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Side-by-side financial comparison of AGIOS PHARMACEUTICALS, INC. (AGIO) and GAIA, INC (GAIA). Click either name above to swap in a different company.
GAIA, INC is the larger business by last-quarter revenue ($25.5M vs $20.0M, roughly 1.3× AGIOS PHARMACEUTICALS, INC.). GAIA, INC runs the higher net margin — -0.3% vs -541.1%, a 540.8% gap on every dollar of revenue. On growth, AGIOS PHARMACEUTICALS, INC. posted the faster year-over-year revenue change (86.1% vs 5.8%). GAIA, INC produced more free cash flow last quarter ($76.0K vs $-97.3M). Over the past eight quarters, AGIOS PHARMACEUTICALS, INC.'s revenue compounded faster (56.1% CAGR vs 9.4%).
Agios Pharmaceuticals Inc. is a publicly trading American pharmaceutical company pioneering therapies for genetically defined diseases, with a near-term focus on developing therapies for hemolytic anemias. The company was founded in 2008 by Lewis Cantley, Tak Mak and Craig Thompson. Agios is a Delaware corporation headquartered in Cambridge, Massachusetts. The company tendered an initial public offering in July 2013.
Gaia, Inc. is a publicly traded (NASDAQ:GAIA) American media company founded in 1988 by Jirka Rysavy in Louisville, Colorado. It owns and operates Gaia TV, a subscription video on-demand service consisting of original and licensed alternative media documentaries, including those on wellness, spirituality and conspiracy theories.
AGIO vs GAIA — Head-to-Head
Income Statement — Q4 FY2025 vs Q4 FY2025
| Metric | | |
|---|---|---|
| Revenue | $20.0M | $25.5M |
| Net Profit | $-108.0M | $-75.0K |
| Gross Margin | 90.6% | 87.6% |
| Operating Margin | -608.9% | -2.6% |
| Net Margin | -541.1% | -0.3% |
| Revenue YoY | 86.1% | 5.8% |
| Net Profit YoY | -11.9% | 91.7% |
| EPS (diluted) | $-1.86 | $-0.02 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q4 25 | $20.0M | $25.5M | ||
| Q3 25 | $12.9M | $25.0M | ||
| Q2 25 | $12.5M | $24.6M | ||
| Q1 25 | $8.7M | $23.8M | ||
| Q4 24 | $10.7M | $24.1M | ||
| Q3 24 | $9.0M | $22.0M | ||
| Q2 24 | $8.6M | $21.9M | ||
| Q1 24 | $8.2M | $21.3M |
| Q4 25 | $-108.0M | $-75.0K | ||
| Q3 25 | $-103.4M | $-1.2M | ||
| Q2 25 | $-112.0M | $-2.0M | ||
| Q1 25 | $-89.3M | $-1.2M | ||
| Q4 24 | $-96.5M | $-907.0K | ||
| Q3 24 | $947.9M | $-1.2M | ||
| Q2 24 | $-96.1M | $-2.2M | ||
| Q1 24 | $-81.5M | $-971.0K |
| Q4 25 | 90.6% | 87.6% | ||
| Q3 25 | 87.0% | 86.4% | ||
| Q2 25 | 86.3% | 86.7% | ||
| Q1 25 | 87.6% | 87.7% | ||
| Q4 24 | 88.3% | 88.2% | ||
| Q3 24 | 91.3% | 86.1% | ||
| Q2 24 | 82.6% | 84.5% | ||
| Q1 24 | 92.3% | 85.3% |
| Q4 25 | -608.9% | -2.6% | ||
| Q3 25 | -907.4% | -5.0% | ||
| Q2 25 | -1020.1% | -8.9% | ||
| Q1 25 | -1222.0% | -4.3% | ||
| Q4 24 | -1165.3% | -7.1% | ||
| Q3 24 | -1146.9% | -5.3% | ||
| Q2 24 | -1228.3% | -9.1% | ||
| Q1 24 | -1124.3% | -4.0% |
| Q4 25 | -541.1% | -0.3% | ||
| Q3 25 | -803.1% | -4.6% | ||
| Q2 25 | -899.4% | -8.3% | ||
| Q1 25 | -1023.3% | -5.1% | ||
| Q4 24 | -899.6% | -3.8% | ||
