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Side-by-side financial comparison of Lilly (Eli) (LLY) and Merck & Co. (MRK), based on the latest 10-Q / 10-K filings. Click either name above to swap in a different company.
Lilly (Eli) is the larger business by last-quarter revenue ($19.3B vs $16.4B, roughly 1.2× Merck & Co.). Lilly (Eli) runs the higher net margin — 34.4% vs 18.1%, a 16.3% gap on every dollar of revenue. On growth, Lilly (Eli) posted the faster year-over-year revenue change (42.6% vs 5.0%). Over the past eight quarters, Lilly (Eli)'s revenue compounded faster (48.3% CAGR vs 2.0%).
Eli Lilly and Company, doing business as Lilly, is an American multinational pharmaceutical company headquartered in Indianapolis, Indiana, with offices in 18 countries. Its products are sold in approximately 125 countries. The company was founded in 1876 by Eli Lilly, a pharmaceutical chemist and Union army veteran during the American Civil War for whom the company was later named.
Merck & Co., Inc. is an American multinational pharmaceutical company headquartered in Rahway, New Jersey. The company does business as Merck Sharp & Dohme or MSD outside the United States and Canada. The company is ranked fourth on the list of largest biomedical companies by revenue.
LLY vs MRK — Head-to-Head
Income Statement — Q4 2025 vs Q4 2025
| Metric | | |
|---|---|---|
| Revenue | $19.3B | $16.4B |
| Net Profit | $6.6B | $3.0B |
| Gross Margin | 82.5% | 66.2% |
| Operating Margin | 42.8% | 20.9% |
| Net Margin | 34.4% | 18.1% |
| Revenue YoY | 42.6% | 5.0% |
| Net Profit YoY | 50.5% | -20.8% |
| EPS (diluted) | $7.39 | $1.19 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align — see 8-quarter trend below.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history — bar widths are scaled to the larger of the two companies so you can eyeball the size gap and growth trajectory without doing math. Quarters aligned by calendar period (report date) so offset fiscal years line up.
| Q4 25 | $19.3B | $16.4B | ||
| Q3 25 | $17.6B | $17.3B | ||
| Q2 25 | $15.6B | $15.8B | ||
| Q1 25 | $12.7B | $15.5B | ||
| Q4 24 | $13.5B | $15.6B | ||
| Q3 24 | $11.4B | $16.7B | ||
| Q2 24 | $11.3B | $16.1B | ||
| Q1 24 | $8.8B | $15.8B |
| Q4 25 | $6.6B | $3.0B | ||
| Q3 25 | $5.6B | $5.8B | ||
| Q2 25 | $5.7B | $4.4B | ||
| Q1 25 | $2.8B | $5.1B | ||
| Q4 24 | $4.4B | $3.7B | ||
| Q3 24 | $970.3M | $3.2B | ||
| Q2 24 | $3.0B | $5.5B | ||
| Q1 24 | $2.2B | $4.8B |
| Q4 25 | 82.5% | 66.2% | ||
| Q3 25 | 82.9% | 77.7% | ||
| Q2 25 | 84.3% | 77.5% | ||
| Q1 25 | 82.5% | 78.0% | ||
| Q4 24 | 82.2% | 75.5% | ||
| Q3 24 | 81.0% | 75.5% | ||
| Q2 24 | 80.8% | 76.8% | ||
| Q1 24 | 80.9% | 77.6% |
| Q4 25 | 42.8% | 20.9% | ||
| Q3 25 | 41.1% | 39.0% | ||
| Q2 25 | 43.6% | 31.6% | ||
| Q1 25 | 27.2% | 38.0% | ||
| Q4 24 | 37.2% | 26.7% | ||
| Q3 24 | 13.9% | 24.6% | ||
| Q2 24 | 31.1% | 37.3% | ||
| Q1 24 | 28.9% | 35.9% |
| Q4 25 | 34.4% | 18.1% | ||
| Q3 25 | 31.7% | 33.5% | ||
| Q2 25 | 36.4% | 28.0% | ||
| Q1 25 | 21.7% | 32.7% | ||
| Q4 24 | 32.6% | 24.0% | ||
| Q3 24 | 8.5% | 19.0% | ||
| Q2 24 | 26.3% | 33.9% | ||
| Q1 24 | 25.6% | 30.2% |
| Q4 25 | $7.39 | $1.19 | ||
| Q3 25 | $6.21 | $2.32 | ||
| Q2 25 | $6.29 | $1.76 | ||
| Q1 25 | $3.06 | $2.01 | ||
| Q4 24 | $4.88 | $1.49 | ||
| Q3 24 | $1.07 | $1.24 | ||
| Q2 24 | $3.28 | $2.14 | ||
| Q1 24 | $2.48 | $1.87 |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest filing — the kind of financial-strength check premium terminals charge for.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $7.3B | $14.6B |
| Total DebtLower is stronger | — | — |
| Stockholders' EquityBook value | $26.5B | $52.6B |
| Total Assets | $112.5B | $136.9B |
| Debt / EquityLower = less leverage | — | — |
8-quarter trend — quarters aligned by calendar period so offset fiscal years match up.
