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Side-by-side financial comparison of RHYTHM PHARMACEUTICALS, INC. (RYTM) and SANDRIDGE ENERGY INC (SD). Click either name above to swap in a different company.

RHYTHM PHARMACEUTICALS, INC. is the larger business by last-quarter revenue ($57.3M vs $39.4M, roughly 1.5× SANDRIDGE ENERGY INC). SANDRIDGE ENERGY INC runs the higher net margin — 54.9% vs -83.0%, a 137.9% gap on every dollar of revenue. On growth, RHYTHM PHARMACEUTICALS, INC. posted the faster year-over-year revenue change (36.9% vs 1.1%). Over the past eight quarters, RHYTHM PHARMACEUTICALS, INC.'s revenue compounded faster (48.5% CAGR vs 14.1%).

Rhythm Pharmaceuticals is a biopharmaceutical firm focused on developing and commercializing targeted therapies for rare genetic disorders causing severe unmanageable obesity, including POMC deficiency, LEPR deficiency, and Bardet-Biedl syndrome. It serves patients in North America and Europe who lack effective standard treatments for their chronic life-altering conditions.

SandRidge Energy, Inc. is a company engaged in hydrocarbon exploration in the Mid-Continent region of the United States. It is organized in Delaware and headquartered in Oklahoma City, Oklahoma.

RYTM vs SD — Head-to-Head

Bigger by revenue
RYTM
RYTM
1.5× larger
RYTM
$57.3M
$39.4M
SD
Growing faster (revenue YoY)
RYTM
RYTM
+35.8% gap
RYTM
36.9%
1.1%
SD
Higher net margin
SD
SD
137.9% more per $
SD
54.9%
-83.0%
RYTM
Faster 2-yr revenue CAGR
RYTM
RYTM
Annualised
RYTM
48.5%
14.1%
SD

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
RYTM
RYTM
SD
SD
Revenue
$57.3M
$39.4M
Net Profit
$-47.5M
$21.6M
Gross Margin
91.6%
Operating Margin
-82.2%
38.5%
Net Margin
-83.0%
54.9%
Revenue YoY
36.9%
1.1%
Net Profit YoY
-9.6%
23.1%
EPS (diluted)
$-0.73
$0.59

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
RYTM
RYTM
SD
SD
Q4 25
$57.3M
$39.4M
Q3 25
$51.3M
$39.8M
Q2 25
$48.5M
$34.5M
Q1 25
$32.7M
$42.6M
Q4 24
$41.8M
$39.0M
Q3 24
$33.3M
$30.1M
Q2 24
$29.1M
$26.0M
Q1 24
$26.0M
$30.3M
Net Profit
RYTM
RYTM
SD
SD
Q4 25
$-47.5M
$21.6M
Q3 25
$-52.9M
$16.0M
Q2 25
$-46.6M
$19.6M
Q1 25
$-49.5M
$13.0M
Q4 24
$-43.3M
$17.6M
Q3 24
$-43.6M
$25.5M
Q2 24
$-32.3M
$8.8M
Q1 24
$-141.4M
$11.1M
Gross Margin
RYTM
RYTM
SD
SD
Q4 25
91.6%
Q3 25
89.3%
Q2 25
88.6%
Q1 25
88.8%
Q4 24
90.9%
Q3 24
88.5%
Q2 24
89.9%
Q1 24
89.2%
Operating Margin
RYTM
RYTM
SD
SD
Q4 25
-82.2%
38.5%
Q3 25
-102.6%
37.8%
Q2 25
-93.4%
53.7%
Q1 25
-143.7%
28.6%
Q4 24
-98.6%
25.9%
Q3 24
-132.0%
28.3%
Q2 24
-139.2%
23.9%
Q1 24
-538.7%
27.8%
Net Margin
RYTM
RYTM
SD
SD
Q4 25
-83.0%
54.9%
Q3 25
-103.1%
40.1%
Q2 25
-96.1%
56.6%
Q1 25
-151.4%
30.6%
Q4 24
-103.6%
45.1%
Q3 24
-131.2%
84.8%
Q2 24
-110.9%
33.9%
Q1 24
-544.4%
36.7%
EPS (diluted)
RYTM
RYTM
SD
SD
Q4 25
$-0.73
$0.59
Q3 25
$-0.82
$0.43
Q2 25
$-0.75
$0.53
Q1 25
$-0.81
$0.35
Q4 24
$-0.71
$0.46
Q3 24
$-0.73
$0.69
Q2 24
$-0.55
$0.24
Q1 24
$-2.35
$0.30

