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IONIS PHARMACEUTICALS INC（IONS）与BRC Group Holdings, Inc.（RILY）财务数据对比。点击上方公司名可切换其他公司
IONIS PHARMACEUTICALS INC的季度营收约是BRC Group Holdings, Inc.的1.1倍（$203.3M vs $188.3M），BRC Group Holdings, Inc.净利率更高（47.9% vs -112.8%，领先160.8%），IONIS PHARMACEUTICALS INC同比增速更快（-10.3% vs -21.9%），过去两年IONIS PHARMACEUTICALS INC的营收复合增速更高（30.4% vs -15.4%）
IONIS制药是1989年成立的生物科技企业，总部位于美国加利福尼亚州卡尔斯巴德，专注于反义疗法、RNA干扰及CRISPR疗法的研发，2015年12月前曾以Isis制药的名称运营。
IONS vs RILY — 直观对比
营收规模更大
IONS
是对方的1.1倍
$188.3M
营收增速更快
IONS
高出11.6%
-21.9%
净利率更高
RILY
高出160.8%
-112.8%
两年增速更快
IONS
近两年复合增速
-15.4%
损益表 — Q4 FY2025 vs Q4 FY2025
| 指标 | | |
|---|---|---|
| 营收 | $203.3M | $188.3M |
| 净利润 | $-229.4M | $90.3M |
| 毛利率 | 96.1% | 79.5% |
| 营业利润率 | -105.5% | 32.3% |
| 净利率 | -112.8% | 47.9% |
| 营收同比 | -10.3% | -21.9% |
| 净利润同比 | -119.8% | 1710.8% |
| 每股收益（稀释后） | $-1.35 | $2.78 |
绿色 = 该指标领先。财年不对齐时期间可能不同
8季度营收与利润趋势
并排季度历史对比，按日历期对齐，财年错位的公司也能正确匹配
营收IONSRILY
| Q4 25 | $203.3M | $188.3M | ||
| Q3 25 | $156.7M | $215.3M | ||
| Q2 25 | $452.0M | $188.2M | ||
| Q1 25 | $131.6M | $197.2M | ||
| Q4 24 | $226.6M | $241.0M | ||
| Q3 24 | $133.8M | $225.5M | ||
| Q2 24 | $225.3M | $256.0M | ||
| Q1 24 | $119.5M | $263.4M |
净利润IONSRILY
| Q4 25 | $-229.4M | $90.3M | ||
| Q3 25 | $-128.6M | $91.1M | ||
| Q2 25 | $123.6M | $139.5M | ||
| Q1 25 | $-146.9M | $-10.0M | ||
| Q4 24 | $-104.3M | $-5.6M | ||
| Q3 24 | $-140.5M | $-284.4M | ||
| Q2 24 | $-66.3M | $-433.6M | ||
| Q1 24 | $-142.8M | $-49.2M |
毛利率IONSRILY
| Q4 25 | 96.1% | 79.5% | ||
| Q3 25 | 98.5% | 83.7% | ||
| Q2 25 | 99.1% | 81.3% | ||
| Q1 25 | 98.9% | 81.4% | ||
| Q4 24 | 98.3% | 79.8% | ||
| Q3 24 | 99.2% | 82.1% | ||
| Q2 24 | 98.2% | 84.5% | ||
| Q1 24 | 98.2% | 85.3% |
营业利润率IONSRILY
| Q4 25 | -105.5% | 32.3% | ||
| Q3 25 | -102.2% | 30.4% | ||
| Q2 25 | 30.9% | 5.7% | ||
| Q1 25 | -111.6% | -31.2% | ||
| Q4 24 | -48.9% | -69.2% | ||
| Q3 24 | -111.1% | -36.4% | ||
| Q2 24 | -29.3% | -90.8% | ||
| Q1 24 | -125.1% | -6.1% |
净利率IONSRILY
| Q4 25 | -112.8% | 47.9% | ||
| Q3 25 | -82.1% | 42.3% | ||
| Q2 25 | 27.3% | 74.1% | ||
| Q1 25 | -111.6% | -5.1% | ||
| Q4 24 | -46.1% | -2.3% | ||
| Q3 24 | -105.0% | -126.1% | ||
| Q2 24 | -29.4% | -169.4% | ||
| Q1 24 | -119.5% | -18.7% |
每股收益（稀释后）IONSRILY
| Q4 25 | $-1.35 | $2.78 | ||
| Q3 25 | $-0.80 | $2.91 | ||
| Q2 25 | $0.70 | $4.50 | ||
| Q1 25 | $-0.93 | $-0.39 | ||
| Q4 24 | $-0.66 | $-0.01 | ||
| Q3 24 | $-0.95 | $-9.39 | ||
| Q2 24 | $-0.45 | $-14.35 | ||
| Q1 24 | $-0.98 | $-1.71 |
资产负债表与财务实力
最新季度各公司的流动性、杠杆与账面价值一览
| 指标 | | |
|---|---|---|
| 现金及短期投资手头流动性 | $2.7B | $226.6M |
| 总债务越低越好 | $1.8B | $1.4B |
| 股东权益账面价值 | $489.1M | $-171.5M |
| 总资产 | $3.5B | $1.7B |
| 负债/权益比越低杠杆越低 | 3.71× | — |
8季度趋势，按日历期对齐
现金及短期投资IONSRILY
| Q4 25 | $2.7B | $226.6M | ||
| Q3 25 | $2.2B | $184.2M | ||
| Q2 25 | $2.3B | $267.4M | ||
| Q1 25 | $2.1B | $138.3M | ||
| Q4 24 | $2.3B | $146.9M | ||
| Q3 24 | $2.5B | $159.2M | ||
| Q2 24 | $2.1B | $236.9M | ||
