10q10k10q10k.net

vs

Side-by-side financial comparison of AGIOS PHARMACEUTICALS, INC. (AGIO) and NOVARTIS AG (NVS), based on the latest 10-Q / 10-K filings. Click either name above to swap in a different company.

Agios Pharmaceuticals Inc. is a publicly trading American pharmaceutical company pioneering therapies for genetically defined diseases, with a near-term focus on developing therapies for hemolytic anemias. The company was founded in 2008 by Lewis Cantley, Tak Mak and Craig Thompson. Agios is a Delaware corporation headquartered in Cambridge, Massachusetts. The company tendered an initial public offering in July 2013.

Novartis AG is a Swiss multinational pharmaceutical corporation based in Basel, Switzerland. Novartis is one of the largest pharmaceutical companies in the world and was the eighth largest by revenue in 2024.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history — bar widths are scaled to the larger of the two companies so you can eyeball the size gap and growth trajectory without doing math. Quarters aligned by calendar period (report date) so offset fiscal years line up.

Revenue
AGIO
AGIO
NVS
NVS
Q4 25
$20.0M
Q3 25
$12.9M
Q2 25
$12.5M
Q1 25
$8.7M
Q4 24
$10.7M
Q3 24
$9.0M
Q2 24
$8.6M
Q1 24
$8.2M
Net Profit
AGIO
AGIO
NVS
NVS
Q4 25
$-108.0M
Q3 25
$-103.4M
Q2 25
$-112.0M
Q1 25
$-89.3M
Q4 24
$-96.5M
Q3 24
$947.9M
Q2 24
$-96.1M
Q1 24
$-81.5M
Gross Margin
AGIO
AGIO
NVS
NVS
Q4 25
90.6%
Q3 25
87.0%
Q2 25
86.3%
Q1 25
87.6%
Q4 24
88.3%
Q3 24
91.3%
Q2 24
82.6%
Q1 24
92.3%
Operating Margin
AGIO
AGIO
NVS
NVS
Q4 25
-608.9%
Q3 25
-907.4%
Q2 25
-1020.1%
Q1 25
-1222.0%
Q4 24
-1165.3%
Q3 24
-1146.9%
Q2 24
-1228.3%
Q1 24
-1124.3%
Net Margin
AGIO
AGIO
NVS
NVS
Q4 25
-541.1%
Q3 25
-803.1%
Q2 25
-899.4%
Q1 25
-1023.3%
Q4 24
-899.6%
Q3 24
10574.7%
Q2 24
-1115.7%
Q1 24
-995.8%
EPS (diluted)
AGIO
AGIO
NVS
NVS
Q4 25
$-1.86
Q3 25
$-1.78
Q2 25
$-1.93
Q1 25
$-1.55
Q4 24
$-1.44
Q3 24
$16.22
Q2 24
$-1.69
Q1 24
$-1.45

Financial Flow Comparison

Sankey diagram of revenue → gross profit → operating profit → net profit for each company. Charts shown full-width and stacked so both segment hierarchies are readable side-by-side on desktop and mobile.

Related Comparisons