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Side-by-side financial comparison of Prime Medicine, Inc. (PRME) and ReTo Eco-Solutions, Inc. (RETO). Click either name above to swap in a different company.

ReTo Eco-Solutions, Inc. is the larger business by last-quarter revenue ($1.0M vs $838.0K, roughly 1.3× Prime Medicine, Inc.). ReTo Eco-Solutions, Inc. runs the higher net margin — -131.6% vs -5498.7%, a 5367.1% gap on every dollar of revenue. On growth, ReTo Eco-Solutions, Inc. posted the faster year-over-year revenue change (36.6% vs -61.6%). ReTo Eco-Solutions, Inc. produced more free cash flow last quarter ($-1.7M vs $-37.5M).

Prime Medicine, Inc. is an American biotechnology company developing gene therapies based on prime editing. The company is headquartered in Cambridge, Massachusetts.

ReTo Eco-Solutions, Inc. develops and supplies eco-friendly construction materials, environmental remediation services, and solid waste treatment solutions. Its core offerings include recycled construction aggregates, soil improvement products, and ecological restoration systems, primarily serving infrastructure, real estate, and environmental conservation sectors across the Chinese market.

PRME vs RETO — Head-to-Head

Bigger by revenue
RETO
RETO
1.3× larger
RETO
$1.0M
$838.0K
PRME
Growing faster (revenue YoY)
RETO
RETO
+98.2% gap
RETO
36.6%
-61.6%
PRME
Higher net margin
RETO
RETO
5367.1% more per $
RETO
-131.6%
-5498.7%
PRME
More free cash flow
RETO
RETO
$35.9M more FCF
RETO
$-1.7M
$-37.5M
PRME

Income Statement — Q4 FY2025 vs Q2 FY2025

Metric
PRME
PRME
RETO
RETO
Revenue
$838.0K
$1.0M
Net Profit
$-46.1M
$-1.4M
Gross Margin
17.7%
Operating Margin
-5800.5%
-133.0%
Net Margin
-5498.7%
-131.6%
Revenue YoY
-61.6%
36.6%
Net Profit YoY
-9.0%
-103.5%
EPS (diluted)
$-0.22

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
PRME
PRME
RETO
RETO
Q4 25
$838.0K
Q3 25
$1.2M
Q2 25
$1.1M
$1.0M
Q1 25
$1.5M
Q4 24
$2.2M
Q2 24
$0
$768.4K
Q1 24
$591.0K
Q4 23
$0
Net Profit
PRME
PRME
RETO
RETO
Q4 25
$-46.1M
Q3 25
$-50.6M
Q2 25
$-52.6M
$-1.4M
Q1 25
$-51.9M
Q4 24
$-42.3M
Q2 24
$-55.3M
$-678.5K
Q1 24
$-45.8M
Q4 23
$-65.6M
Gross Margin
PRME
PRME
RETO
RETO
Q4 25
Q3 25
Q2 25
17.7%
Q1 25
Q4 24
Q2 24
43.3%
Q1 24
Q4 23
Operating Margin
PRME
PRME
RETO
RETO
Q4 25
-5800.5%
Q3 25
-4406.0%
Q2 25
-4787.2%
-133.0%
Q1 25
-3603.3%
Q4 24
-2025.7%
Q2 24
-68.0%
Q1 24
-8179.5%
Q4 23
Net Margin
PRME
PRME
RETO
RETO
Q4 25
-5498.7%
Q3 25
-4129.1%
Q2 25
-4716.7%
-131.6%
Q1 25
-3568.8%
Q4 24
-1936.6%
Q2 24
-88.3%
Q1 24
-7743.0%
Q4 23
EPS (diluted)
PRME
PRME
RETO
RETO
Q4 25
$-0.22
Q3 25
$-0.32
Q2 25
$-0.41
Q1 25
$-0.40
Q4 24
$-0.31
Q2 24
$-0.46
$-0.25
Q1 24
$-0.44
Q4 23
$-0.72

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
PRME
PRME
RETO
RETO
Cash + ST InvestmentsLiquidity on hand
$63.0M
$2.5M
Total DebtLower is stronger
Stockholders' EquityBook value
$120.9M
$30.4M
Total Assets
$342.7M
$41.4M
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
PRME
PRME
RETO
RETO
Q4 25
$63.0M
Q3 25
$71.4M
Q2 25
$53.8M
$2.5M
Q1 25
$91.9M
Q4 24
$182.5M
Q2 24
$55.6M
$1.6M
Q1 24
$94.2M
Q4 23
$41.6M
Stockholders' Equity
PRME
PRME
RETO
RETO
Q4 25
$120.9M
Q3 25
$161.8M
Q2 25
$60.9M
$30.4M
Q1 25
$106.9M
Q4 24
$153.1M
Q2 24
$196.6M
$13.3M
Q1 24
$243.8M
Q4 23
$133.1M
Total Assets
PRME
PRME
RETO
RETO
Q4 25
$342.7M
Q3 25
$385.0M
Q2 25
$279.0M
$41.4M
Q1 25
$328.2M
Q4 24
$297.5M
Q2 24
$259.7M
$33.7M
Q1 24
$311.4M
Q4 23
$193.9M

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
PRME
PRME
RETO
RETO
Operating Cash FlowLast quarter
$-37.3M
$-1.6M
Free Cash FlowOCF − Capex
$-37.5M
$-1.7M
FCF MarginFCF / Revenue
-4480.4%
-157.4%
Capex IntensityCapex / Revenue
34.6%
5.1%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$-167.1M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
PRME
PRME
RETO
RETO
Q4 25
$-37.3M
Q3 25
$-35.0M
Q2 25
$-41.4M
$-1.6M
Q1 25
$-48.9M
Q4 24
$16.2M
Q2 24
$-45.5M
$-4.8M
Q1 24
$-67.7M
Q4 23
$-43.9M
Free Cash Flow
PRME
PRME
RETO
RETO
Q4 25
$-37.5M
Q3 25
$-35.3M
Q2 25
$-43.0M
$-1.7M
Q1 25
$-51.3M
Q4 24
$14.5M
Q2 24
$-47.4M
Q1 24
$-70.0M
Q4 23
$-45.7M
FCF Margin
PRME
PRME
RETO
RETO
Q4 25
-4480.4%
Q3 25
-2880.5%
Q2 25
-3855.1%
-157.4%
Q1 25
-3526.8%
Q4 24
662.1%
Q2 24
Q1 24
-11849.6%
Q4 23
Capex Intensity
PRME
PRME
RETO
RETO
Q4 25
34.6%
Q3 25
20.2%
Q2 25
141.0%
5.1%
Q1 25
166.6%
Q4 24
82.0%
Q2 24
Q1 24
393.2%
Q4 23

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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