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Side-by-side financial comparison of PIPER SANDLER COMPANIES (PIPR) and Sarepta Therapeutics, Inc. (SRPT). Click either name above to swap in a different company.

PIPER SANDLER COMPANIES is the larger business by last-quarter revenue ($667.0M vs $369.6M, roughly 1.8× Sarepta Therapeutics, Inc.). PIPER SANDLER COMPANIES runs the higher net margin — 17.1% vs -111.5%, a 128.6% gap on every dollar of revenue. On growth, PIPER SANDLER COMPANIES posted the faster year-over-year revenue change (37.4% vs -42.1%). Over the past eight quarters, PIPER SANDLER COMPANIES's revenue compounded faster (39.2% CAGR vs 1.4%).

Piper Sandler Companies is an American multinational investment bank and financial services company, focused on mergers and acquisitions, financial restructuring, public offerings, public finance, institutional brokerage, investment management, and securities research. Through its principal subsidiary, Piper Sandler & Co., the company targets corporations, institutional investors, and public entities.

Sarepta Therapeutics, Inc. is a medical research and drug development company with corporate offices and research facilities in Cambridge, Massachusetts, United States. Incorporated in 1980 as AntiVirals, shortly before going public the company changed its name from AntiVirals to AVI BioPharma soon with stock symbol AVII and in July 2012 changed name from AVI BioPharma to Sarepta Therapeutics and SRPT respectively. As of 2023, the company has four approved drugs.

PIPR vs SRPT — Head-to-Head

Bigger by revenue
PIPR
PIPR
1.8× larger
PIPR
$667.0M
$369.6M
SRPT
Growing faster (revenue YoY)
PIPR
PIPR
+79.5% gap
PIPR
37.4%
-42.1%
SRPT
Higher net margin
PIPR
PIPR
128.6% more per $
PIPR
17.1%
-111.5%
SRPT
Faster 2-yr revenue CAGR
PIPR
PIPR
Annualised
PIPR
39.2%
1.4%
SRPT

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
PIPR
PIPR
SRPT
SRPT
Revenue
$667.0M
$369.6M
Net Profit
$114.0M
$-412.2M
Gross Margin
Operating Margin
28.3%
-111.4%
Net Margin
17.1%
-111.5%
Revenue YoY
37.4%
-42.1%
Net Profit YoY
65.0%
-359.2%
EPS (diluted)
$6.41
$-3.92

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
PIPR
PIPR
SRPT
SRPT
Q4 25
$667.0M
$369.6M
Q3 25
$480.1M
$370.0M
Q2 25
$398.6M
$513.1M
Q1 25
$358.6M
$611.5M
Q4 24
$485.4M
$638.2M
Q3 24
$360.9M
$429.8M
Q2 24
$340.8M
$360.5M
Q1 24
$344.4M
$359.5M
Net Profit
PIPR
PIPR
SRPT
SRPT
Q4 25
$114.0M
$-412.2M
Q3 25
$60.3M
$-50.6M
Q2 25
$42.2M
$196.9M
Q1 25
$64.9M
$-447.5M
Q4 24
$69.1M
$159.0M
Q3 24
$34.8M
$33.6M
Q2 24
$34.8M
$6.5M
Q1 24
$42.5M
$36.1M
Gross Margin
PIPR
PIPR
SRPT
SRPT
Q4 25
Q3 25
59.3%
Q2 25
70.3%
Q1 25
77.5%
Q4 24
Q3 24
78.7%
Q2 24
87.6%
Q1 24
85.9%
Operating Margin
PIPR
PIPR
SRPT
SRPT
Q4 25
28.3%
-111.4%
Q3 25
22.4%
-27.9%
Q2 25
12.3%
22.5%
Q1 25
8.2%
-49.1%
Q4 24
16.9%
25.3%
Q3 24
15.4%
5.2%
Q2 24
8.3%
-0.2%
Q1 24
15.2%
9.7%
Net Margin
PIPR
PIPR
SRPT
SRPT
Q4 25
17.1%
-111.5%
Q3 25
12.6%
-13.7%
Q2 25
10.6%
38.4%
Q1 25
18.1%
-73.2%
Q4 24
14.2%
24.9%
Q3 24
9.6%
7.8%
Q2 24
10.2%
1.8%
Q1 24
12.3%
10.0%
EPS (diluted)
PIPR
PIPR
SRPT
SRPT
Q4 25
$6.41
$-3.92
Q3 25
$3.38
$-0.50
Q2 25
$2.38
$1.89
Q1 25
$3.65
$-4.60
Q4 24
$3.88
$1.56
Q3 24
$1.96
$0.34
Q2 24
$1.97
$0.07
Q1 24
$2.43
$0.37

