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Side-by-side financial comparison of ACADIA PHARMACEUTICALS INC (ACAD) and PROSPERITY BANCSHARES INC (PB). Click either name above to swap in a different company.
PROSPERITY BANCSHARES INC is the larger business by last-quarter revenue ($367.6M vs $284.0M, roughly 1.3× ACADIA PHARMACEUTICALS INC). ACADIA PHARMACEUTICALS INC runs the higher net margin — 96.3% vs 31.6%, a 64.7% gap on every dollar of revenue. Over the past eight quarters, PROSPERITY BANCSHARES INC's revenue compounded faster (19.2% CAGR vs 17.5%).
Acadia Pharmaceuticals Inc. is a biopharmaceutical company headquartered in Del Mar, San Diego, California.
Prosperity Bancshares, Inc. is a bank holding company headquartered in Houston, Texas with operations in Texas and central Oklahoma. As of December 31, 2019, the company operated 285 branches: 65 in the Houston area, including The Woodlands, Texas; 30 in South Texas, including Corpus Christi, Texas and Victoria, Texas; 75 in the Dallas–Fort Worth metroplex; 22 in East Texas; 29 in Central Texas, including Austin, Texas and San Antonio; 34 in West Texas, including Lubbock, Texas, Midland–Odess...
ACAD vs PB — Head-to-Head
Income Statement — Q4 FY2025 vs Q1 FY2026
| Metric | | |
|---|---|---|
| Revenue | $284.0M | $367.6M |
| Net Profit | $273.6M | $116.3M |
| Gross Margin | 90.8% | — |
| Operating Margin | 6.1% | — |
| Net Margin | 96.3% | 31.6% |
| Revenue YoY | 9.4% | — |
| Net Profit YoY | 90.3% | -10.7% |
| EPS (diluted) | $1.61 | $1.16 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q1 26 | — | $367.6M | ||
| Q4 25 | $284.0M | $275.0M | ||
| Q3 25 | $278.6M | $273.4M | ||
| Q2 25 | $264.6M | $267.7M | ||
| Q1 25 | $244.3M | $265.4M | ||
| Q4 24 | $259.6M | $267.8M | ||
| Q3 24 | $250.4M | $261.7M | ||
| Q2 24 | $242.0M | $258.8M |
| Q1 26 | — | $116.3M | ||
| Q4 25 | $273.6M | $139.9M | ||
| Q3 25 | $71.8M | $137.6M | ||
| Q2 25 | $26.7M | $135.2M | ||
| Q1 25 | $19.0M | $130.2M | ||
| Q4 24 | $143.7M | $130.1M | ||
| Q3 24 | $32.8M | $127.3M | ||
| Q2 24 | $33.4M | $111.6M |
| Q1 26 | — | — | ||
| Q4 25 | 90.8% | — | ||
| Q3 25 | 92.2% | — | ||
| Q2 25 | 92.2% | — | ||
| Q1 25 | 91.7% | — | ||
| Q4 24 | 91.6% | — | ||
| Q3 24 | 92.5% | — | ||
| Q2 24 | 92.5% | — |
| Q1 26 | — | — | ||
| Q4 25 | 6.1% | 65.1% | ||
| Q3 25 | 12.8% | 64.4% | ||
| Q2 25 | 12.2% | 64.3% | ||
| Q1 25 | 7.9% | 62.7% | ||
| Q4 24 | 59.1% | 62.0% | ||
| Q3 24 | 12.6% | 62.1% | ||
| Q2 24 | 12.6% | 55.2% |
| Q1 26 | — | 31.6% | ||
| Q4 25 | 96.3% | 50.9% | ||
| Q3 25 | 25.8% | 50.3% | ||
| Q2 25 | 10.1% | 50.5% | ||
| Q1 25 | 7.8% | 49.1% | ||
| Q4 24 | 55.4% | 48.6% | ||
| Q3 24 | 13.1% | 48.6% | ||
| Q2 24 | 13.8% | 43.1% |
| Q1 26 | — | $1.16 | ||
| Q4 25 | $1.61 | $1.48 | ||
| Q3 25 | $0.42 | $1.45 | ||
| Q2 25 | $0.16 | $1.42 | ||
| Q1 25 | $0.11 | $1.37 | ||
| Q4 24 | $0.86 | $1.36 | ||
| Q3 24 | $0.20 | $1.34 | ||
| Q2 24 | $0.20 | $1.17 |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $177.7M | — |
| Total DebtLower is stronger | — | — |
| Stockholders' EquityBook value | $1.2B | $8.2B |
| Total Assets | $1.6B | $43.6B |
| Debt / EquityLower = less leverage | — | — |
8-quarter trend — quarters aligned by calendar period.
