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Side-by-side financial comparison of Pioneer Bancorp, Inc. (PBFS) and Septerna, Inc. (SEPN). Click either name above to swap in a different company.

Pioneer Bancorp, Inc. is the larger business by last-quarter revenue ($25.0M vs $24.1M, roughly 1.0× Septerna, Inc.). Pioneer Bancorp, Inc. runs the higher net margin — 82.1% vs -44.5%, a 126.6% gap on every dollar of revenue.

Pioneer Bancorp, Inc. (MD) is a bank holding company operating as the parent entity of Pioneer Bank. It provides a full suite of retail and commercial banking products and services, including deposit accounts, residential and commercial mortgages, consumer loans, and small business financing, primarily serving individual and corporate customers across local communities in Maryland, U.S.

Septerna, Inc. is a clinical-stage biotechnology company focused on developing novel therapies targeting G protein-coupled receptors (GPCRs), a large family of cell surface proteins involved in many disease pathways. Its pipeline includes candidates for inflammatory, metabolic, and central nervous system disorders, addressing global unmet medical needs.

PBFS vs SEPN — Head-to-Head

Bigger by revenue
PBFS
PBFS
1.0× larger
PBFS
$25.0M
$24.1M
SEPN
Higher net margin
PBFS
PBFS
126.6% more per $
PBFS
82.1%
-44.5%
SEPN

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
PBFS
PBFS
SEPN
SEPN
Revenue
$25.0M
$24.1M
Net Profit
$3.7M
$-10.7M
Gross Margin
Operating Margin
21.3%
-66.4%
Net Margin
82.1%
-44.5%
Revenue YoY
Net Profit YoY
EPS (diluted)
$0.16
$-0.23

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
PBFS
PBFS
SEPN
SEPN
Q4 25
$25.0M
$24.1M
Q3 25
$24.0M
$21.5M
Q2 25
$24.4M
Q1 25
$22.8M
Q3 24
$22.0M
Q2 24
$20.9M
Q1 24
$21.6M
Q4 23
$4.2M
Net Profit
PBFS
PBFS
SEPN
SEPN
Q4 25
$3.7M
$-10.7M
Q3 25
$4.3M
$8.2M
Q2 25
$6.5M
Q1 25
$5.8M
Q3 24
$6.3M
Q2 24
$3.9M
Q1 24
$4.7M
Q4 23
$3.2M
Operating Margin
PBFS
PBFS
SEPN
SEPN
Q4 25
21.3%
-66.4%
Q3 25
23.4%
12.2%
Q2 25
33.3%
Q1 25
32.5%
Q3 24
37.2%
Q2 24
24.1%
Q1 24
28.1%
Q4 23
96.1%
Net Margin
PBFS
PBFS
SEPN
SEPN
Q4 25
82.1%
-44.5%
Q3 25
18.0%
38.0%
Q2 25
26.4%
Q1 25
25.3%
Q3 24
28.7%
Q2 24
107.4%
Q1 24
21.9%
Q4 23
76.4%
EPS (diluted)
PBFS
PBFS
SEPN
SEPN
Q4 25
$0.16
$-0.23
Q3 25
$0.18
$0.18
Q2 25
$0.26
Q1 25
$0.23
Q3 24
$0.25
Q2 24
$0.15
Q1 24
$0.19
Q4 23
$0.13

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
PBFS
PBFS
SEPN
SEPN
Cash + ST InvestmentsLiquidity on hand
$391.1M
Total DebtLower is stronger
Stockholders' EquityBook value
$323.9M
$381.9M
Total Assets
$2.2B
$596.2M
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
PBFS
PBFS
SEPN
SEPN
Q4 25
$391.1M
Q3 25
$474.3M
Q2 25
Q1 25
Q3 24
Q2 24
Q1 24
Q4 23
Stockholders' Equity
PBFS
PBFS
SEPN
SEPN
Q4 25
$323.9M
$381.9M
Q3 25
$314.2M
$388.7M
Q2 25
$314.2M
Q1 25
$310.7M
Q3 24
$303.8M
Q2 24
$296.5M
Q1 24
$289.0M
Q4 23
$283.8M
Total Assets
PBFS
PBFS
SEPN
SEPN
Q4 25
$2.2B
$596.2M
Q3 25
$2.2B
$606.7M
Q2 25
$2.1B
Q1 25
$2.1B
Q3 24
$2.0B
Q2 24
Q1 24
$2.0B
Q4 23
$1.9B

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
PBFS
PBFS
SEPN
SEPN
Operating Cash FlowLast quarter
$11.1M
$-15.0M
Free Cash FlowOCF − Capex
$-15.1M
FCF MarginFCF / Revenue
-62.4%
Capex IntensityCapex / Revenue
0.3%
Cash ConversionOCF / Net Profit
2.97×
TTM Free Cash FlowTrailing 4 quarters

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
PBFS
PBFS
SEPN
SEPN
Q4 25
$11.1M
$-15.0M
Q3 25
$3.9M
$168.8M
Q2 25
$5.1M
Q1 25
$-3.5M
Q3 24
$1.9M
Q2 24
$9.0M
Q1 24
$3.3M
Q4 23
$-943.0K
Free Cash Flow
PBFS
PBFS
SEPN
SEPN
Q4 25
$-15.1M
Q3 25
$168.8M
Q2 25
Q1 25
Q3 24
Q2 24
Q1 24
Q4 23
FCF Margin
PBFS
PBFS
SEPN
SEPN
Q4 25
-62.4%
Q3 25
785.3%
Q2 25
Q1 25
Q3 24
Q2 24
Q1 24
Q4 23
Capex Intensity
PBFS
PBFS
SEPN
SEPN
Q4 25
0.3%
Q3 25
0.1%
Q2 25
Q1 25
Q3 24
Q2 24
Q1 24
Q4 23
Cash Conversion
PBFS
PBFS
SEPN
SEPN
Q4 25
2.97×
Q3 25
0.90×
20.65×
Q2 25
0.78×
Q1 25
-0.61×
Q3 24
0.30×
Q2 24
2.30×
Q1 24
0.70×
Q4 23
-0.30×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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