| Q2 24 | — | — | ||
| Q1 24 | — | — |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
Revenue Breakdown by Segment
OSUR
| Product And Services | $24.9M | 93% |
| Other | $1.9M | 7% |
STEM
Segment breakdown not available.