| Q4 25 | $7.3B | $14.6B | ||
| Q3 25 | $9.9B | $18.2B | ||
| Q2 25 | $3.5B | $8.6B | ||
| Q1 25 | $3.2B | $9.2B | ||
| Q4 24 | $3.4B | $13.7B | ||
| Q3 24 | $3.5B | $14.6B | ||
| Q2 24 | $3.4B | $11.4B | ||
| Q1 24 | $2.6B | $5.6B |
| Q4 25 | — | — | ||
| Q3 25 | — | — | ||
| Q2 25 | — | — | ||
| Q1 25 | — | — | ||
| Q4 24 | $29.5B | — | ||
| Q3 24 | — | — | ||
| Q2 24 | — | — | ||
| Q1 24 | — | — |
| Q4 25 | $26.5B | $52.6B | ||
| Q3 25 | $23.8B | $51.9B | ||
| Q2 25 | $18.3B | $49.0B | ||
| Q1 25 | $15.8B | $48.3B | ||
| Q4 24 | $14.2B | $46.3B | ||
| Q3 24 | $14.2B | $44.5B | ||
| Q2 24 | $13.6B | $43.6B | ||
| Q1 24 | $12.8B | $40.4B |
| Q4 25 | $112.5B | $136.9B | ||
| Q3 25 | $114.9B | $129.5B | ||
| Q2 25 | $100.9B | $117.5B | ||
| Q1 25 | $89.4B | $115.1B | ||
| Q4 24 | $78.7B | $117.1B | ||
| Q3 24 | $75.6B | $117.5B | ||
| Q2 24 | $71.9B | $112.6B | ||
| Q1 24 | $63.9B | $105.8B |
| Q4 25 | — | — | ||
| Q3 25 | — | — | ||
| Q2 25 | — | — | ||
| Q1 25 | — | — | ||
| Q4 24 | 2.08× | — | ||
| Q3 24 | — | — | ||
| Q2 24 | — | — | ||
| Q1 24 | — | — |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Net income can be massaged; cash flow is harder to fake.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | $3.2B | $2.9B |
| Free Cash FlowOCF − Capex | — | $1.8B |
| FCF MarginFCF / Revenue | — | 11.1% |
| Capex IntensityCapex / Revenue; lower = less reinvestment burden | — | 6.3% |
| Cash ConversionOCF / Net Profit; >1× = earnings back up with cash | 0.49× | 0.96× |
| TTM Free Cash FlowTrailing 4 quarters | — | $12.4B |
8-quarter trend — quarters aligned by calendar period so offset fiscal years match up.
| Q4 25 | $3.2B | $2.9B | ||
| Q3 25 | $8.8B | $7.8B | ||
| Q2 25 | $3.1B | $3.3B | ||
| Q1 25 | $1.7B | $2.5B | ||
| Q4 24 | $2.5B | $3.5B | ||
| Q3 24 | $3.7B | $9.3B | ||
| Q2 24 | $1.5B | $5.6B | ||
| Q1 24 | $1.2B | $3.1B |
| Q4 25 | — | $1.8B | ||
| Q3 25 | — | $6.8B | ||
| Q2 25 | — | $2.5B | ||
| Q1 25 | — | $1.2B | ||
| Q4 24 | — | $2.5B | ||
| Q3 24 | — | $8.5B | ||
| Q2 24 | — | $4.8B | ||
| Q1 24 | — | $2.2B |
| Q4 25 | — | 11.1% | ||
| Q3 25 | — | 39.6% | ||
| Q2 25 | — | 16.0% | ||
| Q1 25 | — | 7.5% | ||
| Q4 24 | — | 16.1% | ||
| Q3 24 | — | 51.1% | ||
| Q2 24 | — | 30.1% | ||
| Q1 24 | — | 14.1% |
| Q4 25 | — | 6.3% | ||
| Q3 25 | — | 5.7% | ||
| Q2 25 | — | 4.8% | ||
| Q1 25 | — | 8.6% | ||
| Q4 24 | — | 6.0% | ||
| Q3 24 | — | 4.7% | ||
| Q2 24 | — | 4.9% | ||
| Q1 24 | — | 5.5% |
| Q4 25 | 0.49× | 0.96× | ||
| Q3 25 | 1.58× | 1.35× | ||
| Q2 25 | 0.55× | 0.74× | ||
| Q1 25 | 0.60× | 0.49× | ||
| Q4 24 | 0.56× | 0.92× | ||
| Q3 24 | 3.83× | 2.94× | ||
| Q2 24 | 0.49× | 1.03× | ||
| Q1 24 | 0.52× | 0.65× |
Financial Flow Comparison
Sankey diagram of revenue → gross profit → operating profit → net profit for each company. Charts shown full-width and stacked so both segment hierarchies are readable side-by-side on desktop and mobile.
Revenue Breakdown by Segment
LLY
| Other | $5.4B | 28% |
| Zepbound | $4.2B | 22% |
| Mounjaro | $4.1B | 21% |
| Verzenio | $997.1M | 5% |
| Collaborationand Other Revenue | $991.7M | 5% |
| Taltz | $724.3M | 4% |
| Trulicity | $692.8M | 4% |
| Other Cardiometabolic Health | $524.5M | 3% |
| Other Oncology | $514.8M | 3% |
| Jardiance | $465.8M | 2% |
| Neuroscience | $320.2M | 2% |
| Other Immunology | $187.3M | 1% |
| Other Product Total | $77.0M | 0% |
MRK
| Pharmaceuticalsegment | $8.7B | 53% |
| Keytruda | $4.9B | 30% |
| Other | $2.7B | 16% |
| Janumet | $57.0M | 0% |
| Isentress Isentress HD | $38.0M | 0% |
| Pifeltro | $25.0M | 0% |
| Belsomra | $23.0M | 0% |
| Dificid | $17.0M | 0% |
| Delstrigo | $14.0M | 0% |
| Lagevrio | $12.0M | 0% |
| Pneumovax23 | $4.0M | 0% |
