SPRUCE BIOSCIENCES, INC.

SPRUCE BIOSCIENCES, INC.SPRBEarnings & Financial Report

Nasdaq · Health Care · Pharmaceutical Preparations

Spruce Biosciences, Inc. is a late-stage biopharmaceutical firm focused on developing targeted therapies for rare endocrine and metabolic disorders with high unmet medical need. Its core pipeline includes candidates for congenital adrenal hyperplasia and Cushing’s syndrome, serving patients across North America, Europe and other developed markets.

SPRB Q4 FY2025 Key Financial Metrics

Revenue

$0

Gross Profit

N/A

Operating Profit

$-11.1M

Net Profit

$-14.6M

Gross Margin

N/A

Operating Margin

N/A

Net Margin

N/A

YoY Growth

N/A

EPS

$-32.43

SPRUCE BIOSCIENCES, INC. Q4 FY2025 Financial Summary

SPRUCE BIOSCIENCES, INC. reported revenue of $0 for Q4 FY2025, with a net profit of $-14.6M (up 37.8% YoY) (N/A margin).

Key Financial Metrics

Total Revenue$0
Net Profit$-14.6M
Gross MarginN/A
Operating MarginN/A
Report PeriodQ4 FY2025

SPRUCE BIOSCIENCES, INC. Annual Revenue by Year

SPRUCE BIOSCIENCES, INC. annual revenue history includes year-by-year totals (for example, 2025 revenue was $0).

YearAnnual Revenue
2025$0vs 2024
2024$4.9Mvs 2023
2023$10.1Mvs 2022
2022$0

SPRUCE BIOSCIENCES, INC. Quarterly Revenue & Net Profit History

SPRUCE BIOSCIENCES, INC. results over the last 8 reported quarters, including revenue, net profit and year-over-year growth.

QuarterRevenueRevenue YoYNet ProfitNet Margin
Q4 FY2025$0$-14.6MN/A
Q3 FY2025$0$-8.2MN/A
Q2 FY2025$0$-2.1MN/A
Q1 FY2025$0$-14.0MN/A
Q4 FY2024$697.0K-75.9%$-23.6M-3380.1%
Q3 FY2024$602.0K-80.4%$-8.7M-1440.4%
Q2 FY2024$1.6M-25.6%$-9.2M-570.2%
Q1 FY2024$2.0M+1.9%$-11.6M-580.7%

Income Statement

Q1 2024Q2 2024Q3 2024Q4 2024Q1 2025Q2 2025Q3 2025Q4 2025
Revenue$2.0M$1.6M$602000$697000$0$0$0$0
YoY Growth1.9%-25.6%-80.4%-75.9%N/AN/AN/AN/A

Balance Sheet

Q1 2024Q2 2024Q3 2024Q4 2024Q1 2025Q2 2025Q3 2025Q4 2025
Assets$87.5M$75.5M$65.1M$45.2M$31.6M$21.8M$15.3M$53.0M
Liabilities$20.9M$16.4M$13.5M$16.4M$16.3M$8.6M$9.9M$10.5M
Equity$66.6M$59.2M$51.6M$28.8M$15.3M$13.2M$5.4M$42.5M

Cash Flow

Q1 2024Q2 2024Q3 2024Q4 2024Q1 2025Q2 2025Q3 2025Q4 2025
Operating CF$-15.0M$-11.1M$-9.2M$-20.7M$-12.7M$-8.8M$-5.3M$-6.5M