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Side-by-side financial comparison of Twist Bioscience Corp (TWST) and Vitesse Energy, Inc. (VTS). Click either name above to swap in a different company.

Twist Bioscience Corp is the larger business by last-quarter revenue ($103.7M vs $58.6M, roughly 1.8× Vitesse Energy, Inc.). Vitesse Energy, Inc. runs the higher net margin — -1.3% vs -29.4%, a 28.2% gap on every dollar of revenue. On growth, Twist Bioscience Corp posted the faster year-over-year revenue change (16.9% vs 4.8%).

Twist Bioscience is a public biotechnology company based in South San Francisco that manufactures synthetic DNA and DNA products for customers in a wide range of industries. Twist was founded in 2013 by Emily Leproust, Bill Banyai, and Bill Peck.

Vitesse Energy, Inc. is a U.S.-headquartered independent energy company focused on exploration, development, and production of oil and natural gas assets. It operates primarily in high-potential onshore basins including North Dakota's Williston Basin, serving domestic and global upstream energy market demand.

TWST vs VTS — Head-to-Head

Bigger by revenue
TWST
TWST
1.8× larger
TWST
$103.7M
$58.6M
VTS
Growing faster (revenue YoY)
TWST
TWST
+12.1% gap
TWST
16.9%
4.8%
VTS
Higher net margin
VTS
VTS
28.2% more per $
VTS
-1.3%
-29.4%
TWST

Income Statement — Q1 FY2026 vs Q4 FY2025

Metric
TWST
TWST
VTS
VTS
Revenue
$103.7M
$58.6M
Net Profit
$-30.5M
$-739.0K
Gross Margin
52.0%
Operating Margin
-31.7%
-12.0%
Net Margin
-29.4%
-1.3%
Revenue YoY
16.9%
4.8%
Net Profit YoY
3.4%
85.6%
EPS (diluted)
$-0.50
$-0.01

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
TWST
TWST
VTS
VTS
Q4 25
$103.7M
$58.6M
Q3 25
$67.4M
Q2 25
$81.8M
Q1 25
$66.2M
Q4 24
$55.9M
Q3 24
$58.3M
Q2 24
$66.6M
Q1 24
$61.2M
Net Profit
TWST
TWST
VTS
VTS
Q4 25
$-30.5M
$-739.0K
Q3 25
$-1.3M
Q2 25
$24.7M
Q1 25
$2.7M
Q4 24
$-5.1M
Q3 24
$17.4M
Q2 24
$10.9M
Q1 24
$-2.2M
Gross Margin
TWST
TWST
VTS
VTS
Q4 25
52.0%
Q3 25
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24
Operating Margin
TWST
TWST
VTS
VTS
Q4 25
-31.7%
-12.0%
Q3 25
0.2%
Q2 25
22.8%
Q1 25
8.1%
Q4 24
3.7%
Q3 24
15.4%
Q2 24
25.2%
Q1 24
21.4%
Net Margin
TWST
TWST
VTS
VTS
Q4 25
-29.4%
-1.3%
Q3 25
-1.9%
Q2 25
30.2%
Q1 25
4.0%
Q4 24
-9.2%
Q3 24
29.9%
Q2 24
16.4%
Q1 24
-3.6%
EPS (diluted)
TWST
TWST
VTS
VTS
Q4 25
$-0.50
$-0.01
Q3 25
$-0.03
Q2 25
$0.60
Q1 25
$0.08
Q4 24
$-0.15
Q3 24
$0.53
Q2 24
$0.33
Q1 24
$-0.07

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
TWST
TWST
VTS
VTS
Cash + ST InvestmentsLiquidity on hand
$197.9M
Total DebtLower is stronger
Stockholders' EquityBook value
$456.1M
$629.3M
Total Assets
$638.1M
$893.4M
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
TWST
TWST
VTS
VTS
Q4 25
$197.9M
Q3 25
Q2 25
Q1 25
$4.5M
Q4 24
$3.0M
Q3 24
Q2 24
Q1 24
Stockholders' Equity
TWST
TWST
VTS
VTS
Q4 25
$456.1M
$629.3M
Q3 25
$650.3M
Q2 25
$671.9M
Q1 25
$667.7M
Q4 24
$500.3M
Q3 24
$520.4M
Q2 24
$518.5M
Q1 24
$522.7M
Total Assets
TWST
TWST
VTS
VTS
Q4 25
$638.1M
$893.4M
Q3 25
$932.9M
Q2 25
$951.5M
Q1 25
$975.2M
Q4 24
$810.9M
Q3 24
$791.2M
Q2 24
$778.4M
Q1 24
$749.7M

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
TWST
TWST
VTS
VTS
Operating Cash FlowLast quarter
$-24.8M
$37.4M
Free Cash FlowOCF − Capex
$-34.8M
FCF MarginFCF / Revenue
-33.5%
Capex IntensityCapex / Revenue
9.6%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
TWST
TWST
VTS
VTS
Q4 25
$-24.8M
$37.4M
Q3 25
$49.4M
Q2 25
$66.0M
Q1 25
$17.5M
Q4 24
$34.7M
Q3 24
$45.7M
Q2 24
$35.2M
Q1 24
$39.4M
Free Cash Flow
TWST
TWST
VTS
VTS
Q4 25
$-34.8M
Q3 25
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24
FCF Margin
TWST
TWST
VTS
VTS
Q4 25
-33.5%
Q3 25
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24
Capex Intensity
TWST
TWST
VTS
VTS
Q4 25
9.6%
Q3 25
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24
Cash Conversion
TWST
TWST
VTS
VTS
Q4 25
Q3 25
Q2 25
2.68×
Q1 25
6.56×
Q4 24
Q3 24
2.62×
Q2 24
3.22×
Q1 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

TWST
TWST

Industrial Chemicals$37.2M36%
Diagnostics$35.3M34%
Food Or Agriculture$12.8M12%
Academic Research$12.2M12%
Health Care$6.1M6%

VTS
VTS

Oil Reserves$54.5M93%
Natural Gas Reserves$4.2M7%

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