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Side-by-side financial comparison of Protagonist Therapeutics, Inc (PTGX) and Thryv Holdings, Inc. (THRY). Click either name above to swap in a different company.

Protagonist Therapeutics, Inc is the larger business by last-quarter revenue ($170.6M vs $167.7M, roughly 1.0× Thryv Holdings, Inc.). Protagonist Therapeutics, Inc runs the higher net margin — 77.2% vs 2.7%, a 74.5% gap on every dollar of revenue. On growth, Protagonist Therapeutics, Inc posted the faster year-over-year revenue change (184.4% vs -7.5%). Protagonist Therapeutics, Inc produced more free cash flow last quarter ($182.8M vs $-5.5M).

Protagonist Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on discovering and developing novel peptide-based targeted therapies for unmet medical needs, primarily covering gastrointestinal disorders, inflammatory diseases and rare disease indications. Its lead product candidates target inflammatory bowel disease and other chronic immune-related conditions, with operations spanning global R&D and partnership collaborations.

Thryv Holdings, Inc. is a publicly traded software as a service (SaaS) company, providing customer relationship management and online reputation management software for small businesses. It has headquarters in Dallas, Texas, and operates in 48 states across the United States of America with more than 2,400 employees. The company began as a conglomerate of Yellow Pages companies. In June 2020, Thryv reported $1.3 billion in revenue over a twelve-month period.

PTGX vs THRY — Head-to-Head

Bigger by revenue
PTGX
PTGX
1.0× larger
PTGX
$170.6M
$167.7M
THRY
Growing faster (revenue YoY)
PTGX
PTGX
+191.9% gap
PTGX
184.4%
-7.5%
THRY
Higher net margin
PTGX
PTGX
74.5% more per $
PTGX
77.2%
2.7%
THRY
More free cash flow
PTGX
PTGX
$188.3M more FCF
PTGX
$182.8M
$-5.5M
THRY

Income Statement — Q4 FY2024 vs Q1 FY2026

Metric
PTGX
PTGX
THRY
THRY
Revenue
$170.6M
$167.7M
Net Profit
$131.7M
$4.5M
Gross Margin
65.2%
Operating Margin
74.3%
37.3%
Net Margin
77.2%
2.7%
Revenue YoY
184.4%
-7.5%
Net Profit YoY
381.7%
147.2%
EPS (diluted)
$2.01
$0.10

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
PTGX
PTGX
THRY
THRY
Q1 26
$167.7M
Q4 25
$191.6M
Q3 25
$201.6M
Q2 25
$210.5M
Q1 25
$181.4M
Q4 24
$170.6M
$186.6M
Q3 24
$179.9M
Q2 24
$224.1M
Net Profit
PTGX
PTGX
THRY
THRY
Q1 26
$4.5M
Q4 25
$-9.7M
Q3 25
$5.7M
Q2 25
$13.9M
Q1 25
$-9.6M
Q4 24
$131.7M
$7.9M
Q3 24
$-96.1M
Q2 24
$5.5M
Gross Margin
PTGX
PTGX
THRY
THRY
Q1 26
65.2%
Q4 25
68.0%
Q3 25
67.7%
Q2 25
69.7%
Q1 25
65.8%
Q4 24
65.9%
Q3 24
62.3%
Q2 24
66.3%
Operating Margin
PTGX
PTGX
THRY
THRY
Q1 26
37.3%
Q4 25
5.3%
Q3 25
9.9%
Q2 25
14.0%
Q1 25
-1.7%
Q4 24
74.3%
-3.9%
Q3 24
-49.2%
Q2 24
14.0%
Net Margin
PTGX
PTGX
THRY
THRY
Q1 26
2.7%
Q4 25
-5.0%
Q3 25
2.8%
Q2 25
6.6%
Q1 25
-5.3%
Q4 24
77.2%
4.2%
Q3 24
-53.4%
Q2 24
2.5%
EPS (diluted)
PTGX
PTGX
THRY
THRY
Q1 26
$0.10
Q4 25
$-0.21
Q3 25
$0.13
Q2 25
$0.31
Q1 25
$-0.22
Q4 24
$2.01
$0.28
Q3 24
$-2.65
Q2 24
$0.15

