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Side-by-side financial comparison of ACADIA PHARMACEUTICALS INC (ACAD) and Wheels Up Experience Inc. (UP). Click either name above to swap in a different company.
ACADIA PHARMACEUTICALS INC is the larger business by last-quarter revenue ($284.0M vs $183.8M, roughly 1.5× Wheels Up Experience Inc.). ACADIA PHARMACEUTICALS INC runs the higher net margin — 96.3% vs -15.7%, a 112.0% gap on every dollar of revenue. On growth, ACADIA PHARMACEUTICALS INC posted the faster year-over-year revenue change (9.4% vs -10.2%). Over the past eight quarters, ACADIA PHARMACEUTICALS INC's revenue compounded faster (17.5% CAGR vs -3.4%).
Acadia Pharmaceuticals Inc. is a biopharmaceutical company headquartered in Del Mar, San Diego, California.
Wheels Up is a provider of "on demand" private aviation in the United States and one of the largest private aviation companies in the world. It was founded in 2013 by Kenny Dichter, using a membership/on-demand business model. Wheels Up members can book private aircraft from the company fleet and third-party operators using a mobile application.
ACAD vs UP — Head-to-Head
Income Statement — Q4 FY2025 vs Q4 FY2025
| Metric | | |
|---|---|---|
| Revenue | $284.0M | $183.8M |
| Net Profit | $273.6M | $-28.9M |
| Gross Margin | 90.8% | 14.3% |
| Operating Margin | 6.1% | -0.9% |
| Net Margin | 96.3% | -15.7% |
| Revenue YoY | 9.4% | -10.2% |
| Net Profit YoY | 90.3% | 67.0% |
| EPS (diluted) | $1.61 | $-0.04 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q4 25 | $284.0M | $183.8M | ||
| Q3 25 | $278.6M | $185.5M | ||
| Q2 25 | $264.6M | $189.6M | ||
| Q1 25 | $244.3M | $177.5M | ||
| Q4 24 | $259.6M | $204.8M | ||
| Q3 24 | $250.4M | $193.9M | ||
| Q2 24 | $242.0M | $196.3M | ||
| Q1 24 | $205.8M | $197.1M |
| Q4 25 | $273.6M | $-28.9M | ||
| Q3 25 | $71.8M | $-83.7M | ||
| Q2 25 | $26.7M | $-82.3M | ||
| Q1 25 | $19.0M | $-99.3M | ||
| Q4 24 | $143.7M | $-87.5M | ||
| Q3 24 | $32.8M | $-57.7M | ||
| Q2 24 | $33.4M | $-97.0M | ||
| Q1 24 | $16.6M | $-97.4M |
| Q4 25 | 90.8% | 14.3% | ||
| Q3 25 | 92.2% | 6.8% | ||
| Q2 25 | 92.2% | 8.3% | ||
| Q1 25 | 91.7% | 10.8% | ||
| Q4 24 | 91.6% | 13.9% | ||
| Q3 24 | 92.5% | 13.9% | ||
| Q2 24 | 92.5% | 2.3% | ||
| Q1 24 | 88.8% | -0.6% |
| Q4 25 | 6.1% | -0.9% | ||
| Q3 25 | 12.8% | -33.1% | ||
| Q2 25 | 12.2% | -31.4% | ||
| Q1 25 | 7.9% | -45.5% | ||
| Q4 24 | 59.1% | -26.0% | ||
| Q3 24 | 12.6% | -21.6% | ||
| Q2 24 | 12.6% | -40.3% | ||
| Q1 24 | 7.4% | -42.9% |
| Q4 25 | 96.3% | -15.7% | ||
| Q3 25 | 25.8% | -45.1% | ||
| Q2 25 | 10.1% | -43.4% | ||
| Q1 25 | 7.8% | -55.9% | ||
| Q4 24 | 55.4% | -42.7% | ||
| Q3 24 | 13.1% | -29.8% | ||
| Q2 24 | 13.8% | -49.4% | ||
| Q1 24 | 8.0% | -49.4% |
| Q4 25 | $1.61 | $-0.04 | ||
| Q3 25 | $0.42 | $-0.12 | ||
| Q2 25 | $0.16 | $-0.12 | ||
| Q1 25 | $0.11 | $-0.14 | ||
| Q4 24 | $0.86 | $-0.13 | ||
| Q3 24 | $0.20 | $-0.08 | ||
| Q2 24 | $0.20 | $-0.14 | ||
| Q1 24 | $0.10 | $-0.14 |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $177.7M | $133.9M |
