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Side-by-side financial comparison of Adaptive Biotechnologies Corp (ADPT) and Esquire Financial Holdings, Inc. (ESQ). Click either name above to swap in a different company.

Adaptive Biotechnologies Corp is the larger business by last-quarter revenue ($71.7M vs $40.5M, roughly 1.8× Esquire Financial Holdings, Inc.). Esquire Financial Holdings, Inc. runs the higher net margin — 30.2% vs -18.9%, a 49.1% gap on every dollar of revenue. Over the past eight quarters, Adaptive Biotechnologies Corp's revenue compounded faster (30.8% CAGR vs 15.0%).

ExpreS2ion Biotechnologies is a Danish biotechnology company specialised in the development of new vaccines and immunotherapy products based in Hørsholm, Denmark and listed on the Nasdaq First North Growth Market Sweden.

Esquire Financial Holdings, Inc. is a U.S.-headquartered bank holding company that provides comprehensive commercial and consumer banking products and services. Its core offerings include deposit accounts, business loans, mortgage services, and wealth management solutions, primarily serving small to medium enterprises, legal industry professionals, and local retail clients.

ADPT vs ESQ — Head-to-Head

Bigger by revenue
ADPT
ADPT
1.8× larger
ADPT
$71.7M
$40.5M
ESQ
Higher net margin
ESQ
ESQ
49.1% more per $
ESQ
30.2%
-18.9%
ADPT
Faster 2-yr revenue CAGR
ADPT
ADPT
Annualised
ADPT
30.8%
15.0%
ESQ

Income Statement — Q4 FY2025 vs Q1 FY2026

Metric
ADPT
ADPT
ESQ
ESQ
Revenue
$71.7M
$40.5M
Net Profit
$-13.6M
$12.2M
Gross Margin
74.6%
Operating Margin
-17.8%
Net Margin
-18.9%
30.2%
Revenue YoY
51.0%
Net Profit YoY
59.7%
7.0%
EPS (diluted)
$-0.08
$1.40

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
ADPT
ADPT
ESQ
ESQ
Q1 26
$40.5M
Q4 25
$71.7M
$39.4M
Q3 25
$94.0M
$37.6M
Q2 25
$58.9M
$35.8M
Q1 25
$52.4M
$33.8M
Q4 24
$47.5M
$33.1M
Q3 24
$46.4M
$31.9M
Q2 24
$43.2M
$30.6M
Net Profit
ADPT
ADPT
ESQ
ESQ
Q1 26
$12.2M
Q4 25
$-13.6M
$13.5M
Q3 25
$9.5M
$14.1M
Q2 25
$-25.6M
$11.9M
Q1 25
$-29.9M
$11.4M
Q4 24
$-33.7M
$11.8M
Q3 24
$-32.1M
$11.4M
Q2 24
$-46.2M
$10.5M
Gross Margin
ADPT
ADPT
ESQ
ESQ
Q1 26
Q4 25
74.6%
Q3 25
80.7%
Q2 25
69.4%
Q1 25
67.6%
Q4 24
62.0%
Q3 24
64.1%
Q2 24
55.3%
Operating Margin
ADPT
ADPT
ESQ
ESQ
Q1 26
Q4 25
-17.8%
44.3%
Q3 25
10.9%
46.5%
Q2 25
-42.5%
42.5%
Q1 25
-56.4%
45.9%
Q4 24
-71.3%
47.4%
Q3 24
-70.3%
48.8%
Q2 24
-109.6%
46.9%
Net Margin
ADPT
ADPT
ESQ
ESQ
Q1 26
30.2%
Q4 25
-18.9%
34.2%
Q3 25
10.2%
37.4%
Q2 25
-43.5%
33.2%
Q1 25
-56.9%
33.8%
Q4 24
-71.0%
35.6%
Q3 24
-69.1%
35.6%
Q2 24
-107.0%
34.3%
EPS (diluted)
ADPT
ADPT
ESQ
ESQ
Q1 26
$1.40
Q4 25
$-0.08
$1.54
Q3 25
$0.06
$1.62
Q2 25
$-0.17
$1.38
Q1 25
$-0.20
$1.33
Q4 24
$-0.22
$1.35
Q3 24
$-0.22
$1.34
Q2 24
$-0.31
$1.25

