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Side-by-side financial comparison of AGENUS INC (AGEN) and HomeTrust Bancshares, Inc. (HTB). Click either name above to swap in a different company.

HomeTrust Bancshares, Inc. is the larger business by last-quarter revenue ($53.6M vs $34.2M, roughly 1.6× AGENUS INC). On growth, AGENUS INC posted the faster year-over-year revenue change (27.5% vs 3.7%). Over the past eight quarters, AGENUS INC's revenue compounded faster (10.5% CAGR vs 3.5%).

Agenus Inc. is a Lexington, Massachusetts-based biotechnology company focused on immunotherapy including immuno-oncology, a field that uses the immune system to control or cure cancer. The company is developing checkpoint modulators (CPMs), patient-specific anti-cancer vaccines, and adjuvants designed for use with various vaccines. CPM development is a particularly fast-moving field, since early products have produced unprecedented clinical benefits for patients.

HomeTrust Bancshares Inc. is an Asheville, North Carolina–based bank holding company with $4.3 billion in assets and 33 branches in North and South Carolina, Georgia and Tennessee. It is the parent of seven community banks—HomeTrust Bank, Tryon Federal Bank, Shelby Savings Bank, Home Savings Bank, Industrial Federal Bank, Cherryville Federal Bank and Rutherford County Bank.

AGEN vs HTB — Head-to-Head

Bigger by revenue
HTB
HTB
1.6× larger
HTB
$53.6M
$34.2M
AGEN
Growing faster (revenue YoY)
AGEN
AGEN
+23.8% gap
AGEN
27.5%
3.7%
HTB
Faster 2-yr revenue CAGR
AGEN
AGEN
Annualised
AGEN
10.5%
3.5%
HTB

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
AGEN
AGEN
HTB
HTB
Revenue
$34.2M
$53.6M
Net Profit
$-10.6M
Gross Margin
Operating Margin
42.1%
37.0%
Net Margin
-31.0%
Revenue YoY
27.5%
3.7%
Net Profit YoY
77.3%
EPS (diluted)
$0.09
$0.93

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
AGEN
AGEN
HTB
HTB
Q4 25
$34.2M
$53.6M
Q3 25
$30.2M
$54.1M
Q2 25
$25.7M
$54.4M
Q1 25
$24.1M
$50.9M
Q4 24
$26.8M
$51.7M
Q3 24
$25.1M
$50.6M
Q2 24
$23.5M
$50.6M
Q1 24
$28.0M
$50.0M
Net Profit
AGEN
AGEN
HTB
HTB
Q4 25
$-10.6M
Q3 25
$63.9M
$16.5M
Q2 25
$-30.0M
$17.2M
Q1 25
$-26.4M
$14.5M
Q4 24
$-46.8M
Q3 24
$-67.2M
$13.1M
Q2 24
$-54.8M
$12.4M
Q1 24
$-63.5M
$15.1M
Gross Margin
AGEN
AGEN
HTB
HTB
Q4 25
Q3 25
97.9%
Q2 25
99.1%
Q1 25
99.4%
Q4 24
99.6%
Q3 24
99.4%
Q2 24
99.5%
Q1 24
99.6%
Operating Margin
AGEN
AGEN
HTB
HTB
Q4 25
42.1%
37.0%
Q3 25
-15.0%
38.5%
Q2 25
-65.0%
40.1%
Q1 25
-55.3%
36.2%
Q4 24
-96.5%
35.4%
Q3 24
-125.5%
33.2%
Q2 24
-128.4%
31.3%
Q1 24
-117.4%
38.0%
Net Margin
AGEN
AGEN
HTB
HTB
Q4 25
-31.0%
Q3 25
211.4%
30.5%
Q2 25
-116.8%
31.6%
Q1 25
-109.6%
28.5%
Q4 24
-174.4%
Q3 24
-267.7%
25.9%
Q2 24
-233.1%
24.6%
Q1 24
-226.6%
30.1%
EPS (diluted)
AGEN
AGEN
HTB
HTB
Q4 25
$0.09
$0.93
Q3 25
$1.94
$0.95
Q2 25
$-1.00
$1.00
Q1 25
$-1.03
$0.84
Q4 24
$-1.95
$0.83
Q3 24
$-3.08
$0.76
Q2 24
$-2.52
$0.73
Q1 24
$-3.04
$0.88

