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Side-by-side financial comparison of Relay Therapeutics, Inc. (RLAY) and SMITH MICRO SOFTWARE, INC. (SMSI). Click either name above to swap in a different company.

Relay Therapeutics, Inc. is the larger business by last-quarter revenue ($7.0M vs $4.0M, roughly 1.8× SMITH MICRO SOFTWARE, INC.).

Relay Therapeutics is a clinical-stage biotechnology company focused on developing precision oncology therapies. It leverages advanced computational modeling of protein dynamics, paired with cutting-edge experimental biology, to design targeted medicines for previously intractable cancer types, serving global oncology care markets and patient populations.

Smith Micro Software, Inc., founded in 1982 by William W. Smith, Jr., is a developer and marketer of both enterprise and consumer-level software and services. Headquartered in Pittsburgh, Pennsylvania, Smith Micro maintains multiple domestic and international offices. United States locations include Aliso Viejo, California, and Pittsburgh, Pennsylvania. International offices are located throughout Europe and Asia. Currently, the company focuses on digital lifestyle solutions and security tech...

RLAY vs SMSI — Head-to-Head

Bigger by revenue
RLAY
RLAY
1.8× larger
RLAY
$7.0M
$4.0M
SMSI

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
RLAY
RLAY
SMSI
SMSI
Revenue
$7.0M
$4.0M
Net Profit
Gross Margin
76.4%
Operating Margin
-109.8%
Net Margin
Revenue YoY
-20.0%
Net Profit YoY
EPS (diluted)
$-0.15

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
RLAY
RLAY
SMSI
SMSI
Q4 25
$7.0M
$4.0M
Q3 25
$0
$4.3M
Q2 25
$4.4M
Q1 25
$7.7M
$4.6M
Q4 24
$0
$5.0M
Q3 24
$0
$4.6M
Q2 24
$0
$5.1M
Q1 24
$10.0M
$5.8M
Net Profit
RLAY
RLAY
SMSI
SMSI
Q4 25
Q3 25
$-74.1M
$-4.5M
Q2 25
$-15.1M
Q1 25
$-77.1M
$-5.2M
Q4 24
Q3 24
$-88.1M
$-6.4M
Q2 24
$-92.2M
$-6.9M
Q1 24
$-81.4M
$-31.0M
Gross Margin
RLAY
RLAY
SMSI
SMSI
Q4 25
76.4%
Q3 25
73.9%
Q2 25
73.5%
Q1 25
72.8%
Q4 24
75.6%
Q3 24
71.6%
Q2 24
68.7%
Q1 24
65.7%
Operating Margin
RLAY
RLAY
SMSI
SMSI
Q4 25
-109.8%
Q3 25
-103.2%
Q2 25
-338.3%
Q1 25
-1105.2%
-112.7%
Q4 24
-89.7%
Q3 24
-140.0%
Q2 24
-135.8%
Q1 24
-903.0%
-542.4%
Net Margin
RLAY
RLAY
SMSI
SMSI
Q4 25
Q3 25
-104.3%
Q2 25
-340.8%
Q1 25
-1003.6%
-112.1%
Q4 24
Q3 24
-137.0%
Q2 24
-134.8%
Q1 24
-813.3%
-534.8%
EPS (diluted)
RLAY
RLAY
SMSI
SMSI
Q4 25
$-0.15
Q3 25
$-0.43
$-0.25
Q2 25
$-0.78
Q1 25
$-0.46
$-0.28
Q4 24
$0.54
Q3 24
$-0.63
$-0.54
Q2 24
$-0.69
$-0.66
Q1 24
$-0.62
$-3.28

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
RLAY
RLAY
SMSI
SMSI
Cash + ST InvestmentsLiquidity on hand
$84.0M
$1.5M
Total DebtLower is stronger
Stockholders' EquityBook value
$567.1M
$18.4M
Total Assets
$621.3M
$25.0M
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
RLAY
RLAY
SMSI
SMSI
Q4 25
$84.0M
$1.5M
Q3 25
$91.6M
$1.4M
Q2 25
$1.4M
Q1 25
$93.5M
$2.3M
Q4 24
$124.3M
$2.8M
Q3 24
$152.4M
$1.5M
Q2 24
$134.1M
$5.6M
Q1 24
$152.9M
$6.2M
Stockholders' Equity
RLAY
RLAY
SMSI
SMSI
Q4 25
$567.1M
$18.4M
Q3 25
$607.7M
$19.9M
Q2 25
$22.4M
Q1 25
$721.1M
$36.6M
Q4 24
$777.8M
$40.8M
Q3 24
$838.9M
$37.7M
Q2 24
$681.7M
$42.9M
Q1 24
$745.8M
$45.4M
Total Assets
RLAY
RLAY
SMSI
SMSI
Q4 25
$621.3M
$25.0M
Q3 25
$670.0M
$27.1M
Q2 25
$29.6M
Q1 25
$799.4M
$43.4M
Q4 24
$871.3M
$48.0M
Q3 24
$930.1M
$46.2M
Q2 24
$772.5M
$53.0M
Q1 24
$841.4M
$55.4M

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
RLAY
RLAY
SMSI
SMSI
Operating Cash FlowLast quarter
$-235.5M
$-2.2M
Free Cash FlowOCF − Capex
$-235.9M
FCF MarginFCF / Revenue
-3370.0%
Capex IntensityCapex / Revenue
5.9%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$-622.7M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
RLAY
RLAY
SMSI
SMSI
Q4 25
$-235.5M
$-2.2M
Q3 25
$-62.1M
$-2.1M
Q2 25
$-2.3M
Q1 25
$-73.2M
$-602.0K
Q4 24
$-249.1M
$-4.9M
Q3 24
$-75.1M
$-3.8M
Q2 24
$-65.8M
$-4.2M
Q1 24
$-50.3M
$-1.3M
Free Cash Flow
RLAY
RLAY
SMSI
SMSI
Q4 25
$-235.9M
Q3 25
$-62.1M
$-2.2M
Q2 25
Q1 25
$-73.6M
$-606.0K
Q4 24
$-251.1M
$-4.9M
Q3 24
$-75.3M
$-3.8M
Q2 24
$-65.8M
$-4.2M
Q1 24
$-52.1M
$-1.3M
FCF Margin
RLAY
RLAY
SMSI
SMSI
Q4 25
-3370.0%
Q3 25
-49.6%
Q2 25
Q1 25
-958.4%
-13.1%
Q4 24
-99.2%
Q3 24
-82.2%
Q2 24
-82.0%
Q1 24
-520.7%
-23.3%
Capex Intensity
RLAY
RLAY
SMSI
SMSI
Q4 25
5.9%
Q3 25
0.5%
Q2 25
Q1 25
5.0%
0.1%
Q4 24
0.1%
Q3 24
0.1%
Q2 24
0.1%
Q1 24
17.8%
0.1%

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

RLAY
RLAY

Segment breakdown not available.

SMSI
SMSI

Family Safety$3.2M80%
Other$797.0K20%

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