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Side-by-side financial comparison of Spire Global, Inc. (SPIR) and TriSalus Life Sciences, Inc. (TLSI). Click either name above to swap in a different company.
Spire Global, Inc. is the larger business by last-quarter revenue ($15.8M vs $13.2M, roughly 1.2× TriSalus Life Sciences, Inc.). TriSalus Life Sciences, Inc. runs the higher net margin — -73.9% vs -176.6%, a 102.8% gap on every dollar of revenue. On growth, TriSalus Life Sciences, Inc. posted the faster year-over-year revenue change (59.8% vs -26.9%). TriSalus Life Sciences, Inc. produced more free cash flow last quarter ($-2.5M vs $-16.2M). Over the past eight quarters, TriSalus Life Sciences, Inc.'s revenue compounded faster (43.0% CAGR vs -32.6%).
Spire Global, Inc. is a space-to-cloud data and analytics company that specializes in the tracking of global data sets powered by a large constellation of nanosatellites, such as the tracking of maritime, aviation and weather patterns.
TriSalus Life Sciences, Inc. is a clinical-stage biotechnology company focused on advancing immuno-oncology and interventional oncology solutions. It develops proprietary targeted drug delivery technologies designed to improve treatment efficacy for patients with liver, pancreatic and other hard-to-treat solid tumors, primarily operating in North American markets via partnerships with clinical care and research institutions.
SPIR vs TLSI — Head-to-Head
Income Statement — Q4 FY2025 vs Q4 FY2025
| Metric | | |
|---|---|---|
| Revenue | $15.8M | $13.2M |
| Net Profit | $-28.0M | $-9.8M |
| Gross Margin | 40.2% | 86.7% |
| Operating Margin | -164.1% | -24.8% |
| Net Margin | -176.6% | -73.9% |
| Revenue YoY | -26.9% | 59.8% |
| Net Profit YoY | 42.7% | 3.5% |
| EPS (diluted) | $-0.85 | $-0.22 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q4 25 | $15.8M | $13.2M | ||
| Q3 25 | $12.7M | $11.6M | ||
| Q2 25 | $19.2M | $11.2M | ||
| Q1 25 | $23.9M | $9.2M | ||
| Q4 24 | $21.7M | $8.3M | ||
| Q3 24 | $28.6M | $7.3M | ||
| Q2 24 | $25.4M | $7.4M | ||
| Q1 24 | $34.8M | $6.5M |
| Q4 25 | $-28.0M | $-9.8M | ||
| Q3 25 | $-19.7M | $-10.8M | ||
| Q2 25 | $119.6M | $-8.3M | ||
| Q1 25 | $-20.7M | $-10.4M | ||
| Q4 24 | $-48.8M | $-10.1M | ||
| Q3 24 | $-12.5M | $-2.4M | ||
| Q2 24 | $-16.6M | $-4.3M | ||
| Q1 24 | $-25.5M | $-13.2M |
| Q4 25 | 40.2% | 86.7% | ||
| Q3 25 | 36.6% | 83.5% | ||
| Q2 25 | 48.9% | 83.9% | ||
| Q1 25 | 36.8% | 83.7% | ||
| Q4 24 | 32.4% | 85.3% | ||
| Q3 24 | 44.5% | 86.3% | ||
| Q2 24 | 43.0% | 87.6% | ||
| Q1 24 | 26.5% | 85.0% |
| Q4 25 | -164.1% | -24.8% | ||
| Q3 25 | -166.1% | -77.9% | ||
| Q2 25 | -122.7% | -65.4% | ||
| Q1 25 | -106.5% | -79.9% | ||
| Q4 24 | -144.1% | -91.8% | ||
| Q3 24 | -48.0% | -118.9% | ||
| Q2 24 | -48.6% | -111.0% | ||
| Q1 24 | -34.4% | -180.8% |
| Q4 25 | -176.6% | -73.9% | ||
| Q3 25 | -155.3% | -93.5% | ||
| Q2 25 | 623.4% | -73.9% | ||
| Q1 25 | -86.5% | -113.2% | ||
| Q4 24 | -225.2% | -122.4% | ||
| Q3 24 | -43.7% | -32.6% | ||
| Q2 24 | -65.2% | -58.8% | ||
| Q1 24 | -73.3% | -204.5% |
| Q4 25 | $-0.85 | $-0.22 | ||
| Q3 25 | $-0.61 | $-0.96 | ||
