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Side-by-side financial comparison of PUMA BIOTECHNOLOGY, INC. (PBYI) and Safehold Inc. (SAFE). Click either name above to swap in a different company.
Safehold Inc. is the larger business by last-quarter revenue ($97.9M vs $75.5M, roughly 1.3× PUMA BIOTECHNOLOGY, INC.). On growth, PUMA BIOTECHNOLOGY, INC. posted the faster year-over-year revenue change (27.7% vs 6.5%). Over the past eight quarters, PUMA BIOTECHNOLOGY, INC.'s revenue compounded faster (31.3% CAGR vs 2.5%).
Puma Biotechnology is a publicly traded biopharmaceutical company headquartered in Los Angeles, CA.
SAFE Investment Company Limited is a Chinese sovereign wealth fund based in Hong Kong.
PBYI vs SAFE — Head-to-Head
Income Statement — Q4 FY2025 vs Q4 FY2025
| Metric | | |
|---|---|---|
| Revenue | $75.5M | $97.9M |
| Net Profit | — | $27.9M |
| Gross Margin | 69.3% | 98.6% |
| Operating Margin | 22.7% | 27.4% |
| Net Margin | — | 28.5% |
| Revenue YoY | 27.7% | 6.5% |
| Net Profit YoY | — | 7.1% |
| EPS (diluted) | $0.26 | $0.38 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q4 25 | $75.5M | $97.9M | ||
| Q3 25 | $54.5M | $96.2M | ||
| Q2 25 | $52.4M | $93.8M | ||
| Q1 25 | $46.0M | $97.7M | ||
| Q4 24 | $59.1M | $91.9M | ||
| Q3 24 | $80.5M | $90.7M | ||
| Q2 24 | $47.1M | $89.9M | ||
| Q1 24 | $43.8M | $93.2M |
| Q4 25 | — | $27.9M | ||
| Q3 25 | $8.8M | $29.3M | ||
| Q2 25 | $5.9M | $27.9M | ||
| Q1 25 | $3.0M | $29.4M | ||
| Q4 24 | — | $26.0M | ||
| Q3 24 | $20.3M | $19.3M | ||
| Q2 24 | $-4.5M | $29.7M | ||
| Q1 24 | $-4.8M | $30.7M |
| Q4 25 | 69.3% | 98.6% | ||
| Q3 25 | 77.7% | 98.5% | ||
| Q2 25 | 76.5% | 99.1% | ||
| Q1 25 | 77.1% | 98.8% | ||
| Q4 24 | 76.4% | 98.8% | ||
| Q3 24 | 63.9% | 98.8% | ||
| Q2 24 | 77.4% | 98.8% | ||
| Q1 24 | 75.5% | 98.8% |
| Q4 25 | 22.7% | 27.4% | ||
| Q3 25 | 17.6% | 25.9% | ||
| Q2 25 | 12.7% | 25.5% | ||
| Q1 25 | 8.7% | 25.9% | ||
| Q4 24 | 22.6% | 24.6% | ||
| Q3 24 | 27.4% | 17.5% | ||
| Q2 24 | -4.6% | 26.7% | ||
| Q1 24 | -5.3% | 26.4% |
| Q4 25 | — | 28.5% | ||
| Q3 25 | 16.2% | 30.5% | ||
| Q2 25 | 11.2% | 29.8% | ||
| Q1 25 | 6.5% | 30.1% | ||
| Q4 24 | — | 28.3% | ||
| Q3 24 | 25.2% | 21.3% | ||
| Q2 24 | -9.6% | 33.0% | ||
| Q1 24 | -11.0% | 33.0% |
| Q4 25 | $0.26 | $0.38 | ||
| Q3 25 | $0.17 | $0.41 | ||
| Q2 25 | $0.12 | $0.39 | ||
| Q1 25 | $0.06 | $0.41 | ||
| Q4 24 | $0.40 | $0.36 | ||
| Q3 24 | $0.41 | $0.27 | ||
| Q2 24 | $-0.09 | $0.42 | ||
| Q1 24 | $-0.10 | $0.43 |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $97.5M | $21.7M |
| Total DebtLower is stronger | $22.7M | $4.6B |
| Stockholders' EquityBook value | $130.3M | $2.4B |
| Total Assets | $216.3M | $7.2B |
| Debt / EquityLower = less leverage | 0.17× | 1.90× |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $97.5M | $21.7M | ||