| Q3 24 | 10574.7% | -5.4% | ||
| Q2 24 | -1115.7% | -9.9% | ||
| Q1 24 | -995.8% | -4.6% |
| Q4 25 | $-1.86 | $-0.02 | ||
| Q3 25 | $-1.78 | $-0.05 | ||
| Q2 25 | $-1.93 | $-0.07 | ||
| Q1 25 | $-1.55 | $-0.04 | ||
| Q4 24 | $-1.44 | $-0.03 | ||
| Q3 24 | $16.22 | $-0.05 | ||
| Q2 24 | $-1.69 | $-0.09 | ||
| Q1 24 | $-1.45 | $-0.05 |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $89.1M | $13.5M |
| Total DebtLower is stronger | — | — |
| Stockholders' EquityBook value | $1.2B | $87.9M |
| Total Assets | $1.3B | $154.6M |
| Debt / EquityLower = less leverage | — | — |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $89.1M | $13.5M | ||
| Q3 25 | $92.7M | $14.2M | ||
| Q2 25 | $80.9M | $13.9M | ||
| Q1 25 | $79.0M | $13.1M | ||
| Q4 24 | $76.2M | $5.9M | ||
| Q3 24 | $253.7M | $4.4M | ||
| Q2 24 | $84.5M | $5.5M | ||
| Q1 24 | $118.8M | $8.6M |
| Q4 25 | $1.2B | $87.9M | ||
| Q3 25 | $1.3B | $86.3M | ||
| Q2 25 | $1.4B | $85.7M | ||
| Q1 25 | $1.5B | $87.0M | ||
| Q4 24 | $1.5B | $80.7M | ||
| Q3 24 | $1.6B | $81.2M | ||
| Q2 24 | $660.5M | $82.1M | ||
| Q1 24 | $743.9M | $84.8M |
| Q4 25 | $1.3B | $154.6M | ||
| Q3 25 | $1.4B | $151.1M | ||
| Q2 25 | $1.5B | $147.0M | ||
| Q1 25 | $1.6B | $148.5M | ||
| Q4 24 | $1.7B | $141.2M | ||
| Q3 24 | $1.8B | $139.6M | ||
| Q2 24 | $773.1M | $142.1M | ||
| Q1 24 | $849.7M | $133.8M |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | $-96.2M | $1.8M |
| Free Cash FlowOCF − Capex | $-97.3M | $76.0K |
| FCF MarginFCF / Revenue | -487.5% | 0.3% |
| Capex IntensityCapex / Revenue | 5.6% | 6.6% |
| Cash ConversionOCF / Net Profit | — | — |
| TTM Free Cash FlowTrailing 4 quarters | $-377.3M | $-377.0K |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $-96.2M | $1.8M | ||
| Q3 25 | $-88.2M | $326.0K | ||
| Q2 25 | $-77.1M | $2.3M | ||
| Q1 25 | $-111.5M | $1.3M | ||
| Q4 24 | $-133.2M | $2.7M | ||
| Q3 24 | $-84.2M | $409.0K | ||
| Q2 24 | $-72.6M | $-2.1M | ||
| Q1 24 | $-99.9M | $5.9M |
| Q4 25 | $-97.3M | $76.0K | ||
| Q3 25 | $-89.7M | $-1.6M | ||
| Q2 25 | $-78.0M | $880.0K | ||
| Q1 25 | $-112.3M | $268.0K | ||
| Q4 24 | $-134.1M | $1.6M | ||
| Q3 24 | $-84.6M | $-952.0K | ||
| Q2 24 | $-72.7M | $-3.5M | ||
| Q1 24 | $-100.0M | $4.9M |
| Q4 25 | -487.5% | 0.3% | ||
| Q3 25 | -696.5% | -6.4% | ||
| Q2 25 | -626.2% | 3.6% | ||
| Q1 25 | -1286.4% | 1.1% | ||
| Q4 24 | -1250.1% | 6.5% | ||
| Q3 24 | -944.2% | -4.3% | ||
| Q2 24 | -844.4% | -16.1% | ||
| Q1 24 | -1221.2% | 22.8% |
| Q4 25 | 5.6% | 6.6% | ||
| Q3 25 | 12.1% | 7.7% | ||
| Q2 25 | 7.0% | 5.7% | ||
| Q1 25 | 8.8% | 4.3% | ||
| Q4 24 | 9.0% | 4.6% | ||
| Q3 24 | 4.7% | 6.2% | ||
| Q2 24 | 1.8% | 6.6% | ||
| Q1 24 | 1.7% | 5.0% |
| Q4 25 | — | — | ||
| Q3 25 | — | — | ||
| Q2 25 | — | — | ||
| Q1 25 | — | — | ||
| Q4 24 | — | — | ||
| Q3 24 | -0.09× | — | ||
| Q2 24 | — | — | ||
| Q1 24 | — | — |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
Revenue Breakdown by Segment
AGIO
Segment breakdown not available.
GAIA
| US | $16.7M | 65% |
| Non Us | $8.8M | 35% |
