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Side-by-side financial comparison of Palo Alto Networks (PANW) and Vertex Pharmaceuticals (VRTX). Click either name above to swap in a different company.

Vertex Pharmaceuticals is the larger business by last-quarter revenue ($3.2B vs $2.6B, roughly 1.2× Palo Alto Networks). Vertex Pharmaceuticals runs the higher net margin — 37.3% vs 16.7%, a 20.7% gap on every dollar of revenue. On growth, Palo Alto Networks posted the faster year-over-year revenue change (14.9% vs 9.5%). Palo Alto Networks produced more free cash flow last quarter ($384.0M vs $348.6M). Over the past eight quarters, Palo Alto Networks's revenue compounded faster (14.3% CAGR vs 8.9%).

Palo Alto Networks, Inc. is an American multinational cybersecurity company with headquarters in Santa Clara, California. The core product is a platform that includes advanced firewalls and cloud-based offerings that extend those firewalls to cover other aspects of security. The company serves over 70,000 organizations in over 150 countries, including 85 of the Fortune 100. It is home to the Unit 42 threat research team and hosts the Ignite cybersecurity conference.

Vertex Pharmaceuticals Incorporated is an American biopharmaceutical company based in Boston, Massachusetts. It was one of the first biotech firms to use an explicit strategy of rational drug design rather than combinatorial chemistry. It maintains headquarters in Boston, Massachusetts, and three research facilities, in San Diego, California, and Milton Park, Oxfordshire, England.

PANW vs VRTX — Head-to-Head

Bigger by revenue
VRTX
VRTX
1.2× larger
VRTX
$3.2B
$2.6B
PANW
Growing faster (revenue YoY)
PANW
PANW
+5.4% gap
PANW
14.9%
9.5%
VRTX
Higher net margin
VRTX
VRTX
20.7% more per $
VRTX
37.3%
16.7%
PANW
More free cash flow
PANW
PANW
$35.4M more FCF
PANW
$384.0M
$348.6M
VRTX
Faster 2-yr revenue CAGR
PANW
PANW
Annualised
PANW
14.3%
8.9%
VRTX

Income Statement — Q2 FY2026 vs Q4 FY2025

Metric
PANW
PANW
VRTX
VRTX
Revenue
$2.6B
$3.2B
Net Profit
$432.0M
$1.2B
Gross Margin
73.6%
85.4%
Operating Margin
15.3%
37.8%
Net Margin
16.7%
37.3%
Revenue YoY
14.9%
9.5%
Net Profit YoY
61.6%
30.5%
EPS (diluted)
$0.61
$4.64

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
PANW
PANW
VRTX
VRTX
Q1 26
$2.6B
Q4 25
$2.5B
$3.2B
Q3 25
$2.5B
$3.1B
Q2 25
$2.3B
$3.0B
Q1 25
$2.3B
$2.8B
Q4 24
$2.1B
$2.9B
Q3 24
$2.2B
$2.8B
Q2 24
$2.0B
$2.6B
Net Profit
PANW
PANW
VRTX
VRTX
Q1 26
$432.0M
Q4 25
$334.0M
$1.2B
Q3 25
$253.8M
$1.1B
Q2 25
$262.1M
$1.0B
Q1 25
$267.3M
$646.3M
Q4 24
$350.7M
$913.0M
Q3 24
$357.7M
$1.0B
Q2 24
$278.8M
$-3.6B
Gross Margin
PANW
PANW
VRTX
VRTX
Q1 26
73.6%
Q4 25
74.2%
85.4%
Q3 25
73.2%
86.5%
Q2 25
72.9%
86.3%
Q1 25
73.5%
86.9%
Q4 24
74.1%
85.5%
Q3 24
73.8%
85.8%
Q2 24
74.1%
85.9%
Operating Margin
PANW
PANW
VRTX
VRTX
Q1 26
15.3%
Q4 25
12.5%
37.8%
Q3 25
19.6%
38.6%
Q2 25
9.6%
38.8%
Q1 25
10.6%
22.7%
Q4 24
13.4%
35.2%
Q3 24
10.9%
40.3%
Q2 24
8.9%
-132.9%
Net Margin
PANW
PANW
VRTX
VRTX
Q1 26
16.7%
Q4 25
13.5%
37.3%
Q3 25
10.0%
35.2%
Q2 25
11.5%
34.8%
Q1 25
11.8%
23.3%
Q4 24
16.4%
31.4%
Q3 24
16.3%
37.7%
Q2 24
14.0%
-135.8%
EPS (diluted)
PANW
PANW
VRTX
VRTX
Q1 26
$0.61
Q4 25
$0.47
$4.64
Q3 25
$-0.14
$4.20
Q2 25
$0.37
$3.99
Q1 25
$0.38
$2.49
Q4 24
$0.99
$3.62
Q3 24
$1.04
$4.01
Q2 24
$0.79
$-13.92

