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Side-by-side financial comparison of PROASSURANCE CORP (PRA) and REPLIGEN CORP (RGEN). Click either name above to swap in a different company.

PROASSURANCE CORP is the larger business by last-quarter revenue ($269.6M vs $197.9M, roughly 1.4× REPLIGEN CORP). PROASSURANCE CORP runs the higher net margin — 12.4% vs 6.7%, a 5.7% gap on every dollar of revenue. On growth, REPLIGEN CORP posted the faster year-over-year revenue change (13.6% vs -7.1%). Over the past eight quarters, REPLIGEN CORP's revenue compounded faster (14.4% CAGR vs -2.7%).

ProAssurance Corporation, headquartered in Birmingham, Alabama, is a property and casualty company that sells professional liability insurance to doctors. The company was founded in 1976 as Mutual Assurance and was later renamed to Medical Assurance in 1997. The name "ProAssurance" was created in 2001 when Medical Assurance merged with Professionals Group. The company is currently the fourth largest medical professional liability insurance writer and has over $6 billion in assets.

Repligen Corporation is a global life sciences company devoted to the development and commercialization of innovative bioprocessing technologies and systems that enable efficiencies in the process of manufacturing biological drugs.2025 The company is based in Waltham, Massachusetts,2014 and was incorporated in Delaware in 1981. A public company, Repligen is listed on the NASDAQ exchange under the symbol RGEN. As of 2025, Repligen employs over 1,900 employees globally and serves primarily biop...

PRA vs RGEN — Head-to-Head

Bigger by revenue
PRA
PRA
1.4× larger
PRA
$269.6M
$197.9M
RGEN
Growing faster (revenue YoY)
RGEN
RGEN
+20.7% gap
RGEN
13.6%
-7.1%
PRA
Higher net margin
PRA
PRA
5.7% more per $
PRA
12.4%
6.7%
RGEN
Faster 2-yr revenue CAGR
RGEN
RGEN
Annualised
RGEN
14.4%
-2.7%
PRA

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
PRA
PRA
RGEN
RGEN
Revenue
$269.6M
$197.9M
Net Profit
$33.4M
$13.3M
Gross Margin
52.5%
Operating Margin
17.3%
9.0%
Net Margin
12.4%
6.7%
Revenue YoY
-7.1%
13.6%
Net Profit YoY
106.4%
143.9%
EPS (diluted)
$0.65
$0.24

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
PRA
PRA
RGEN
RGEN
Q4 25
$269.6M
$197.9M
Q3 25
$279.6M
$188.8M
Q2 25
$276.8M
$182.4M
Q1 25
$272.1M
$169.2M
Q4 24
$290.1M
$174.1M
Q3 24
$285.3M
$154.9M
Q2 24
$290.4M
$154.1M
Q1 24
$284.7M
$151.3M
Net Profit
PRA
PRA
RGEN
RGEN
Q4 25
$33.4M
$13.3M
Q3 25
$1.4M
$14.9M
Q2 25
$21.9M
$14.9M
Q1 25
$-5.8M
$5.8M
Q4 24
$16.2M
$-30.3M
Q3 24
$16.4M
$-654.0K
Q2 24
$15.5M
$3.3M
Q1 24
$4.6M
$2.1M
Gross Margin
PRA
PRA
RGEN
RGEN
Q4 25
52.5%
Q3 25
53.2%
Q2 25
50.0%
Q1 25
53.6%
Q4 24
26.1%
Q3 24
50.0%
Q2 24
49.8%
Q1 24
49.5%
Operating Margin
PRA
PRA
RGEN
RGEN
Q4 25
17.3%
9.0%
Q3 25
1.6%
8.9%
Q2 25
9.9%
7.6%
Q1 25
-2.3%
3.9%
Q4 24
6.5%
-17.7%
Q3 24
7.4%
-5.1%
Q2 24
6.2%
1.0%
Q1 24
1.9%
1.3%
Net Margin
PRA
PRA
RGEN
RGEN
Q4 25
12.4%
6.7%
Q3 25
0.5%
7.9%
Q2 25
7.9%
8.2%
Q1 25
-2.1%
3.4%
Q4 24
5.6%
-17.4%
Q3 24
5.8%
-0.4%
Q2 24
5.3%
2.2%
Q1 24
1.6%
1.4%
EPS (diluted)
PRA
PRA
RGEN
RGEN
Q4 25
$0.65
$0.24
Q3 25
$0.03
$0.26
Q2 25
$0.42
$0.26
Q1 25
$-0.11
$0.10
Q4 24
$0.32
$-0.55
Q3 24
$0.32
$-0.01
Q2 24
$0.30
$0.06
Q1 24
$0.09
$0.04