| Q3 25 | $94.4M | $12.1M | ||
| Q2 25 | $96.0M | $13.9M | ||
| Q1 25 | $93.2M | $17.3M | ||
| Q4 24 | $101.0M | $8.3M | ||
| Q3 24 | $96.7M | $15.6M | ||
| Q2 24 | $96.8M | $13.4M | ||
| Q1 24 | $107.2M | $11.3M |
| Q4 25 | $22.7M | $4.6B | ||
| Q3 25 | $34.0M | $4.5B | ||
| Q2 25 | $45.3M | $4.4B | ||
| Q1 25 | $56.7M | $4.3B | ||
| Q4 24 | $68.0M | $4.3B | ||
| Q3 24 | $79.3M | $4.3B | ||
| Q2 24 | $90.7M | $4.2B | ||
| Q1 24 | $102.0M | $4.1B |
| Q4 25 | $130.3M | $2.4B | ||
| Q3 25 | $115.3M | $2.4B | ||
| Q2 25 | $104.7M | $2.4B | ||
| Q1 25 | $97.1M | $2.4B | ||
| Q4 24 | $92.1M | $2.3B | ||
| Q3 24 | $71.1M | $2.3B | ||
| Q2 24 | $48.5M | $2.3B | ||
| Q1 24 | $51.0M | $2.3B |
| Q4 25 | $216.3M | $7.2B | ||
| Q3 25 | $202.9M | $7.1B | ||
| Q2 25 | $194.9M | $7.1B | ||
| Q1 25 | $196.2M | $6.9B | ||
| Q4 24 | $213.3M | $6.9B | ||
| Q3 24 | $220.7M | $6.8B | ||
| Q2 24 | $205.0M | $6.8B | ||
| Q1 24 | $214.1M | $6.7B |
| Q4 25 | 0.17× | 1.90× | ||
| Q3 25 | 0.30× | 1.89× | ||
| Q2 25 | 0.43× | 1.87× | ||
| Q1 25 | 0.58× | 1.85× | ||
| Q4 24 | 0.74× | 1.84× | ||
| Q3 24 | 1.12× | 1.88× | ||
| Q2 24 | 1.87× | 1.81× | ||
| Q1 24 | 2.00× | 1.81× |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | $14.4M | $47.8M |
| Free Cash FlowOCF − Capex | $14.4M | — |
| FCF MarginFCF / Revenue | 19.1% | — |
| Capex IntensityCapex / Revenue | 0.0% | — |
| Cash ConversionOCF / Net Profit | — | 1.72× |
| TTM Free Cash FlowTrailing 4 quarters | $41.7M | — |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $14.4M | $47.8M | ||
| Q3 25 | $9.7M | $-1.4M | ||
| Q2 25 | $14.1M | $28.0M | ||
| Q1 25 | $3.6M | $8.9M | ||
| Q4 24 | $15.6M | $37.9M | ||
| Q3 24 | $11.0M | $8.3M | ||
| Q2 24 | $1.0M | $24.8M | ||
| Q1 24 | $11.2M | $-3.1M |
| Q4 25 | $14.4M | — | ||
| Q3 25 | $9.7M | — | ||
| Q2 25 | $14.1M | — | ||
| Q1 25 | $3.6M | — | ||
| Q4 24 | $15.6M | — | ||
| Q3 24 | $11.0M | — | ||
| Q2 24 | $1.0M | — | ||
| Q1 24 | — | — |
| Q4 25 | 19.1% | — | ||
| Q3 25 | 17.7% | — | ||
| Q2 25 | 26.8% | — | ||
| Q1 25 | 7.7% | — | ||
| Q4 24 | 26.4% | — | ||
| Q3 24 | 13.7% | — | ||
| Q2 24 | 2.1% | — | ||
| Q1 24 | — | — |
| Q4 25 | 0.0% | — | ||
| Q3 25 | 0.0% | — | ||
| Q2 25 | 0.0% | — | ||
| Q1 25 | 0.1% | — | ||
| Q4 24 | 0.0% | — | ||
| Q3 24 | 0.0% | — | ||
| Q2 24 | 0.0% | — | ||
| Q1 24 | 0.0% | — |
| Q4 25 | — | 1.72× | ||
| Q3 25 | 1.10× | -0.05× | ||
| Q2 25 | 2.41× | 1.00× | ||
| Q1 25 | 1.21× | 0.30× | ||
| Q4 24 | — | 1.45× | ||
| Q3 24 | 0.54× | 0.43× | ||
| Q2 24 | — | 0.83× | ||
| Q1 24 | — | -0.10× |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
Revenue Breakdown by Segment
PBYI
Segment breakdown not available.
SAFE
| Equity Method Investment Nonconsolidated Investee Or Group Of Investees | $60.3M | 62% |
| Other | $33.7M | 34% |
| Stabilized Properties | $3.8M | 4% |
