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Side-by-side financial comparison of Protagonist Therapeutics, Inc (PTGX) and LiveRamp Holdings, Inc. (RAMP). Click either name above to swap in a different company.

LiveRamp Holdings, Inc. is the larger business by last-quarter revenue ($212.2M vs $170.6M, roughly 1.2× Protagonist Therapeutics, Inc). Protagonist Therapeutics, Inc runs the higher net margin — 77.2% vs 18.8%, a 58.4% gap on every dollar of revenue. On growth, Protagonist Therapeutics, Inc posted the faster year-over-year revenue change (184.4% vs 8.6%).

Protagonist Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on discovering and developing novel peptide-based targeted therapies for unmet medical needs, primarily covering gastrointestinal disorders, inflammatory diseases and rare disease indications. Its lead product candidates target inflammatory bowel disease and other chronic immune-related conditions, with operations spanning global R&D and partnership collaborations.

LiveRamp Holdings, Inc., is an American SaaS company that offers a data connectivity platform whose services include data onboarding, the transfer of offline data online for marketing purposes.

PTGX vs RAMP — Head-to-Head

Bigger by revenue
RAMP
RAMP
1.2× larger
RAMP
$212.2M
$170.6M
PTGX
Growing faster (revenue YoY)
PTGX
PTGX
+175.8% gap
PTGX
184.4%
8.6%
RAMP
Higher net margin
PTGX
PTGX
58.4% more per $
PTGX
77.2%
18.8%
RAMP

Income Statement — Q4 FY2024 vs Q3 FY2026

Metric
PTGX
PTGX
RAMP
RAMP
Revenue
$170.6M
$212.2M
Net Profit
$131.7M
$39.9M
Gross Margin
71.9%
Operating Margin
74.3%
18.6%
Net Margin
77.2%
18.8%
Revenue YoY
184.4%
8.6%
Net Profit YoY
381.7%
255.7%
EPS (diluted)
$2.01
$0.62

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
PTGX
PTGX
RAMP
RAMP
Q4 25
$212.2M
Q3 25
$199.8M
Q2 25
$194.8M
Q1 25
$188.7M
Q4 24
$170.6M
$195.4M
Q3 24
$185.5M
Q2 24
$176.0M
Q1 24
$255.0M
$171.9M
Net Profit
PTGX
PTGX
RAMP
RAMP
Q4 25
$39.9M
Q3 25
$27.4M
Q2 25
$7.7M
Q1 25
$-6.3M
Q4 24
$131.7M
$11.2M
Q3 24
$1.7M
Q2 24
$-7.5M
Q1 24
$207.3M
$-5.4M
Gross Margin
PTGX
PTGX
RAMP
RAMP
Q4 25
71.9%
Q3 25
70.2%
Q2 25
70.1%
Q1 25
69.3%
Q4 24
71.9%
Q3 24
72.4%
Q2 24
70.6%
Q1 24
72.2%
Operating Margin
PTGX
PTGX
RAMP
RAMP
Q4 25
18.6%
Q3 25
10.7%
Q2 25
3.7%
Q1 25
-6.1%
Q4 24
74.3%
7.5%
Q3 24
4.0%
Q2 24
-3.0%
Q1 24
80.9%
-8.3%
Net Margin
PTGX
PTGX
RAMP
RAMP
Q4 25
18.8%
Q3 25
13.7%
Q2 25
4.0%
Q1 25
-3.3%
Q4 24
77.2%
5.7%
Q3 24
0.9%
Q2 24
-4.3%
Q1 24
81.3%
-3.1%
EPS (diluted)
PTGX
PTGX
RAMP
RAMP
Q4 25
$0.62
Q3 25
$0.42
Q2 25
$0.12
Q1 25
$-0.10
Q4 24
$2.01
$0.17
Q3 24
$0.03
Q2 24
$-0.11
Q1 24
$3.26
$-0.09

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
PTGX
PTGX
RAMP
RAMP
Cash + ST InvestmentsLiquidity on hand
$418.9M
$403.4M
Total DebtLower is stronger
Stockholders' EquityBook value
$675.3M
$962.3M
Total Assets
$744.7M
$1.3B
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
PTGX
PTGX
RAMP
RAMP
Q4 25
$403.4M
Q3 25
$376.9M
Q2 25
$371.1M
Q1 25
$420.8M
Q4 24
$418.9M
$384.3M
Q3 24
$348.4M
Q2 24
$342.7M
Q1 24
$322.6M
$368.9M
Stockholders' Equity
PTGX
PTGX
RAMP
RAMP
Q4 25
$962.3M
Q3 25
$943.8M
Q2 25
$947.8M
Q1 25
$948.9M
Q4 24
$675.3M
$957.7M
Q3 24
$932.1M
Q2 24
$951.9M
Q1 24
$560.4M
$949.1M
Total Assets
PTGX
PTGX
RAMP
RAMP
Q4 25
$1.3B
Q3 25
$1.2B
Q2 25
$1.2B
Q1 25
$1.3B
Q4 24
$744.7M
$1.3B
Q3 24
$1.2B
Q2 24
$1.2B
Q1 24
$629.3M
$1.2B

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
PTGX
PTGX
RAMP
RAMP
Operating Cash FlowLast quarter
$184.2M
Free Cash FlowOCF − Capex
$182.8M
FCF MarginFCF / Revenue
107.1%
Capex IntensityCapex / Revenue
0.8%
0.1%
Cash ConversionOCF / Net Profit
1.40×
TTM Free Cash FlowTrailing 4 quarters
$101.7M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
PTGX
PTGX
RAMP
RAMP
Q4 25
Q3 25
$57.4M
Q2 25
$-15.8M
Q1 25
Q4 24
$184.2M
$45.1M
Q3 24
$55.6M
Q2 24
$-9.3M
Q1 24
$-27.4M
Free Cash Flow
PTGX
PTGX
RAMP
RAMP
Q4 25
Q3 25
$56.8M
Q2 25
$-16.2M
Q1 25
Q4 24
$182.8M
$44.8M
Q3 24
$55.4M
Q2 24
$-9.6M
Q1 24
$-27.7M
FCF Margin
PTGX
PTGX
RAMP
RAMP
Q4 25
Q3 25
28.4%
Q2 25
-8.3%
Q1 25
Q4 24
107.1%
22.9%
Q3 24
29.8%
Q2 24
-5.4%
Q1 24
-10.9%
Capex Intensity
PTGX
PTGX
RAMP
RAMP
Q4 25
0.1%
Q3 25
0.3%
Q2 25
0.2%
Q1 25
0.2%
Q4 24
0.8%
0.1%
Q3 24
0.1%
Q2 24
0.1%
Q1 24
0.1%
1.0%
Cash Conversion
PTGX
PTGX
RAMP
RAMP
Q4 25
Q3 25
2.09×
Q2 25
-2.04×
Q1 25
Q4 24
1.40×
4.02×
Q3 24
32.10×
Q2 24
Q1 24
-0.13×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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