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
PRA
PRA
RGEN
RGEN
Cash + ST InvestmentsLiquidity on hand
$36.5M
$767.6M
Total DebtLower is stronger
$420.4M
$542.2M
Stockholders' EquityBook value
$1.3B
$2.1B
Total Assets
$5.4B
$2.9B
Debt / EquityLower = less leverage
0.31×
0.26×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
PRA
PRA
RGEN
RGEN
Q4 25
$36.5M
$767.6M
Q3 25
$54.5M
$748.7M
Q2 25
$41.6M
$708.9M
Q1 25
$43.5M
$697.2M
Q4 24
$54.9M
$757.4M
Q3 24
$45.3M
$784.0M
Q2 24
$36.9M
$809.1M
Q1 24
$65.4M
$780.6M
Total Debt
PRA
PRA
RGEN
RGEN
Q4 25
$420.4M
$542.2M
Q3 25
$421.5M
$537.9M
Q2 25
$422.6M
Q1 25
$423.7M
Q4 24
$424.9M
$525.6M
Q3 24
$425.9M
Q2 24
$426.9M
Q1 24
$427.8M
Stockholders' Equity
PRA
PRA
RGEN
RGEN
Q4 25
$1.3B
$2.1B
Q3 25
$1.3B
$2.1B
Q2 25
$1.3B
$2.1B
Q1 25
$1.2B
$2.0B
Q4 24
$1.2B
$2.0B
Q3 24
$1.2B
$2.0B
Q2 24
$1.1B
$2.0B
Q1 24
$1.1B
$2.0B
Total Assets
PRA
PRA
RGEN
RGEN
Q4 25
$5.4B
$2.9B
Q3 25
$5.6B
$2.9B
Q2 25
$5.5B
$2.9B
Q1 25
$5.5B
$2.9B
Q4 24
$5.6B
$2.8B
Q3 24
$5.7B
$2.8B
Q2 24
$5.6B
$2.9B
Q1 24
$5.7B
$2.8B
Debt / Equity
PRA
PRA
RGEN
RGEN
Q4 25
0.31×
0.26×
Q3 25
0.32×
0.26×
Q2 25
0.33×
Q1 25
0.34×
Q4 24
0.35×
0.27×
Q3 24
0.35×
Q2 24
0.38×
Q1 24
0.38×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
PRA
PRA
RGEN
RGEN
Operating Cash FlowLast quarter
$-25.6M
$25.7M
Free Cash FlowOCF − Capex
$17.6M
FCF MarginFCF / Revenue
8.9%
Capex IntensityCapex / Revenue
4.1%
Cash ConversionOCF / Net Profit
-0.77×
1.93×
TTM Free Cash FlowTrailing 4 quarters
$93.9M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
PRA
PRA
RGEN
RGEN
Q4 25
$-25.6M
$25.7M
Q3 25
$27.2M
$48.1M
Q2 25
$-28.1M
$28.6M
Q1 25
$-11.6M
$15.0M
Q4 24
$-10.7M
$39.2M
Q3 24
$14.0M
$49.3M
Q2 24
$-12.8M
$42.2M
Q1 24
$-11.6M
$44.7M
Free Cash Flow
PRA
PRA
RGEN
RGEN
Q4 25
$17.6M
Q3 25
$43.4M
Q2 25
$21.5M
Q1 25
$11.4M
Q4 24
$33.6M
Q3 24
$42.3M
Q2 24
$37.4M
Q1 24
$36.4M
FCF Margin
PRA
PRA
RGEN
RGEN
Q4 25
8.9%
Q3 25
23.0%
Q2 25
11.8%
Q1 25
6.8%
Q4 24
19.3%
Q3 24
27.3%
Q2 24
24.3%
Q1 24
24.0%
Capex Intensity
PRA
PRA
RGEN
RGEN
Q4 25
4.1%
Q3 25
2.5%
Q2 25
3.9%
Q1 25
2.1%
Q4 24
3.2%
Q3 24
4.5%
Q2 24
3.1%
Q1 24
5.5%
Cash Conversion
PRA
PRA
RGEN
RGEN
Q4 25
-0.77×
1.93×
Q3 25
18.81×
3.23×
Q2 25
-1.28×
1.92×
Q1 25
2.57×
Q4 24
-0.66×
Q3 24
0.85×
Q2 24
-0.83×
12.70×
Q1 24
-2.52×
21.35×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

PRA
PRA

Workers Compensation Insurance Segment$164.4M61%
Other$59.6M22%
Segregated Portfolio Cell Reinsurance$45.7M17%

RGEN
RGEN

Segment breakdown not available.

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