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Side-by-side financial comparison of PTC THERAPEUTICS, INC. (PTCT) and Wheels Up Experience Inc. (UP). Click either name above to swap in a different company.

Wheels Up Experience Inc. is the larger business by last-quarter revenue ($183.8M vs $164.7M, roughly 1.1× PTC THERAPEUTICS, INC.). Wheels Up Experience Inc. runs the higher net margin — -15.7% vs -82.0%, a 66.3% gap on every dollar of revenue. On growth, Wheels Up Experience Inc. posted the faster year-over-year revenue change (-10.2% vs -22.7%). PTC THERAPEUTICS, INC. produced more free cash flow last quarter ($-36.6M vs $-58.3M). Over the past eight quarters, Wheels Up Experience Inc.'s revenue compounded faster (-3.4% CAGR vs -11.5%).

PTC Therapeutics, Inc. is a US pharmaceutical company focused on the development of orally administered small molecule drugs and gene therapy which regulate gene expression by targeting post-transcriptional control (PTC) mechanisms in orphan diseases.

Wheels Up is a provider of "on demand" private aviation in the United States and one of the largest private aviation companies in the world. It was founded in 2013 by Kenny Dichter, using a membership/on-demand business model. Wheels Up members can book private aircraft from the company fleet and third-party operators using a mobile application.

PTCT vs UP — Head-to-Head

Bigger by revenue
UP
UP
1.1× larger
UP
$183.8M
$164.7M
PTCT
Growing faster (revenue YoY)
UP
UP
+12.5% gap
UP
-10.2%
-22.7%
PTCT
Higher net margin
UP
UP
66.3% more per $
UP
-15.7%
-82.0%
PTCT
More free cash flow
PTCT
PTCT
$21.6M more FCF
PTCT
$-36.6M
$-58.3M
UP
Faster 2-yr revenue CAGR
UP
UP
Annualised
UP
-3.4%
-11.5%
PTCT

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
PTCT
PTCT
UP
UP
Revenue
$164.7M
$183.8M
Net Profit
$-135.0M
$-28.9M
Gross Margin
14.3%
Operating Margin
-43.3%
-0.9%
Net Margin
-82.0%
-15.7%
Revenue YoY
-22.7%
-10.2%
Net Profit YoY
-104.8%
67.0%
EPS (diluted)
$-1.63
$-0.04

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
PTCT
PTCT
UP
UP
Q4 25
$164.7M
$183.8M
Q3 25
$211.0M
$185.5M
Q2 25
$178.9M
$189.6M
Q1 25
$1.2B
$177.5M
Q4 24
$213.2M
$204.8M
Q3 24
$196.8M
$193.9M
Q2 24
$186.7M
$196.3M
Q1 24
$210.1M
$197.1M
Net Profit
PTCT
PTCT
UP
UP
Q4 25
$-135.0M
$-28.9M
Q3 25
$15.9M
$-83.7M
Q2 25
$-64.8M
$-82.3M
Q1 25
$866.6M
$-99.3M
Q4 24
$-65.9M
$-87.5M
Q3 24
$-106.7M
$-57.7M
Q2 24
$-99.2M
$-97.0M
Q1 24
$-91.6M
$-97.4M
Gross Margin
PTCT
PTCT
UP
UP
Q4 25
14.3%
Q3 25
6.8%
Q2 25
8.3%
Q1 25
10.8%
Q4 24
13.9%
Q3 24
13.9%
Q2 24
2.3%
Q1 24
-0.6%
Operating Margin
PTCT
PTCT
UP
UP
Q4 25
-43.3%
-0.9%
Q3 25
1.4%
-33.1%
Q2 25
-19.5%
-31.4%
Q1 25
82.5%
-45.5%
Q4 24
-76.2%
-26.0%
Q3 24
-27.7%
-21.6%
Q2 24
-21.5%
-40.3%
Q1 24
-21.6%
-42.9%
Net Margin
PTCT
PTCT
UP
UP
Q4 25
-82.0%
-15.7%
Q3 25
7.5%
-45.1%
Q2 25
-36.3%
-43.4%
Q1 25
73.7%
-55.9%
Q4 24
-30.9%
-42.7%
Q3 24
-54.2%
-29.8%
Q2 24
-53.1%
-49.4%
Q1 24
-43.6%
-49.4%
EPS (diluted)
PTCT
PTCT
UP
UP
Q4 25
$-1.63
$-0.04
Q3 25
$0.20
$-0.12
Q2 25
$-0.83
$-0.12
Q1 25
$10.04
$-0.14
Q4 24
$-0.85
$-0.13
Q3 24
$-1.39
$-0.08
Q2 24
$-1.29
$-0.14
Q1 24
$-1.20
$-0.14

