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Side-by-side financial comparison of Simulations Plus, Inc. (SLP) and Usio, Inc. (USIO). Click either name above to swap in a different company.

Usio, Inc. is the larger business by last-quarter revenue ($22.2M vs $18.4M, roughly 1.2× Simulations Plus, Inc.). Simulations Plus, Inc. runs the higher net margin — 3.7% vs -6.7%, a 10.4% gap on every dollar of revenue. On growth, Usio, Inc. posted the faster year-over-year revenue change (8.2% vs -2.7%). Over the past eight quarters, Usio, Inc.'s revenue compounded faster (3.0% CAGR vs 0.3%).

Simulations Plus, Inc. develops absorption, distribution, metabolism, excretion, and toxicity (ADMET) modeling and simulation software for the pharmaceutical and biotechnology, industrial chemicals, cosmetics, food ingredients, and herbicide industries. In September 2014, the company acquired Cognigen Corporation, a provider of clinical trial data analysis and consulting services.

Usio, Inc. is an American financial technology company headquartered in San Antonio, Texas. It provides integrated electronic payment services, including ACH processing, credit card and debit card acceptance, payment facilitation for software platforms, prepaid card issuing and a document print and mail operation.

SLP vs USIO — Head-to-Head

Bigger by revenue
USIO
USIO
1.2× larger
USIO
$22.2M
$18.4M
SLP
Growing faster (revenue YoY)
USIO
USIO
+10.8% gap
USIO
8.2%
-2.7%
SLP
Higher net margin
SLP
SLP
10.4% more per $
SLP
3.7%
-6.7%
USIO
Faster 2-yr revenue CAGR
USIO
USIO
Annualised
USIO
3.0%
0.3%
SLP

Income Statement — Q1 FY2026 vs Q4 FY2025

Metric
SLP
SLP
USIO
USIO
Revenue
$18.4M
$22.2M
Net Profit
$676.0K
$-1.5M
Gross Margin
59.1%
21.9%
Operating Margin
3.9%
-5.7%
Net Margin
3.7%
-6.7%
Revenue YoY
-2.7%
8.2%
Net Profit YoY
228.2%
-337.8%
EPS (diluted)
$0.03
$-0.05

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
SLP
SLP
USIO
USIO
Q4 25
$18.4M
$22.2M
Q3 25
$17.5M
$21.2M
Q2 25
$20.4M
$20.0M
Q1 25
$22.4M
$22.0M
Q4 24
$18.9M
$20.6M
Q3 24
$18.7M
$21.3M
Q2 24
$18.5M
$20.1M
Q1 24
$18.3M
$21.0M
Net Profit
SLP
SLP
USIO
USIO
Q4 25
$676.0K
$-1.5M
Q3 25
$-681.0K
$-415.1K
Q2 25
$-67.3M
$-366.7K
Q1 25
$3.1M
$-235.0K
Q4 24
$206.0K
$628.9K
Q3 24
$843.0K
$2.9M
Q2 24
$3.1M
$75.5K
Q1 24
$4.0M
$-250.2K
Gross Margin
SLP
SLP
USIO
USIO
Q4 25
59.1%
21.9%
Q3 25
56.4%
23.0%
Q2 25
64.0%
25.8%
Q1 25
58.5%
21.9%
Q4 24
54.0%
24.6%
Q3 24
36.6%
23.0%
Q2 24
71.5%
23.9%
Q1 24
72.2%
23.1%
Operating Margin
SLP
SLP
USIO
USIO
Q4 25
3.9%
-5.7%
Q3 25
3.8%
-2.2%
Q2 25
-364.5%
-2.0%
Q1 25
12.1%
-1.1%
Q4 24
0.7%
-2.9%
Q3 24
-6.2%
-1.8%
Q2 24
10.1%
-1.0%
Q1 24
24.3%
-1.3%
Net Margin
SLP
SLP
USIO
USIO
Q4 25
3.7%
-6.7%
Q3 25
-3.9%
-2.0%
Q2 25
-330.6%
-1.8%
Q1 25
13.7%
-1.1%
Q4 24
1.1%
3.1%
Q3 24
4.5%
13.4%
Q2 24
16.9%
0.4%
Q1 24
22.0%
-1.2%
EPS (diluted)
SLP
SLP
USIO
USIO
Q4 25
$0.03
$-0.05
Q3 25
$-0.03
$-0.02
Q2 25
$-3.35
$-0.01
Q1 25
$0.15
$-0.01
Q4 24
$0.01
$0.03
Q3 24
$0.04
$0.10
Q2 24
$0.15
$0.00
Q1 24
$0.20
$-0.01

