vs

Side-by-side financial comparison of Pelthos Therapeutics Inc. (PTHS) and SmartKem, Inc. (SMTK). Click either name above to swap in a different company.

SmartKem, Inc. is the larger business by last-quarter revenue ($561.0K vs $294.0K, roughly 1.9× Pelthos Therapeutics Inc.). SmartKem, Inc. runs the higher net margin — -366.3% vs -5523.1%, a 5156.8% gap on every dollar of revenue.

Pelthos Therapeutics Inc. is a clinical-stage biopharmaceutical company focused on discovering, developing, and commercializing targeted therapies for rare metabolic and endocrine diseases with significant unmet medical needs. It operates primarily across North America and Europe, with a pipeline of novel drug candidates addressing underserved patient populations.

SmartKem, Inc. is an advanced materials developer focused on proprietary organic semiconductor formulations designed for flexible and foldable display panels, printed electronics, and next-generation optoelectronic devices. It serves global consumer electronics display manufacturers and semiconductor component producers across North America, East Asia and Europe.

PTHS vs SMTK — Head-to-Head

Bigger by revenue
SMTK
SMTK
1.9× larger
SMTK
$561.0K
$294.0K
PTHS
Higher net margin
SMTK
SMTK
5156.8% more per $
SMTK
-366.3%
-5523.1%
PTHS

Income Statement — Q3 FY2025 vs Q4 FY2025

Metric
PTHS
PTHS
SMTK
SMTK
Revenue
$294.0K
$561.0K
Net Profit
$-16.2M
$-2.1M
Gross Margin
-687.8%
57.6%
Operating Margin
-5225.2%
-380.7%
Net Margin
-5523.1%
-366.3%
Revenue YoY
Net Profit YoY
-858.0%
23.7%
EPS (diluted)
$-5.30
$-0.22

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
PTHS
PTHS
SMTK
SMTK
Q4 25
$561.0K
Q3 25
$294.0K
$81.0K
Q3 24
$0
Q4 23
$0
Q3 23
$3.0K
Q2 23
$8.0K
Q1 23
$16.0K
Q4 22
$-20.0K
Net Profit
PTHS
PTHS
SMTK
SMTK
Q4 25
$-2.1M
Q3 25
$-16.2M
$-3.9M
Q3 24
$-2.8M
Q4 23
$-1.4M
Q3 23
$-3.0M
Q2 23
$-2.0M
Q1 23
$-2.0M
Q4 22
$-1.1M
Gross Margin
PTHS
PTHS
SMTK
SMTK
Q4 25
57.6%
Q3 25
-687.8%
93.8%
Q3 24
Q4 23
Q3 23
66.7%
Q2 23
25.0%
Q1 23
Q4 22
Operating Margin
PTHS
PTHS
SMTK
SMTK
Q4 25
-380.7%
Q3 25
-5225.2%
-3937.0%
Q3 24
Q4 23
Q3 23
-89833.3%
Q2 23
-29587.5%
Q1 23
-15962.5%
Q4 22
12035.0%
Net Margin
PTHS
PTHS
SMTK
SMTK
Q4 25
-366.3%
Q3 25
-5523.1%
-4839.5%
Q3 24
Q4 23
Q3 23
-100733.3%
Q2 23
-25337.5%
Q1 23
-12800.0%
Q4 22
5395.0%
EPS (diluted)
PTHS
PTHS
SMTK
SMTK
Q4 25
$-0.22
Q3 25
$-5.30
$-0.45
Q3 24
$-0.86
Q4 23
$-0.27
Q3 23
$-1.78
Q2 23
$-1.82
Q1 23
$-2.45
Q4 22
$-8.90

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
PTHS
PTHS
SMTK
SMTK
Cash + ST InvestmentsLiquidity on hand
$14.2M
$374.0K
Total DebtLower is stronger
Stockholders' EquityBook value
$58.3M
$-3.9M
Total Assets
$126.4M
$2.3M
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
PTHS
PTHS
SMTK
SMTK
Q4 25
$374.0K
Q3 25
$14.2M
$881.0K
Q3 24
$1.8M
Q4 23
$8.8M
Q3 23
$11.2M
Q2 23
$13.8M
Q1 23
$1.7M
Q4 22
$4.2M
Stockholders' Equity
PTHS
PTHS
SMTK
SMTK
Q4 25
$-3.9M
Q3 25
$58.3M
$-3.0M
Q3 24
$2.3M
Q4 23
$8.1M
Q3 23
$10.3M
Q2 23
$12.3M
Q1 23
$3.7M
Q4 22
$5.9M
Total Assets
PTHS
PTHS
SMTK
SMTK
Q4 25
$2.3M
Q3 25
$126.4M
$3.2M
Q3 24
$4.3M
Q4 23
$11.3M
Q3 23
$13.6M
Q2 23
$16.1M
Q1 23
$5.3M
Q4 22
$7.5M

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
PTHS
PTHS
SMTK
SMTK
Operating Cash FlowLast quarter
$-15.3M
$-1.4M
Free Cash FlowOCF − Capex
FCF MarginFCF / Revenue
Capex IntensityCapex / Revenue
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
PTHS
PTHS
SMTK
SMTK
Q4 25
$-1.4M
Q3 25
$-15.3M
$-200.0K
Q3 24
$-2.6M
Q4 23
$-2.4M
Q3 23
$-2.5M
Q2 23
$-637.0K
Q1 23
$-2.4M
Q4 22
$-2.2M
Free Cash Flow
PTHS
PTHS
SMTK
SMTK
Q4 25
Q3 25
Q3 24
Q4 23
Q3 23
$-2.6M
Q2 23
Q1 23
Q4 22
$-2.2M
FCF Margin
PTHS
PTHS
SMTK
SMTK
Q4 25
Q3 25
Q3 24
Q4 23
Q3 23
-85200.0%
Q2 23
Q1 23
Q4 22
11130.0%
Capex Intensity
PTHS
PTHS
SMTK
SMTK
Q4 25
Q3 25
Q3 24
Q4 23
Q3 23
200.0%
Q2 23
Q1 23
Q4 22
-60.0%

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Related Comparisons