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
ADPT
ADPT
ESQ
ESQ
Cash + ST InvestmentsLiquidity on hand
$70.5M
$222.2M
Total DebtLower is stronger
Stockholders' EquityBook value
$218.8M
$301.3M
Total Assets
$512.7M
$2.4B
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
ADPT
ADPT
ESQ
ESQ
Q1 26
$222.2M
Q4 25
$70.5M
$235.9M
Q3 25
$55.0M
$240.8M
Q2 25
$43.2M
$163.0M
Q1 25
$50.6M
$173.0M
Q4 24
$47.9M
$126.3M
Q3 24
$38.1M
$147.7M
Q2 24
$59.8M
$152.7M
Stockholders' Equity
ADPT
ADPT
ESQ
ESQ
Q1 26
$301.3M
Q4 25
$218.8M
$289.6M
Q3 25
$204.4M
$279.2M
Q2 25
$179.7M
$263.6M
Q1 25
$190.4M
$250.7M
Q4 24
$202.7M
$237.1M
Q3 24
$223.8M
$232.6M
Q2 24
$241.6M
$217.4M
Total Assets
ADPT
ADPT
ESQ
ESQ
Q1 26
$2.4B
Q4 25
$512.7M
$2.4B
Q3 25
$490.6M
$2.2B
Q2 25
$496.6M
$2.1B
Q1 25
$510.9M
$2.0B
Q4 24
$539.4M
$1.9B
Q3 24
$558.5M
$1.8B
Q2 24
$584.9M
$1.7B

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
ADPT
ADPT
ESQ
ESQ
Operating Cash FlowLast quarter
$2.1M
Free Cash FlowOCF − Capex
$1.4M
FCF MarginFCF / Revenue
2.0%
Capex IntensityCapex / Revenue
0.9%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$-48.9M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
ADPT
ADPT
ESQ
ESQ
Q1 26
Q4 25
$2.1M
$59.8M
Q3 25
$-7.1M
$16.8M
Q2 25
$-12.4M
$10.5M
Q1 25
$-28.5M
$15.8M
Q4 24
$-12.5M
$42.2M
Q3 24
$-27.1M
$10.5M
Q2 24
$-17.3M
$7.2M
Free Cash Flow
ADPT
ADPT
ESQ
ESQ
Q1 26
Q4 25
$1.4M
$56.7M
Q3 25
$-7.5M
$16.2M
Q2 25
$-13.1M
$9.3M
Q1 25
$-29.7M
$14.7M
Q4 24
$-12.6M
$41.5M
Q3 24
$-27.4M
$10.5M
Q2 24
$-19.0M
$6.9M
FCF Margin
ADPT
ADPT
ESQ
ESQ
Q1 26
Q4 25
2.0%
143.9%
Q3 25
-8.0%
43.2%
Q2 25
-22.2%
26.0%
Q1 25
-56.7%
43.4%
Q4 24
-26.5%
125.5%
Q3 24
-59.0%
32.8%
Q2 24
-44.1%
22.5%
Capex Intensity
ADPT
ADPT
ESQ
ESQ
Q1 26
Q4 25
0.9%
8.0%
Q3 25
0.4%
1.3%
Q2 25
1.1%
3.2%
Q1 25
2.4%
3.4%
Q4 24
0.2%
2.2%
Q3 24
0.7%
0.2%
Q2 24
4.0%
1.1%
Cash Conversion
ADPT
ADPT
ESQ
ESQ
Q1 26
Q4 25
4.44×
Q3 25
-0.75×
1.19×
Q2 25
0.88×
Q1 25
1.39×
Q4 24
3.59×
Q3 24
0.93×
Q2 24
0.69×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

ADPT
ADPT

Mrd Business Segment$61.9M86%
Immune Medicine Business$9.8M14%
Immune Medicine Service Revenue$100.0K0%

ESQ
ESQ

Net Interest Income$34.0M84%
Noninterest Income$6.5M16%

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