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Side-by-side financial comparison of Prime Medicine, Inc. (PRME) and Power REIT (PW). Click either name above to swap in a different company.
Prime Medicine, Inc. is the larger business by last-quarter revenue ($838.0K vs $506.1K, roughly 1.7× Power REIT). Power REIT runs the higher net margin — -262.1% vs -5498.7%, a 5236.6% gap on every dollar of revenue. On growth, Power REIT posted the faster year-over-year revenue change (-11.2% vs -61.6%).
Prime Medicine, Inc. is an American biotechnology company developing gene therapies based on prime editing. The company is headquartered in Cambridge, Massachusetts.
H&R Real Estate Investment Trust is a Canadian open-ended real estate investment trust, specializing in commercial real estate, and based in Toronto, Ontario. It is the eighth largest REIT in Canada by market capitalization, following its 2021 strategic review, which included the sale of its Bow office tower and spin-off of Primaris REIT. H&R's portfolio spans 25.6 million sq.ft., 70% by value located in the United States and 49% focused on multi-residential properties, with the remainder inc...
PRME vs PW — Head-to-Head
Income Statement — Q4 FY2025 vs Q4 FY2025
| Metric | | |
|---|---|---|
| Revenue | $838.0K | $506.1K |
| Net Profit | $-46.1M | $-1.3M |
| Gross Margin | — | — |
| Operating Margin | -5800.5% | — |
| Net Margin | -5498.7% | -262.1% |
| Revenue YoY | -61.6% | -11.2% |
| Net Profit YoY | -9.0% | 58.1% |
| EPS (diluted) | $-0.22 | $-0.43 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q4 25 | $838.0K | $506.1K | ||
| Q3 25 | $1.2M | $513.1K | ||
| Q2 25 | $1.1M | $506.8K | ||
| Q1 25 | $1.5M | $485.8K | ||
| Q4 24 | $2.2M | $569.8K | ||
| Q3 24 | — | $1.4M | ||
| Q2 24 | $0 | $519.3K | ||
| Q1 24 | $591.0K | $534.6K |
| Q4 25 | $-46.1M | $-1.3M | ||
| Q3 25 | $-50.6M | $223.6K | ||
| Q2 25 | $-52.6M | $320.9K | ||
| Q1 25 | $-51.9M | $-1.4M | ||
| Q4 24 | $-42.3M | $-3.2M | ||
| Q3 24 | — | $-325.0K | ||
| Q2 24 | $-55.3M | $-19.1M | ||
| Q1 24 | $-45.8M | $-2.1M |
| Q4 25 | -5800.5% | — | ||
| Q3 25 | -4406.0% | — | ||
| Q2 25 | -4787.2% | — | ||
| Q1 25 | -3603.3% | — | ||
| Q4 24 | -2025.7% | — | ||
| Q3 24 | — | — | ||
| Q2 24 | — | — | ||
| Q1 24 | -8179.5% | — |
| Q4 25 | -5498.7% | -262.1% | ||
| Q3 25 | -4129.1% | 43.6% | ||
| Q2 25 | -4716.7% | 63.3% | ||
| Q1 25 | -3568.8% | -290.9% | ||
| Q4 24 | -1936.6% | -555.2% | ||
| Q3 24 | — | -22.8% | ||
| Q2 24 | — | -3686.4% | ||
| Q1 24 | -7743.0% | -388.5% |
| Q4 25 | $-0.22 | $-0.43 | ||
| Q3 25 | $-0.32 | $0.02 | ||
| Q2 25 | $-0.41 | $0.05 | ||
| Q1 25 | $-0.40 | $-0.47 | ||
| Q4 24 | $-0.31 | $-0.98 | ||
| Q3 24 | — | $-0.14 | ||
| Q2 24 | $-0.46 | $-5.70 | ||
| Q1 24 | $-0.44 | $-0.66 |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $63.0M | $2.2M |