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
PIPR
PIPR
SRPT
SRPT
Cash + ST InvestmentsLiquidity on hand
$939.6M
Total DebtLower is stronger
$829.0M
Stockholders' EquityBook value
$1.4B
$1.1B
Total Assets
$2.6B
$3.3B
Debt / EquityLower = less leverage
0.73×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
PIPR
PIPR
SRPT
SRPT
Q4 25
$939.6M
Q3 25
$851.0M
Q2 25
$800.1M
Q1 25
$522.8M
Q4 24
$1.4B
Q3 24
$1.2B
Q2 24
$1.5B
Q1 24
$1.4B
Total Debt
PIPR
PIPR
SRPT
SRPT
Q4 25
$829.0M
Q3 25
$140.5M
Q2 25
Q1 25
Q4 24
$1.1B
Q3 24
$1.2B
Q2 24
$1.2B
Q1 24
$1.2B
Stockholders' Equity
PIPR
PIPR
SRPT
SRPT
Q4 25
$1.4B
$1.1B
Q3 25
$1.3B
$1.3B
Q2 25
$1.2B
$1.4B
Q1 25
$1.2B
$1.1B
Q4 24
$1.2B
$1.5B
Q3 24
$1.2B
$1.2B
Q2 24
$1.1B
$1.1B
Q1 24
$1.1B
$961.2M
Total Assets
PIPR
PIPR
SRPT
SRPT
Q4 25
$2.6B
$3.3B
Q3 25
$2.2B
$3.5B
Q2 25
$2.0B
$3.7B
Q1 25
$1.8B
$3.5B
Q4 24
$2.3B
$4.0B
Q3 24
$2.0B
$3.6B
Q2 24
$1.9B
$3.4B
Q1 24
$1.8B
$3.2B
Debt / Equity
PIPR
PIPR
SRPT
SRPT
Q4 25
0.73×
Q3 25
0.11×
Q2 25
Q1 25
Q4 24
0.74×
Q3 24
1.01×
Q2 24
1.14×
Q1 24
1.29×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
PIPR
PIPR
SRPT
SRPT
Operating Cash FlowLast quarter
$729.8M
$131.2M
Free Cash FlowOCF − Capex
$127.6M
FCF MarginFCF / Revenue
34.5%
Capex IntensityCapex / Revenue
1.0%
Cash ConversionOCF / Net Profit
6.40×
TTM Free Cash FlowTrailing 4 quarters
$-307.5M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
PIPR
PIPR
SRPT
SRPT
Q4 25
$729.8M
$131.2M
Q3 25
$31.9M
$-14.6M
Q2 25
$32.1M
$261.3M
Q1 25
$-207.2M
$-583.4M
Q4 24
$163.8M
$92.0M
Q3 24
$80.1M
$-70.7M
Q2 24
$266.5M
$14.9M
Q1 24
$-197.2M
$-242.1M
Free Cash Flow
PIPR
PIPR
SRPT
SRPT
Q4 25
$127.6M
Q3 25
$-37.5M
Q2 25
$229.5M
Q1 25
$-627.1M
Q4 24
$54.0M
Q3 24
$-108.0M
Q2 24
$-14.2M
Q1 24
$-274.5M
FCF Margin
PIPR
PIPR
SRPT
SRPT
Q4 25
34.5%
Q3 25
-10.1%
Q2 25
44.7%
Q1 25
-102.5%
Q4 24
8.5%
Q3 24
-25.1%
Q2 24
-3.9%
Q1 24
-76.4%
Capex Intensity
PIPR
PIPR
SRPT
SRPT
Q4 25
1.0%
Q3 25
6.2%
Q2 25
6.2%
Q1 25
7.1%
Q4 24
6.0%
Q3 24
8.7%
Q2 24
8.1%
Q1 24
9.0%
Cash Conversion
PIPR
PIPR
SRPT
SRPT
Q4 25
6.40×
Q3 25
0.53×
Q2 25
0.76×
1.33×
Q1 25
-3.19×
Q4 24
2.37×
0.58×
Q3 24
2.30×
-2.10×
Q2 24
7.66×
2.31×
Q1 24
-4.64×
-6.70×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

PIPR
PIPR

Advisory Services$402.6M60%
Equities Financing$66.7M10%
Equity Salesand Trading$64.2M10%
Fixed Income Salesand Trading$47.9M7%
Other$46.7M7%
Debt Financing$38.9M6%

SRPT
SRPT

Pmo Products$202.5M55%
Elevidys$110.4M30%
Other$56.7M15%

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