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
PTCT
PTCT
UP
UP
Cash + ST InvestmentsLiquidity on hand
$1.9B
$133.9M
Total DebtLower is stronger
$671.3M
Stockholders' EquityBook value
$-205.3M
$-392.1M
Total Assets
$2.9B
$968.8M
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
PTCT
PTCT
UP
UP
Q4 25
$1.9B
$133.9M
Q3 25
$1.7B
$125.3M
Q2 25
$2.0B
$107.0M
Q1 25
$2.0B
$171.8M
Q4 24
$1.1B
$216.4M
Q3 24
$1.0B
$115.9M
Q2 24
$1.1B
$141.5M
Q1 24
$884.8M
$180.9M
Total Debt
PTCT
PTCT
UP
UP
Q4 25
$671.3M
Q3 25
$766.5M
Q2 25
$770.5M
Q1 25
$765.8M
Q4 24
$761.3M
Q3 24
$596.9M
Q2 24
$597.4M
Q1 24
$603.2M
Stockholders' Equity
PTCT
PTCT
UP
UP
Q4 25
$-205.3M
$-392.1M
Q3 25
$-155.8M
$-374.5M
Q2 25
$-206.5M
$-347.8M
Q1 25
$-185.8M
$-288.1M
Q4 24
$-1.1B
$-202.1M
Q3 24
$-1.1B
$-117.7M
Q2 24
$-980.2M
$-72.2M
Q1 24
$-893.9M
$936.0K
Total Assets
PTCT
PTCT
UP
UP
Q4 25
$2.9B
$968.8M
Q3 25
$2.6B
$973.0M
Q2 25
$2.6B
$1.0B
Q1 25
$2.7B
$1.1B
Q4 24
$1.7B
$1.2B
Q3 24
$1.8B
$1.0B
Q2 24
$1.9B
$1.1B
Q1 24
$1.8B
$1.2B
Debt / Equity
PTCT
PTCT
UP
UP
Q4 25
Q3 25
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24
644.43×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
PTCT
PTCT
UP
UP
Operating Cash FlowLast quarter
$-34.3M
$-18.4M
Free Cash FlowOCF − Capex
$-36.6M
$-58.3M
FCF MarginFCF / Revenue
-22.3%
-31.7%
Capex IntensityCapex / Revenue
1.4%
21.7%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$702.3M
$-259.9M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
PTCT
PTCT
UP
UP
Q4 25
$-34.3M
$-18.4M
Q3 25
$-66.3M
$-37.1M
Q2 25
$-58.3M
$-62.9M
Q1 25
$870.1M
$-47.9M
Q4 24
$-30.0M
$37.9M
Q3 24
$-77.0M
$-16.9M
Q2 24
$-71.5M
$-25.2M
Q1 24
$70.8M
$-73.8M
Free Cash Flow
PTCT
PTCT
UP
UP
Q4 25
$-36.6M
$-58.3M
Q3 25
$-69.7M
$-60.4M
Q2 25
$-59.6M
$-78.6M
Q1 25
$868.4M
$-62.6M
Q4 24
$-33.8M
$-70.2M
Q3 24
$-77.5M
$-21.9M
Q2 24
$-78.8M
$-30.8M
Q1 24
$61.2M
$-77.8M
FCF Margin
PTCT
PTCT
UP
UP
Q4 25
-22.3%
-31.7%
Q3 25
-33.1%
-32.6%
Q2 25
-33.3%
-41.5%
Q1 25
73.8%
-35.3%
Q4 24
-15.8%
-34.3%
Q3 24
-39.4%
-11.3%
Q2 24
-42.2%
-15.7%
Q1 24
29.1%
-39.5%
Capex Intensity
PTCT
PTCT
UP
UP
Q4 25
1.4%
21.7%
Q3 25
1.6%
12.5%
Q2 25
0.7%
8.3%
Q1 25
0.1%
8.3%
Q4 24
1.8%
52.8%
Q3 24
0.3%
2.6%
Q2 24
4.0%
2.9%
Q1 24
4.6%
2.0%
Cash Conversion
PTCT
PTCT
UP
UP
Q4 25
Q3 25
-4.17×
Q2 25
Q1 25
1.00×
Q4 24
Q3 24
Q2 24
Q1 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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