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
SLP
SLP
USIO
USIO
Cash + ST InvestmentsLiquidity on hand
$35.7M
$7.4M
Total DebtLower is stronger
$1.4M
Stockholders' EquityBook value
$127.1M
$17.9M
Total Assets
$137.8M
$134.9M
Debt / EquityLower = less leverage
0.08×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
SLP
SLP
USIO
USIO
Q4 25
$35.7M
$7.4M
Q3 25
$32.4M
$7.7M
Q2 25
$28.4M
$8.1M
Q1 25
$21.4M
$8.7M
Q4 24
$18.2M
$8.1M
Q3 24
$20.3M
$8.4M
Q2 24
$119.0M
$7.2M
Q1 24
$108.5M
$7.1M
Total Debt
SLP
SLP
USIO
USIO
Q4 25
$1.4M
Q3 25
$836.7K
Q2 25
$647.1K
Q1 25
$683.3K
Q4 24
$719.4K
Q3 24
$562.9K
Q2 24
$597.2K
Q1 24
$630.9K
Stockholders' Equity
SLP
SLP
USIO
USIO
Q4 25
$127.1M
$17.9M
Q3 25
$124.8M
$18.7M
Q2 25
$123.8M
$18.7M
Q1 25
$189.5M
$19.0M
Q4 24
$184.7M
$19.2M
Q3 24
$182.4M
$18.9M
Q2 24
$180.9M
$15.7M
Q1 24
$177.0M
$15.3M
Total Assets
SLP
SLP
USIO
USIO
Q4 25
$137.8M
$134.9M
Q3 25
$131.9M
$99.4M
Q2 25
$134.4M
$108.4M
Q1 25
$201.4M
$109.6M
Q4 24
$196.9M
$107.2M
Q3 24
$196.6M
$114.6M
Q2 24
$192.7M
$108.8M
Q1 24
$194.0M
$99.1M
Debt / Equity
SLP
SLP
USIO
USIO
Q4 25
0.08×
Q3 25
0.04×
Q2 25
0.03×
Q1 25
0.04×
Q4 24
0.04×
Q3 24
0.03×
Q2 24
0.04×
Q1 24
0.04×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
SLP
SLP
USIO
USIO
Operating Cash FlowLast quarter
$4.2M
$1.5M
Free Cash FlowOCF − Capex
$1.1M
FCF MarginFCF / Revenue
4.8%
Capex IntensityCapex / Revenue
0.0%
2.0%
Cash ConversionOCF / Net Profit
6.26×
TTM Free Cash FlowTrailing 4 quarters
$1.7M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
SLP
SLP
USIO
USIO
Q4 25
$4.2M
$1.5M
Q3 25
$5.6M
$303.8K
Q2 25
$8.1M
$-263.9K
Q1 25
$5.7M
$1.4M
Q4 24
$-1.3M
$2.9M
Q3 24
$1.7M
$1.4M
Q2 24
$5.7M
$369.1K
Q1 24
$5.8M
$88.7K
Free Cash Flow
SLP
SLP
USIO
USIO
Q4 25
$1.1M
Q3 25
$5.3M
$85.2K
Q2 25
$7.8M
$-503.2K
Q1 25
$5.6M
$1.1M
Q4 24
$-1.4M
$2.7M
Q3 24
$1.6M
$1.4M
Q2 24
$5.6M
$246.3K
Q1 24
$5.4M
$-88.1K
FCF Margin
SLP
SLP
USIO
USIO
Q4 25
4.8%
Q3 25
30.5%
0.4%
Q2 25
38.5%
-2.5%
Q1 25
25.0%
4.8%
Q4 24
-7.2%
13.1%
Q3 24
8.8%
6.4%
Q2 24
30.0%
1.2%
Q1 24
29.4%
-0.4%
Capex Intensity
SLP
SLP
USIO
USIO
Q4 25
0.0%
2.0%
Q3 25
1.5%
1.0%
Q2 25
1.5%
1.2%
Q1 25
0.3%
1.4%
Q4 24
0.5%
1.0%
Q3 24
0.1%
0.3%
Q2 24
0.6%
0.6%
Q1 24
2.4%
0.8%
Cash Conversion
SLP
SLP
USIO
USIO
Q4 25
6.26×
Q3 25
Q2 25
Q1 25
1.84×
Q4 24
-6.18×
4.61×
Q3 24
1.97×
0.50×
Q2 24
1.81×
4.89×
Q1 24
1.44×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

SLP
SLP

Services Segment$9.5M52%
Development$7.2M39%
Discovery$1.3M7%

USIO
USIO

Credit Card Revenue$7.7M35%
ACH And Complementary Service Revenue$6.1M28%
Output Solutions$5.4M24%
Prepaid Card Services Revenue$2.6M12%

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