RHYTHM PHARMACEUTICALS, INC.

RHYTHM PHARMACEUTICALS, INC.RYTMEarnings & Financial Report

Nasdaq · Health Care · Pharmaceutical Preparations

Rhythm Pharmaceuticals is a biopharmaceutical firm focused on developing and commercializing targeted therapies for rare genetic disorders causing severe unmanageable obesity, including POMC deficiency, LEPR deficiency, and Bardet-Biedl syndrome. It serves patients in North America and Europe who lack effective standard treatments for their chronic life-altering conditions.

Revenue

$57.3M

Gross Profit

$52.5M

Operating Profit

$-47.1M

Net Profit

$-47.5M

Gross Margin

91.6%

Operating Margin

-82.2%

Net Margin

-83.0%

YoY Growth

36.9%

EPS

$-0.73

RHYTHM PHARMACEUTICALS, INC. Q4 FY2025 Financial Summary

RHYTHM PHARMACEUTICALS, INC. reported revenue of $57.3M (up 36.9% YoY) for Q4 FY2025, with a net profit of $-47.5M (down 9.6% YoY) (-83.0% margin). Cost of goods sold was $4.8M, operating expenses totaled $99.5M.

Key Financial Metrics

Total Revenue$57.3M
Net Profit$-47.5M
Gross Margin91.6%
Operating Margin-82.2%
Report PeriodQ4 FY2025

RHYTHM PHARMACEUTICALS, INC. Annual Revenue by Year

RHYTHM PHARMACEUTICALS, INC. annual revenue history includes year-by-year totals (for example, 2025 revenue was $189.8M).

YearAnnual Revenue
2025$189.8M
2024$130.1M
2023$77.4M

RHYTHM PHARMACEUTICALS, INC. Quarterly Revenue & Net Profit History

RHYTHM PHARMACEUTICALS, INC. results over the last 8 reported quarters, including revenue, net profit and year-over-year growth.

QuarterRevenueRevenue YoYNet ProfitNet Margin
Q1 FY2026$60.1M+83.8%$-55.6M-92.6%
Q4 FY2025$57.3M+36.9%$-47.5M-83.0%
Q3 FY2025$51.3M+54.3%$-52.9M-103.1%
Q2 FY2025$48.5M+66.8%$-46.6M-96.1%
Q1 FY2025$32.7M+25.9%$-49.5M-151.4%
Q4 FY2024$41.8M+72.6%$-43.3M-103.6%
Q3 FY2024$33.3M+47.8%$-43.6M-131.2%
Q2 FY2024$29.1M+51.3%$-32.3M-110.9%

Income Statement

Q2 2024Q3 2024Q4 2024Q1 2025Q2 2025Q3 2025Q4 2025Q1 2026
Revenue$29.1M$33.3M$41.8M$32.7M$48.5M$51.3M$57.3M$60.1M
YoY Growth51.3%47.8%72.6%25.9%66.8%54.3%36.9%83.8%

Balance Sheet

Q2 2024Q3 2024Q4 2024Q1 2025Q2 2025Q3 2025Q4 2025Q1 2026
Assets$381.8M$363.6M$392.3M$386.7M$372.7M$506.9M$480.2M$442.3M
Liabilities$202.4M$210.9M$227.7M$223.6M$239.2M$211.2M$210.2M$204.7M
Equity$39.3M$11.2M$21.7M$18.9M$-11.9M$148.8M$139.1M$122.9M

Cash Flow

Q2 2024Q3 2024Q4 2024Q1 2025Q2 2025Q3 2025Q4 2025
Operating CF$-29.1M$-25.2M$-18.8M$-40.4M$-23.3M$-26.6M$-25.4M