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
PTGX
PTGX
THRY
THRY
Cash + ST InvestmentsLiquidity on hand
$418.9M
$8.0M
Total DebtLower is stronger
Stockholders' EquityBook value
$675.3M
$225.4M
Total Assets
$744.7M
$693.7M
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
PTGX
PTGX
THRY
THRY
Q1 26
$8.0M
Q4 25
$10.8M
Q3 25
$11.6M
Q2 25
$10.8M
Q1 25
$11.0M
Q4 24
$418.9M
$16.3M
Q3 24
$12.5M
Q2 24
$15.5M
Total Debt
PTGX
PTGX
THRY
THRY
Q1 26
Q4 25
$253.5M
Q3 25
$268.2M
Q2 25
$275.6M
Q1 25
$299.0M
Q4 24
$284.3M
Q3 24
$307.8M
Q2 24
$342.1M
Stockholders' Equity
PTGX
PTGX
THRY
THRY
Q1 26
$225.4M
Q4 25
$218.1M
Q3 25
$221.1M
Q2 25
$214.9M
Q1 25
$193.2M
Q4 24
$675.3M
$196.9M
Q3 24
$94.5M
Q2 24
$183.1M
Total Assets
PTGX
PTGX
THRY
THRY
Q1 26
$693.7M
Q4 25
$688.6M
Q3 25
$701.8M
Q2 25
$687.7M
Q1 25
$703.7M
Q4 24
$744.7M
$712.2M
Q3 24
$654.8M
Q2 24
$785.5M
Debt / Equity
PTGX
PTGX
THRY
THRY
Q1 26
Q4 25
1.16×
Q3 25
1.21×
Q2 25
1.28×
Q1 25
1.55×
Q4 24
1.44×
Q3 24
3.26×
Q2 24
1.87×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
PTGX
PTGX
THRY
THRY
Operating Cash FlowLast quarter
$184.2M
Free Cash FlowOCF − Capex
$182.8M
$-5.5M
FCF MarginFCF / Revenue
107.1%
-3.3%
Capex IntensityCapex / Revenue
0.8%
Cash ConversionOCF / Net Profit
1.40×
TTM Free Cash FlowTrailing 4 quarters
$101.7M
$43.3M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
PTGX
PTGX
THRY
THRY
Q1 26
Q4 25
$22.2M
Q3 25
$22.2M
Q2 25
$29.6M
Q1 25
$-10.5M
Q4 24
$184.2M
$26.1M
Q3 24
$36.0M
Q2 24
$22.2M
Free Cash Flow
PTGX
PTGX
THRY
THRY
Q1 26
$-5.5M
Q4 25
$12.3M
Q3 25
$14.6M
Q2 25
$21.8M
Q1 25
$-17.6M
Q4 24
$182.8M
$17.3M
Q3 24
$27.5M
Q2 24
$13.3M
FCF Margin
PTGX
PTGX
THRY
THRY
Q1 26
-3.3%
Q4 25
6.4%
Q3 25
7.2%
Q2 25
10.4%
Q1 25
-9.7%
Q4 24
107.1%
9.3%
Q3 24
15.3%
Q2 24
5.9%
Capex Intensity
PTGX
PTGX
THRY
THRY
Q1 26
Q4 25
5.2%
Q3 25
3.8%
Q2 25
3.7%
Q1 25
3.9%
Q4 24
0.8%
4.7%
Q3 24
4.7%
Q2 24
4.0%
Cash Conversion
PTGX
PTGX
THRY
THRY
Q1 26
Q4 25
Q3 25
3.93×
Q2 25
2.12×
Q1 25
Q4 24
1.40×
3.32×
Q3 24
Q2 24
4.01×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

PTGX
PTGX

Segment breakdown not available.

THRY
THRY

SaaS$116.7M70%
Other$50.9M30%

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