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
PANW
PANW
VRTX
VRTX
Cash + ST InvestmentsLiquidity on hand
$4.5B
$6.6B
Total DebtLower is stronger
Stockholders' EquityBook value
$9.4B
$18.7B
Total Assets
$25.0B
$25.6B
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
PANW
PANW
VRTX
VRTX
Q1 26
$4.5B
Q4 25
$4.2B
$6.6B
Q3 25
$2.9B
$6.3B
Q2 25
$3.3B
$6.4B
Q1 25
$3.2B
$6.2B
Q4 24
$3.4B
$6.1B
Q3 24
$2.6B
$6.5B
Q2 24
$2.9B
$5.8B
Stockholders' Equity
PANW
PANW
VRTX
VRTX
Q1 26
$9.4B
Q4 25
$8.7B
$18.7B
Q3 25
$7.8B
$17.3B
Q2 25
$7.2B
$17.2B
Q1 25
$6.4B
$16.5B
Q4 24
$5.9B
$16.4B
Q3 24
$5.2B
$15.6B
Q2 24
$4.5B
$14.8B
Total Assets
PANW
PANW
VRTX
VRTX
Q1 26
$25.0B
Q4 25
$23.5B
$25.6B
Q3 25
$23.6B
$24.9B
Q2 25
$22.0B
$24.0B
Q1 25
$21.0B
$22.9B
Q4 24
$20.4B
$22.5B
Q3 24
$20.0B
$22.2B
Q2 24
$17.9B
$20.1B

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
PANW
PANW
VRTX
VRTX
Operating Cash FlowLast quarter
$554.0M
$498.0M
Free Cash FlowOCF − Capex
$384.0M
$348.6M
FCF MarginFCF / Revenue
14.8%
10.9%
Capex IntensityCapex / Revenue
6.6%
4.7%
Cash ConversionOCF / Net Profit
1.28×
0.42×
TTM Free Cash FlowTrailing 4 quarters
$3.6B
$3.2B

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
PANW
PANW
VRTX
VRTX
Q1 26
$554.0M
Q4 25
$1.8B
$498.0M
Q3 25
$1.0B
$1.2B
Q2 25
$628.7M
$1.1B
Q1 25
$556.9M
$818.9M
Q4 24
$1.5B
$584.6M
Q3 24
$512.7M
$1.4B
Q2 24
$528.9M
$-3.8B
Free Cash Flow
PANW
PANW
VRTX
VRTX
Q1 26
$384.0M
Q4 25
$1.7B
$348.6M
Q3 25
$934.5M
$1.1B
Q2 25
$560.4M
$927.4M
Q1 25
$509.4M
$778.2M
Q4 24
$1.5B
$492.0M
Q3 24
$465.3M
$1.3B
Q2 24
$491.5M
$-3.8B
FCF Margin
PANW
PANW
VRTX
VRTX
Q1 26
14.8%
Q4 25
68.2%
10.9%
Q3 25
36.8%
37.0%
Q2 25
24.5%
31.3%
Q1 25
22.6%
28.1%
Q4 24
68.5%
16.9%
Q3 24
21.3%
47.0%
Q2 24
24.8%
-144.5%
Capex Intensity
PANW
PANW
VRTX
VRTX
Q1 26
6.6%
Q4 25
3.4%
4.7%
Q3 25
3.4%
3.3%
Q2 25
3.0%
4.9%
Q1 25
2.1%
1.5%
Q4 24
2.1%
3.2%
Q3 24
2.2%
2.4%
Q2 24
1.9%
2.6%
Cash Conversion
PANW
PANW
VRTX
VRTX
Q1 26
1.28×
Q4 25
5.30×
0.42×
Q3 25
4.02×
1.15×
Q2 25
2.40×
1.04×
Q1 25
2.08×
1.27×
Q4 24
4.30×
0.64×
Q3 24
1.43×
1.31×
Q2 24
1.90×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

PANW
PANW

Subscription$1.4B54%
Support$676.0M26%
Products$514.0M20%

VRTX
VRTX

TRIKAFTAKAFTRIO$2.6B81%
ALYFTREK$380.1M12%
Manufactured Product Other$237.4M7%

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