| Q1 24 | $2.2B | $190.7M |
总债务IONSRILY
| Q4 25 | $1.8B | $1.4B | ||
| Q3 25 | — | $1.3B | ||
| Q2 25 | — | $1.3B | ||
| Q1 25 | — | $1.4B | ||
| Q4 24 | $1.3B | $1.5B | ||
| Q3 24 | — | — | ||
| Q2 24 | — | — | ||
| Q1 24 | — | — |
股东权益IONSRILY
| Q4 25 | $489.1M | $-171.5M | ||
| Q3 25 | $618.0M | $-260.5M | ||
| Q2 25 | $631.7M | $-351.7M | ||
| Q1 25 | $475.7M | $-496.8M | ||
| Q4 24 | $588.4M | $-488.2M | ||
| Q3 24 | $662.5M | $-497.6M | ||
| Q2 24 | $263.7M | $-218.3M | ||
| Q1 24 | $296.5M | $228.4M |
总资产IONSRILY
| Q4 25 | $3.5B | $1.7B | ||
| Q3 25 | $3.0B | $1.7B | ||
| Q2 25 | $3.0B | $1.5B | ||
| Q1 25 | $2.8B | $1.5B | ||
| Q4 24 | $3.0B | $1.8B | ||
| Q3 24 | $3.1B | $2.2B | ||
| Q2 24 | $2.7B | $3.2B | ||
| Q1 24 | $2.8B | $5.0B |
负债/权益比IONSRILY
| Q4 25 | 3.71× | — | ||
| Q3 25 | — | — | ||
| Q2 25 | — | — | ||
| Q1 25 | — | — | ||
| Q4 24 | 2.13× | — | ||
| Q3 24 | — | — | ||
| Q2 24 | — | — | ||
| Q1 24 | — | — |
现金流与资本效率
扣除再投资后实际产生的现金。现金流比净利润更难造假
| 指标 | | |
|---|---|---|
| 经营现金流最新季度 | $-137.7M | $26.2M |
| 自由现金流经营现金流 - 资本支出 | $-159.0M | — |
| 自由现金流率自由现金流/营收 | -78.2% | — |
| 资本支出强度资本支出/营收 | 10.5% | — |
| 现金转化率经营现金流/净利润 | — | 0.29× |
| 过去12个月自由现金流最近4个季度 | $-320.0M | — |
8季度趋势，按日历期对齐
经营现金流IONSRILY
| Q4 25 | $-137.7M | $26.2M | ||
| Q3 25 | $-131.4M | $-60.6M | ||
| Q2 25 | $151.3M | $-25.6M | ||
| Q1 25 | $-150.8M | $184.0K | ||
| Q4 24 | $-116.1M | $-2.7M | ||
| Q3 24 | $-115.0M | $19.5M | ||
| Q2 24 | $-119.9M | $111.5M | ||
| Q1 24 | $-149.9M | $135.4M |
自由现金流IONSRILY
| Q4 25 | $-159.0M | — | ||
| Q3 25 | $-136.7M | — | ||
| Q2 25 | $139.0M | — | ||
| Q1 25 | $-163.4M | — | ||
| Q4 24 | $-141.6M | — | ||
| Q3 24 | $-124.0M | — | ||
| Q2 24 | $-126.1M | — | ||
| Q1 24 | $-154.4M | — |
自由现金流率IONSRILY
| Q4 25 | -78.2% | — | ||
| Q3 25 | -87.2% | — | ||
| Q2 25 | 30.8% | — | ||
| Q1 25 | -124.1% | — | ||
| Q4 24 | -62.5% | — | ||
| Q3 24 | -92.7% | — | ||
| Q2 24 | -56.0% | — | ||
| Q1 24 | -129.2% | — |
资本支出强度IONSRILY
| Q4 25 | 10.5% | — | ||
| Q3 25 | 3.4% | — | ||
| Q2 25 | 2.7% | — | ||
| Q1 25 | 9.6% | — | ||
| Q4 24 | 11.3% | — | ||
| Q3 24 | 6.8% | — | ||
| Q2 24 | 2.8% | — | ||
| Q1 24 | 3.8% | — |
现金转化率IONSRILY
| Q4 25 | — | 0.29× | ||
| Q3 25 | — | -0.66× | ||
| Q2 25 | 1.22× | -0.18× | ||
| Q1 25 | — | — | ||
| Q4 24 | — | — | ||
| Q3 24 | — | — | ||
| Q2 24 | — | — | ||
| Q1 24 | — | — |
财务流量对比
营收 → 毛利润 → 营业利润 → 净利润流向图
业务分部营收拆解
IONS
| Products | $58.0M | 29% |
| Spinraza Royalties | $54.0M | 27% |
| Collaborative Agreement Revenue | $52.4M | 26% |
| Wainus Royalties | $16.0M | 8% |
| Wainua Joint Development Revenue | $9.6M | 5% |
| Other Commercial | $7.6M | 4% |
| Other Royalties | $5.7M | 3% |
RILY
| Transferred At Point In Time | $101.4M | 54% |
| Wealth Management Segment | $30.7M | 16% |
| Corporate Finance Consulting And Investment Banking Fees | $27.1M | 14% |
| Services And Fees | $24.8M | 13% |
| Commissions Fees And Reimbursed Expenses | $4.8M | 3% |