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
AGEN
AGEN
HTB
HTB
Cash + ST InvestmentsLiquidity on hand
$3.0M
$324.7M
Total DebtLower is stronger
$44.7M
Stockholders' EquityBook value
$-271.1M
$600.7M
Total Assets
$226.8M
$4.5B
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
AGEN
AGEN
HTB
HTB
Q4 25
$3.0M
$324.7M
Q3 25
$3.5M
$315.8M
Q2 25
$9.5M
$297.2M
Q1 25
$18.5M
$299.8M
Q4 24
$40.4M
$279.2M
Q3 24
$44.8M
$293.5M
Q2 24
$93.7M
$294.2M
Q1 24
$52.9M
$380.5M
Total Debt
AGEN
AGEN
HTB
HTB
Q4 25
$44.7M
Q3 25
$34.2M
Q2 25
$33.9M
Q1 25
$33.6M
Q4 24
$33.2M
Q3 24
Q2 24
Q1 24
Stockholders' Equity
AGEN
AGEN
HTB
HTB
Q4 25
$-271.1M
$600.7M
Q3 25
$-274.1M
$595.8M
Q2 25
$-354.6M
$579.3M
Q1 25
$-341.8M
$565.4M
Q4 24
$-326.4M
$551.8M
Q3 24
$-292.3M
$540.0M
Q2 24
$-241.3M
$523.6M
Q1 24
$-201.4M
$513.2M
Total Assets
AGEN
AGEN
HTB
HTB
Q4 25
$226.8M
$4.5B
Q3 25
$233.9M
$4.6B
Q2 25
$185.2M
$4.6B
Q1 25
$200.2M
$4.6B
Q4 24
$226.3M
$4.6B
Q3 24
$238.5M
$4.6B
Q2 24
$292.4M
$4.7B
Q1 24
$256.6M
$4.7B

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
AGEN
AGEN
HTB
HTB
Operating Cash FlowLast quarter
$-16.6M
$49.5M
Free Cash FlowOCF − Capex
$45.3M
FCF MarginFCF / Revenue
84.5%
Capex IntensityCapex / Revenue
0.0%
7.8%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$93.8M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
AGEN
AGEN
HTB
HTB
Q4 25
$-16.6M
$49.5M
Q3 25
$-14.7M
$-11.3M
Q2 25
$-20.2M
$-8.8M
Q1 25
$-25.6M
$71.7M
Q4 24
$-28.7M
$45.4M
Q3 24
$-53.3M
$43.8M
Q2 24
$-38.2M
$5.9M
Q1 24
$-38.2M
$-9.0M
Free Cash Flow
AGEN
AGEN
HTB
HTB
Q4 25
$45.3M
Q3 25
$-12.0M
Q2 25
$-20.2M
$-10.2M
Q1 25
$-25.6M
$70.7M
Q4 24
$-28.7M
$42.4M
Q3 24
$-53.3M
$43.1M
Q2 24
$-38.6M
$5.7M
Q1 24
$-38.2M
$-9.6M
FCF Margin
AGEN
AGEN
HTB
HTB
Q4 25
84.5%
Q3 25
-22.2%
Q2 25
-78.7%
-18.7%
Q1 25
-106.5%
138.7%
Q4 24
-107.0%
82.0%
Q3 24
-212.2%
85.1%
Q2 24
-164.4%
11.2%
Q1 24
-136.5%
-19.2%
Capex Intensity
AGEN
AGEN
HTB
HTB
Q4 25
0.0%
7.8%
Q3 25
0.0%
1.4%
Q2 25
0.0%
2.5%
Q1 25
0.0%
2.0%
Q4 24
0.3%
5.9%
Q3 24
0.0%
1.3%
Q2 24
2.0%
0.5%
Q1 24
0.1%
1.1%
Cash Conversion
AGEN
AGEN
HTB
HTB
Q4 25
Q3 25
-0.23×
-0.68×
Q2 25
-0.51×
Q1 25
4.93×
Q4 24
Q3 24
3.34×
Q2 24
0.48×
Q1 24
-0.60×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

AGEN
AGEN

Non Cash Royalty Revenue$31.1M91%
Other$3.2M9%

HTB
HTB

Segment breakdown not available.

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