| Total DebtLower is stronger | — | $671.3M |
| Stockholders' EquityBook value | $1.2B | $-392.1M |
| Total Assets | $1.6B | $968.8M |
| Debt / EquityLower = less leverage | — | — |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $177.7M | $133.9M | ||
| Q3 25 | $258.0M | $125.3M | ||
| Q2 25 | $253.6M | $107.0M | ||
| Q1 25 | $217.7M | $171.8M | ||
| Q4 24 | $319.6M | $216.4M | ||
| Q3 24 | $155.1M | $115.9M | ||
| Q2 24 | $177.1M | $141.5M | ||
| Q1 24 | $204.7M | $180.9M |
| Q4 25 | — | $671.3M | ||
| Q3 25 | — | $766.5M | ||
| Q2 25 | — | $770.5M | ||
| Q1 25 | — | $765.8M | ||
| Q4 24 | — | $761.3M | ||
| Q3 24 | — | $596.9M | ||
| Q2 24 | — | $597.4M | ||
| Q1 24 | — | $603.2M |
| Q4 25 | $1.2B | $-392.1M | ||
| Q3 25 | $917.3M | $-374.5M | ||
| Q2 25 | $822.4M | $-347.8M | ||
| Q1 25 | $765.2M | $-288.1M | ||
| Q4 24 | $732.8M | $-202.1M | ||
| Q3 24 | $577.2M | $-117.7M | ||
| Q2 24 | $516.7M | $-72.2M | ||
| Q1 24 | $464.0M | $936.0K |
| Q4 25 | $1.6B | $968.8M | ||
| Q3 25 | $1.3B | $973.0M | ||
| Q2 25 | $1.2B | $1.0B | ||
| Q1 25 | $1.1B | $1.1B | ||
| Q4 24 | $1.2B | $1.2B | ||
| Q3 24 | $976.9M | $1.0B | ||
| Q2 24 | $914.1M | $1.1B | ||
| Q1 24 | $855.1M | $1.2B |
| Q4 25 | — | — | ||
| Q3 25 | — | — | ||
| Q2 25 | — | — | ||
| Q1 25 | — | — | ||
| Q4 24 | — | — | ||
| Q3 24 | — | — | ||
| Q2 24 | — | — | ||
| Q1 24 | — | 644.43× |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | $-48.7M | $-18.4M |
| Free Cash FlowOCF − Capex | — | $-58.3M |
| FCF MarginFCF / Revenue | — | -31.7% |
| Capex IntensityCapex / Revenue | — | 21.7% |
| Cash ConversionOCF / Net Profit | -0.18× | — |
| TTM Free Cash FlowTrailing 4 quarters | — | $-259.9M |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $-48.7M | $-18.4M | ||
| Q3 25 | $74.3M | $-37.1M | ||
| Q2 25 | $64.0M | $-62.9M | ||
| Q1 25 | $20.3M | $-47.9M | ||
| Q4 24 | $40.4M | $37.9M | ||
| Q3 24 | $63.2M | $-16.9M | ||
| Q2 24 | $25.0M | $-25.2M | ||
| Q1 24 | $29.1M | $-73.8M |
| Q4 25 | — | $-58.3M | ||
| Q3 25 | $73.9M | $-60.4M | ||
| Q2 25 | — | $-78.6M | ||
| Q1 25 | — | $-62.6M | ||
| Q4 24 | — | $-70.2M | ||
| Q3 24 | $63.2M | $-21.9M | ||
| Q2 24 | — | $-30.8M | ||
| Q1 24 | — | $-77.8M |
| Q4 25 | — | -31.7% | ||
| Q3 25 | 26.5% | -32.6% | ||
| Q2 25 | — | -41.5% | ||
| Q1 25 | — | -35.3% | ||
| Q4 24 | — | -34.3% | ||
| Q3 24 | 25.2% | -11.3% | ||
| Q2 24 | — | -15.7% | ||
| Q1 24 | — | -39.5% |
| Q4 25 | — | 21.7% | ||
| Q3 25 | 0.1% | 12.5% | ||
| Q2 25 | — | 8.3% | ||
| Q1 25 | — | 8.3% | ||
| Q4 24 | — | 52.8% | ||
| Q3 24 | 0.0% | 2.6% | ||
| Q2 24 | — | 2.9% | ||
| Q1 24 | — | 2.0% |
| Q4 25 | -0.18× | — | ||
| Q3 25 | 1.03× | — | ||
| Q2 25 | 2.40× | — | ||
| Q1 25 | 1.07× | — | ||
| Q4 24 | 0.28× | — | ||
| Q3 24 | 1.93× | — | ||
| Q2 24 | 0.75× | — | ||
| Q1 24 | 1.76× | — |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
Revenue Breakdown by Segment
ACAD
| Nuplazid | $174.4M | 61% |
| Daybue | $109.6M | 39% |
UP
Segment breakdown not available.