| Q1 26 | — | — | ||
| Q4 25 | $177.7M | — | ||
| Q3 25 | $258.0M | — | ||
| Q2 25 | $253.6M | — | ||
| Q1 25 | $217.7M | — | ||
| Q4 24 | $319.6M | — | ||
| Q3 24 | $155.1M | — | ||
| Q2 24 | $177.1M | — |
| Q1 26 | — | $8.2B | ||
| Q4 25 | $1.2B | $7.6B | ||
| Q3 25 | $917.3M | $7.7B | ||
| Q2 25 | $822.4M | $7.6B | ||
| Q1 25 | $765.2M | $7.5B | ||
| Q4 24 | $732.8M | $7.4B | ||
| Q3 24 | $577.2M | $7.4B | ||
| Q2 24 | $516.7M | $7.3B |
| Q1 26 | — | $43.6B | ||
| Q4 25 | $1.6B | $38.5B | ||
| Q3 25 | $1.3B | $38.3B | ||
| Q2 25 | $1.2B | $38.4B | ||
| Q1 25 | $1.1B | $38.8B | ||
| Q4 24 | $1.2B | $39.6B | ||
| Q3 24 | $976.9M | $40.1B | ||
| Q2 24 | $914.1M | $39.8B |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | $-48.7M | — |
| Free Cash FlowOCF − Capex | — | — |
| FCF MarginFCF / Revenue | — | — |
| Capex IntensityCapex / Revenue | — | — |
| Cash ConversionOCF / Net Profit | -0.18× | — |
| TTM Free Cash FlowTrailing 4 quarters | — | — |
8-quarter trend — quarters aligned by calendar period.
| Q1 26 | — | — | ||
| Q4 25 | $-48.7M | $78.3M | ||
| Q3 25 | $74.3M | $194.8M | ||
| Q2 25 | $64.0M | $98.2M | ||
| Q1 25 | $20.3M | $178.2M | ||
| Q4 24 | $40.4M | $-205.8M | ||
| Q3 24 | $63.2M | $274.6M | ||
| Q2 24 | $25.0M | $216.5M |
| Q1 26 | — | — | ||
| Q4 25 | — | $68.5M | ||
| Q3 25 | $73.9M | $185.7M | ||
| Q2 25 | — | $91.8M | ||
| Q1 25 | — | $171.1M | ||
| Q4 24 | — | $-210.7M | ||
| Q3 24 | $63.2M | $270.2M | ||
| Q2 24 | — | $211.8M |
| Q1 26 | — | — | ||
| Q4 25 | — | 24.9% | ||
| Q3 25 | 26.5% | 67.9% | ||
| Q2 25 | — | 34.3% | ||
| Q1 25 | — | 64.5% | ||
| Q4 24 | — | -78.7% | ||
| Q3 24 | 25.2% | 103.3% | ||
| Q2 24 | — | 81.8% |
| Q1 26 | — | — | ||
| Q4 25 | — | 3.6% | ||
| Q3 25 | 0.1% | 3.3% | ||
| Q2 25 | — | 2.4% | ||
| Q1 25 | — | 2.7% | ||
| Q4 24 | — | 1.8% | ||
| Q3 24 | 0.0% | 1.7% | ||
| Q2 24 | — | 1.8% |
| Q1 26 | — | — | ||
| Q4 25 | -0.18× | 0.56× | ||
| Q3 25 | 1.03× | 1.42× | ||
| Q2 25 | 2.40× | 0.73× | ||
| Q1 25 | 1.07× | 1.37× | ||
| Q4 24 | 0.28× | -1.58× | ||
| Q3 24 | 1.93× | 2.16× | ||
| Q2 24 | 0.75× | 1.94× |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
Revenue Breakdown by Segment
ACAD
| Nuplazid | $174.4M | 61% |
| Daybue | $109.6M | 39% |
PB
| Net Interest Income | $321.1M | 87% |
| Noninterest Income | $46.5M | 13% |