| Total DebtLower is stronger | — | $20.4M |
| Stockholders' EquityBook value | $120.9M | $5.1M |
| Total Assets | $342.7M | $26.9M |
| Debt / EquityLower = less leverage | — | 3.97× |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $63.0M | $2.2M | ||
| Q3 25 | $71.4M | $2.0M | ||
| Q2 25 | $53.8M | $1.5M | ||
| Q1 25 | $91.9M | $2.0M | ||
| Q4 24 | $182.5M | $2.2M | ||
| Q3 24 | — | $2.2M | ||
| Q2 24 | $55.6M | $2.5M | ||
| Q1 24 | $94.2M | $3.0M |
| Q4 25 | — | $20.4M | ||
| Q3 25 | — | $20.5M | ||
| Q2 25 | — | $20.9M | ||
| Q1 25 | — | $38.8M | ||
| Q4 24 | — | $37.9M | ||
| Q3 24 | — | $37.5M | ||
| Q2 24 | — | $37.4M | ||
| Q1 24 | — | $36.2M |
| Q4 25 | $120.9M | $5.1M | ||
| Q3 25 | $161.8M | $6.2M | ||
| Q2 25 | $60.9M | $5.9M | ||
| Q1 25 | $106.9M | $5.5M | ||
| Q4 24 | $153.1M | $6.8M | ||
| Q3 24 | — | $9.8M | ||
| Q2 24 | $196.6M | $10.0M | ||
| Q1 24 | $243.8M | $28.9M |
| Q4 25 | $342.7M | $26.9M | ||
| Q3 25 | $385.0M | $28.0M | ||
| Q2 25 | $279.0M | $27.9M | ||
| Q1 25 | $328.2M | $45.6M | ||
| Q4 24 | $297.5M | $46.1M | ||
| Q3 24 | — | $48.4M | ||
| Q2 24 | $259.7M | $49.8M | ||
| Q1 24 | $311.4M | $68.9M |
| Q4 25 | — | 3.97× | ||
| Q3 25 | — | 3.30× | ||
| Q2 25 | — | 3.51× | ||
| Q1 25 | — | 7.07× | ||
| Q4 24 | — | 5.61× | ||
| Q3 24 | — | 3.84× | ||
| Q2 24 | — | 3.76× | ||
| Q1 24 | — | 1.25× |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | $-37.3M | $-68.3K |
| Free Cash FlowOCF − Capex | $-37.5M | — |
| FCF MarginFCF / Revenue | -4480.4% | — |
| Capex IntensityCapex / Revenue | 34.6% | — |
| Cash ConversionOCF / Net Profit | — | — |
| TTM Free Cash FlowTrailing 4 quarters | $-167.1M | — |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $-37.3M | $-68.3K | ||
| Q3 25 | $-35.0M | $476.4K | ||
| Q2 25 | $-41.4M | $-240.5K | ||
| Q1 25 | $-48.9M | $-436.6K | ||
| Q4 24 | $16.2M | $-1.4M | ||
| Q3 24 | — | $-161.8K | ||
| Q2 24 | $-45.5M | $-541.5K | ||
| Q1 24 | $-67.7M | $-402.2K |
| Q4 25 | $-37.5M | — | ||
| Q3 25 | $-35.3M | — | ||
| Q2 25 | $-43.0M | — | ||
| Q1 25 | $-51.3M | — | ||
| Q4 24 | $14.5M | — | ||
| Q3 24 | — | — | ||
| Q2 24 | $-47.4M | — | ||
| Q1 24 | $-70.0M | — |
| Q4 25 | -4480.4% | — | ||
| Q3 25 | -2880.5% | — | ||
| Q2 25 | -3855.1% | — | ||
| Q1 25 | -3526.8% | — | ||
| Q4 24 | 662.1% | — | ||
| Q3 24 | — | — | ||
| Q2 24 | — | — | ||
| Q1 24 | -11849.6% | — |
| Q4 25 | 34.6% | — | ||
| Q3 25 | 20.2% | — | ||
| Q2 25 | 141.0% | — | ||
| Q1 25 | 166.6% | — | ||
| Q4 24 | 82.0% | — | ||
| Q3 24 | — | — | ||
| Q2 24 | — | — | ||
| Q1 24 | 393.2% | — |
| Q4 25 | — | — | ||
| Q3 25 | — | 2.13× | ||
| Q2 25 | — | -0.75× | ||
| Q1 25 | — | — | ||
| Q4 24 | — | — | ||
| Q3 24 | — | — | ||
| Q2 24 | — | — | ||
| Q1 24 | — | — |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