| Q2 25 | $3.72 | $-0.27 | ||
| Q1 25 | $-0.77 | $-0.39 | ||
| Q4 24 | $-1.93 | $-0.38 | ||
| Q3 24 | $-0.50 | $-0.12 | ||
| Q2 24 | $-0.68 | $-0.21 | ||
| Q1 24 | $-1.17 | $-0.60 |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $81.8M | $20.4M |
| Total DebtLower is stronger | — | — |
| Stockholders' EquityBook value | $112.9M | $-33.9M |
| Total Assets | $211.0M | $35.3M |
| Debt / EquityLower = less leverage | — | — |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $81.8M | $20.4M | ||
| Q3 25 | $96.8M | $22.7M | ||
| Q2 25 | $117.6M | $26.5M | ||
| Q1 25 | $35.9M | $13.0M | ||
| Q4 24 | $19.2M | $8.5M | ||
| Q3 24 | $36.6M | $11.3M | ||
| Q2 24 | $45.8M | $16.5M | ||
| Q1 24 | $63.7M | $4.0M |
| Q4 25 | — | — | ||
| Q3 25 | — | — | ||
| Q2 25 | — | — | ||
| Q1 25 | $103.7M | — | ||
| Q4 24 | $103.1M | — | ||
| Q3 24 | $4.9M | — | ||
| Q2 24 | $4.9M | — | ||
| Q1 24 | $123.1M | — |
| Q4 25 | $112.9M | $-33.9M | ||
| Q3 25 | $133.1M | $-26.7M | ||
| Q2 25 | $149.2M | $-19.4M | ||
| Q1 25 | $3.7M | $-34.4M | ||
| Q4 24 | $-11.7M | $-25.9M | ||
| Q3 24 | $30.8M | $-20.4M | ||
| Q2 24 | $40.3M | $-25.3M | ||
| Q1 24 | $52.5M | $-36.0M |
| Q4 25 | $211.0M | $35.3M | ||
| Q3 25 | $224.3M | $36.5M | ||
| Q2 25 | $239.5M | $41.3M | ||
| Q1 25 | $208.8M | $28.6M | ||
| Q4 24 | $193.6M | $24.0M | ||
| Q3 24 | $224.2M | $27.5M | ||
| Q2 24 | $230.8M | $32.4M | ||
| Q1 24 | $252.3M | $17.9M |
| Q4 25 | — | — | ||
| Q3 25 | — | — | ||
| Q2 25 | — | — | ||
| Q1 25 | 27.92× | — | ||
| Q4 24 | — | — | ||
| Q3 24 | 0.16× | — | ||
| Q2 24 | 0.12× | — | ||
| Q1 24 | 2.35× | — |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | $-4.3M | $-2.5M |
| Free Cash FlowOCF − Capex | $-16.2M | $-2.5M |
| FCF MarginFCF / Revenue | -102.1% | -19.1% |
| Capex IntensityCapex / Revenue | 75.1% | 0.3% |
| Cash ConversionOCF / Net Profit | — | — |
| TTM Free Cash FlowTrailing 4 quarters | $-92.6M | $-19.1M |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $-4.3M | $-2.5M | ||
| Q3 25 | $-12.0M | $-3.7M | ||
| Q2 25 | $-35.1M | $-7.3M | ||
| Q1 25 | $-8.4M | $-4.5M | ||
| Q4 24 | $-19.2M | $-5.7M | ||
| Q3 24 | $14.0M | $-10.8M | ||
| Q2 24 | $-4.4M | $-13.4M | ||
| Q1 24 | $-8.8M | $-10.9M |
| Q4 25 | $-16.2M | $-2.5M | ||
| Q3 25 | $-20.4M | $-3.9M | ||
| Q2 25 | $-38.7M | $-7.4M | ||
| Q1 25 | $-17.3M | $-5.3M | ||
| Q4 24 | $-24.3M | $-5.8M | ||
| Q3 24 | $5.1M | $-11.0M | ||
| Q2 24 | $-9.9M | $-13.5M | ||
| Q1 24 | $-15.9M | $-10.9M |
| Q4 25 | -102.1% | -19.1% | ||
| Q3 25 | -161.3% | -33.9% | ||
| Q2 25 | -201.7% | -66.1% | ||
| Q1 25 | -72.6% | -57.3% | ||
| Q4 24 | -112.2% | -69.7% | ||
| Q3 24 | 17.8% | -149.9% | ||
| Q2 24 | -39.0% | -183.1% | ||
| Q1 24 | -45.7% | -169.3% |
| Q4 25 | 75.1% | 0.3% | ||
| Q3 25 | 66.2% | 1.9% | ||
| Q2 25 | 18.8% | 0.8% | ||
| Q1 25 | 37.3% | 8.2% | ||
| Q4 24 | 23.5% | 0.6% | ||
| Q3 24 | 31.2% | 2.3% | ||
| Q2 24 | 21.8% | 0.8% | ||
| Q1 24 | 20.3% | 1.0% |
| Q4 25 | — | — | ||
| Q3 25 | — | — | ||
| Q2 25 | -0.29× | — | ||
| Q1 25 | — | — | ||
| Q4 24 | — | — | ||
| Q3 24 | — | — | ||
| Q2 24 | — | — | ||
| Q1 24 | — | — |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