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
RYTM
RYTM
SD
SD
Cash + ST InvestmentsLiquidity on hand
$388.9M
$111.0M
Total DebtLower is stronger
Stockholders' EquityBook value
$139.1M
$510.9M
Total Assets
$480.2M
$644.0M
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
RYTM
RYTM
SD
SD
Q4 25
$388.9M
$111.0M
Q3 25
$416.1M
$101.2M
Q2 25
$291.0M
$102.8M
Q1 25
$314.5M
$99.7M
Q4 24
$320.6M
$98.1M
Q3 24
$298.4M
$92.7M
Q2 24
$319.1M
$209.9M
Q1 24
$201.2M
$207.0M
Stockholders' Equity
RYTM
RYTM
SD
SD
Q4 25
$139.1M
$510.9M
Q3 25
$148.8M
$492.4M
Q2 25
$-11.9M
$480.2M
Q1 25
$18.9M
$464.9M
Q4 24
$21.7M
$460.5M
Q3 24
$11.2M
$446.8M
Q2 24
$39.3M
$424.8M
Q1 24
$61.6M
$419.7M
Total Assets
RYTM
RYTM
SD
SD
Q4 25
$480.2M
$644.0M
Q3 25
$506.9M
$619.0M
Q2 25
$372.7M
$602.3M
Q1 25
$386.7M
$588.3M
Q4 24
$392.3M
$581.5M
Q3 24
$363.6M
$565.2M
Q2 24
$381.8M
$529.6M
Q1 24
$258.7M
$527.4M

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
RYTM
RYTM
SD
SD
Operating Cash FlowLast quarter
$-25.4M
$31.7M
Free Cash FlowOCF − Capex
$14.4M
FCF MarginFCF / Revenue
36.6%
Capex IntensityCapex / Revenue
43.8%
Cash ConversionOCF / Net Profit
1.46×
TTM Free Cash FlowTrailing 4 quarters
$41.5M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
RYTM
RYTM
SD
SD
Q4 25
$-25.4M
$31.7M
Q3 25
$-26.6M
$25.3M
Q2 25
$-23.3M
$22.9M
Q1 25
$-40.4M
$20.3M
Q4 24
$-18.8M
$26.0M
Q3 24
$-25.2M
$20.8M
Q2 24
$-29.1M
$11.4M
Q1 24
$-40.7M
$15.7M
Free Cash Flow
RYTM
RYTM
SD
SD
Q4 25
$14.4M
Q3 25
$5.9M
Q2 25
$7.3M
Q1 25
$13.9M
Q4 24
$13.2M
Q3 24
$10.8M
Q2 24
$9.0M
Q1 24
$14.6M
FCF Margin
RYTM
RYTM
SD
SD
Q4 25
36.6%
Q3 25
14.9%
Q2 25
21.0%
Q1 25
32.7%
Q4 24
33.8%
Q3 24
36.1%
Q2 24
34.5%
Q1 24
48.1%
Capex Intensity
RYTM
RYTM
SD
SD
Q4 25
43.8%
Q3 25
48.6%
Q2 25
45.2%
Q1 25
15.0%
Q4 24
32.9%
Q3 24
33.3%
Q2 24
9.4%
Q1 24
3.7%
Cash Conversion
RYTM
RYTM
SD
SD
Q4 25
1.46×
Q3 25
1.58×
Q2 25
1.17×
Q1 25
1.56×
Q4 24
1.48×
Q3 24
0.82×
Q2 24
1.30×
Q1 24
1.41×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

RYTM
RYTM

Segment breakdown not available.

SD
SD

Oil Reserves$19.0M48%
Natural Gas Reserves$11.6M30%
Natural Gas Liquids Reserves$8.7M22%

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