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Side-by-side financial comparison of Protagonist Therapeutics, Inc (PTGX) and Resolute Holdings Management, Inc. (RHLD). Click either name above to swap in a different company.

Protagonist Therapeutics, Inc is the larger business by last-quarter revenue ($170.6M vs $117.7M, roughly 1.4× Resolute Holdings Management, Inc.). Protagonist Therapeutics, Inc runs the higher net margin — 77.2% vs -1.5%, a 78.6% gap on every dollar of revenue. Resolute Holdings Management, Inc. produced more free cash flow last quarter ($189.2M vs $182.8M).

Protagonist Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on discovering and developing novel peptide-based targeted therapies for unmet medical needs, primarily covering gastrointestinal disorders, inflammatory diseases and rare disease indications. Its lead product candidates target inflammatory bowel disease and other chronic immune-related conditions, with operations spanning global R&D and partnership collaborations.

Resolute Mining Limited is an Australian mining corporation focused on mining operations in Africa. It is currently operating two gold mines: the Syama Gold Mine in Mali and the Mako Gold Mine in Senegal.

PTGX vs RHLD — Head-to-Head

Bigger by revenue
PTGX
PTGX
1.4× larger
PTGX
$170.6M
$117.7M
RHLD
Higher net margin
PTGX
PTGX
78.6% more per $
PTGX
77.2%
-1.5%
RHLD
More free cash flow
RHLD
RHLD
$6.4M more FCF
RHLD
$189.2M
$182.8M
PTGX

Income Statement — Q4 FY2024 vs Q4 FY2025

Metric
PTGX
PTGX
RHLD
RHLD
Revenue
$170.6M
$117.7M
Net Profit
$131.7M
$-1.7M
Gross Margin
55.7%
Operating Margin
74.3%
30.2%
Net Margin
77.2%
-1.5%
Revenue YoY
184.4%
Net Profit YoY
381.7%
EPS (diluted)
$2.01
$-0.20

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
PTGX
PTGX
RHLD
RHLD
Q4 25
$117.7M
Q3 25
$120.9M
Q2 25
$119.6M
Q1 25
$103.9M
Q4 24
$170.6M
Q1 24
$255.0M
Q3 23
$0
Q2 23
$0
Net Profit
PTGX
PTGX
RHLD
RHLD
Q4 25
$-1.7M
Q3 25
$-231.0K
Q2 25
$-611.0K
Q1 25
$-3.4M
Q4 24
$131.7M
Q1 24
$207.3M
Q3 23
$-34.1M
Q2 23
$-38.5M
Gross Margin
PTGX
PTGX
RHLD
RHLD
Q4 25
55.7%
Q3 25
59.0%
Q2 25
57.5%
Q1 25
52.5%
Q4 24
Q1 24
Q3 23
Q2 23
Operating Margin
PTGX
PTGX
RHLD
RHLD
Q4 25
30.2%
Q3 25
34.3%
Q2 25
34.0%
Q1 25
24.7%
Q4 24
74.3%
Q1 24
80.9%
Q3 23
Q2 23
Net Margin
PTGX
PTGX
RHLD
RHLD
Q4 25
-1.5%
Q3 25
-0.2%
Q2 25
-0.5%
Q1 25
-3.2%
Q4 24
77.2%
Q1 24
81.3%
Q3 23
Q2 23
EPS (diluted)
PTGX
PTGX
RHLD
RHLD
Q4 25
$-0.20
Q3 25
$-0.03
Q2 25
$-0.07
Q1 25
$-0.39
Q4 24
$2.01
Q1 24
$3.26
Q3 23
$-0.58
Q2 23
$-0.68

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
PTGX
PTGX
RHLD
RHLD
Cash + ST InvestmentsLiquidity on hand
$418.9M
$205.5M
Total DebtLower is stronger
$169.8M
Stockholders' EquityBook value
$675.3M
$6.5M
Total Assets
$744.7M
$333.4M
Debt / EquityLower = less leverage
26.03×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
PTGX
PTGX
RHLD
RHLD
Q4 25
$205.5M
Q3 25
$148.0M
Q2 25
$99.9M
Q1 25
$71.0M
Q4 24
$418.9M
Q1 24
$322.6M
Q3 23
$320.8M
Q2 23
$313.4M
Total Debt
PTGX
PTGX
RHLD
RHLD
Q4 25
$169.8M
Q3 25
$173.4M
Q2 25
$177.1M
Q1 25
$180.7M
Q4 24
Q1 24
Q3 23
Q2 23
Stockholders' Equity
PTGX
PTGX
RHLD
RHLD
Q4 25
$6.5M
Q3 25
$10.8M
Q2 25
$9.6M
Q1 25
$8.9M
Q4 24
$675.3M
Q1 24
$560.4M
Q3 23
$302.1M
Q2 23
$294.1M
Total Assets
PTGX
PTGX
RHLD
RHLD
Q4 25
$333.4M
Q3 25
$293.2M
Q2 25
$253.3M
Q1 25
$214.3M
Q4 24
$744.7M
Q1 24
$629.3M
Q3 23
$330.0M
Q2 23
$320.5M
Debt / Equity
PTGX
PTGX
RHLD
RHLD
Q4 25
26.03×
Q3 25
16.01×
Q2 25
18.42×
Q1 25
20.38×
Q4 24
Q1 24
Q3 23
Q2 23

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
PTGX
PTGX
RHLD
RHLD
Operating Cash FlowLast quarter
$184.2M
$196.1M
Free Cash FlowOCF − Capex
$182.8M
$189.2M
FCF MarginFCF / Revenue
107.1%
160.8%
Capex IntensityCapex / Revenue
0.8%
5.8%
Cash ConversionOCF / Net Profit
1.40×
TTM Free Cash FlowTrailing 4 quarters
$101.7M
$313.2M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
PTGX
PTGX
RHLD
RHLD
Q4 25
$196.1M
Q3 25
$59.6M
Q2 25
$48.9M
Q1 25
$18.4M
Q4 24
$184.2M
Q1 24
$-27.4M
Q3 23
$-26.6M
Q2 23
$-26.2M
Free Cash Flow
PTGX
PTGX
RHLD
RHLD
Q4 25
$189.2M
Q3 25
$58.6M
Q2 25
$47.5M
Q1 25
$17.8M
Q4 24
$182.8M
Q1 24
$-27.7M
Q3 23
$-27.0M
Q2 23
$-26.4M
FCF Margin
PTGX
PTGX
RHLD
RHLD
Q4 25
160.8%
Q3 25
48.5%
Q2 25
39.7%
Q1 25
17.1%
Q4 24
107.1%
Q1 24
-10.9%
Q3 23
Q2 23
Capex Intensity
PTGX
PTGX
RHLD
RHLD
Q4 25
5.8%
Q3 25
0.8%
Q2 25
1.2%
Q1 25
0.6%
Q4 24
0.8%
Q1 24
0.1%
Q3 23
Q2 23
Cash Conversion
PTGX
PTGX
RHLD
RHLD
Q4 25
Q3 25
Q2 25
Q1 25
Q4 24
1.40×
Q1 24
-0.13×
Q3 23
Q2 23

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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