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Side-by-side financial comparison of AGIOS PHARMACEUTICALS, INC. (AGIO) and HARTE HANKS INC (HHS). Click either name above to swap in a different company.

HARTE HANKS INC is the larger business by last-quarter revenue ($39.9M vs $20.0M, roughly 2.0× AGIOS PHARMACEUTICALS, INC.). HARTE HANKS INC runs the higher net margin — 5.5% vs -541.1%, a 546.6% gap on every dollar of revenue. On growth, AGIOS PHARMACEUTICALS, INC. posted the faster year-over-year revenue change (86.1% vs -15.4%). HARTE HANKS INC produced more free cash flow last quarter ($-686.0K vs $-97.3M). Over the past eight quarters, AGIOS PHARMACEUTICALS, INC.'s revenue compounded faster (56.1% CAGR vs -6.4%).

Agios Pharmaceuticals Inc. is a publicly trading American pharmaceutical company pioneering therapies for genetically defined diseases, with a near-term focus on developing therapies for hemolytic anemias. The company was founded in 2008 by Lewis Cantley, Tak Mak and Craig Thompson. Agios is a Delaware corporation headquartered in Cambridge, Massachusetts. The company tendered an initial public offering in July 2013.

Harte Hanks is a global marketing services company headquartered in Boston, Massachusetts. Harte Hanks services include analytics, strategy, marketing technology, creative services, digital marketing, customer care, direct mail, logistics, and fulfillment.

AGIO vs HHS — Head-to-Head

Bigger by revenue
HHS
HHS
2.0× larger
HHS
$39.9M
$20.0M
AGIO
Growing faster (revenue YoY)
AGIO
AGIO
+101.5% gap
AGIO
86.1%
-15.4%
HHS
Higher net margin
HHS
HHS
546.6% more per $
HHS
5.5%
-541.1%
AGIO
More free cash flow
HHS
HHS
$96.6M more FCF
HHS
$-686.0K
$-97.3M
AGIO
Faster 2-yr revenue CAGR
AGIO
AGIO
Annualised
AGIO
56.1%
-6.4%
HHS

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
AGIO
AGIO
HHS
HHS
Revenue
$20.0M
$39.9M
Net Profit
$-108.0M
$2.2M
Gross Margin
90.6%
Operating Margin
-608.9%
-0.3%
Net Margin
-541.1%
5.5%
Revenue YoY
86.1%
-15.4%
Net Profit YoY
-11.9%
EPS (diluted)
$-1.86
$0.30

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
AGIO
AGIO
HHS
HHS
Q4 25
$20.0M
$39.9M
Q3 25
$12.9M
$39.5M
Q2 25
$12.5M
$38.6M
Q1 25
$8.7M
$41.6M
Q4 24
$10.7M
$47.1M
Q3 24
$9.0M
$47.6M
Q2 24
$8.6M
$45.0M
Q1 24
$8.2M
$45.4M
Net Profit
AGIO
AGIO
HHS
HHS
Q4 25
$-108.0M
$2.2M
Q3 25
$-103.4M
$-2.3M
Q2 25
$-112.0M
$-335.0K
Q1 25
$-89.3M
$-392.0K
Q4 24
$-96.5M
Q3 24
$947.9M
$142.0K
Q2 24
$-96.1M
$-27.8M
Q1 24
$-81.5M
$-171.0K
Gross Margin
AGIO
AGIO
HHS
HHS
Q4 25
90.6%
Q3 25
87.0%
Q2 25
86.3%
Q1 25
87.6%
Q4 24
88.3%
Q3 24
91.3%
Q2 24
82.6%
Q1 24
92.3%
Operating Margin
AGIO
AGIO
HHS
HHS
Q4 25
-608.9%
-0.3%
Q3 25
-907.4%
1.3%
Q2 25
-1020.1%
0.1%
Q1 25
-1222.0%
-0.1%
Q4 24
-1165.3%
-3.3%
Q3 24
-1146.9%
4.0%
Q2 24
-1228.3%
3.0%
Q1 24
-1124.3%
0.8%
Net Margin
AGIO
AGIO
HHS
HHS
Q4 25
-541.1%
5.5%
Q3 25
-803.1%
-5.8%
Q2 25
-899.4%
-0.9%
Q1 25
-1023.3%
-0.9%
Q4 24
-899.6%
Q3 24
10574.7%
0.3%
Q2 24
-1115.7%
-61.8%
Q1 24
-995.8%
-0.4%
EPS (diluted)
AGIO
AGIO
HHS
HHS
Q4 25
$-1.86
$0.30
Q3 25
$-1.78
$-0.31
Q2 25
$-1.93
$-0.05
Q1 25
$-1.55
$-0.05
Q4 24
$-1.44
$-0.31
Q3 24
$16.22
$0.02
Q2 24
$-1.69
$-3.84
Q1 24
$-1.45
$-0.02

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
AGIO
AGIO
HHS
HHS
Cash + ST InvestmentsLiquidity on hand
$89.1M
$5.6M
Total DebtLower is stronger
Stockholders' EquityBook value
$1.2B
$20.5M
Total Assets
$1.3B
$91.8M
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
AGIO
AGIO
HHS
HHS
Q4 25
$89.1M
$5.6M
Q3 25
$92.7M
$6.5M
Q2 25
$80.9M
$4.8M
Q1 25
$79.0M
$9.0M
Q4 24
$76.2M
$9.8M
Q3 24
$253.7M
$5.9M
Q2 24
$84.5M
$11.0M
Q1 24
$118.8M
$11.5M
Stockholders' Equity
AGIO
AGIO
HHS
HHS
Q4 25
$1.2B
$20.5M
Q3 25
$1.3B
$19.9M
Q2 25
$1.4B
$22.2M
Q1 25
$1.5B
$21.4M
Q4 24
$1.5B
$21.7M
Q3 24
$1.6B
$21.0M
Q2 24
$660.5M
$20.6M
Q1 24
$743.9M
$20.0M
Total Assets
AGIO
AGIO
HHS
HHS
Q4 25
$1.3B
$91.8M
Q3 25
$1.4B
$92.7M
Q2 25
$1.5B
$95.0M
Q1 25
$1.6B
$100.6M
Q4 24
$1.7B
$101.8M
Q3 24
$1.8B
$108.1M
Q2 24
$773.1M
$109.7M
Q1 24
$849.7M
$113.4M

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
AGIO
AGIO
HHS
HHS
Operating Cash FlowLast quarter
$-96.2M
$737.0K
Free Cash FlowOCF − Capex
$-97.3M
$-686.0K
FCF MarginFCF / Revenue
-487.5%
-1.7%
Capex IntensityCapex / Revenue
5.6%
3.6%
Cash ConversionOCF / Net Profit
0.33×
TTM Free Cash FlowTrailing 4 quarters
$-377.3M
$-4.5M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
AGIO
AGIO
HHS
HHS
Q4 25
$-96.2M
$737.0K
Q3 25
$-88.2M
$3.2M
Q2 25
$-77.1M
$-4.8M
Q1 25
$-111.5M
$-818.0K
Q4 24
$-133.2M
$4.0M
Q3 24
$-84.2M
$-2.9M
Q2 24
$-72.6M
$1.6M
Q1 24
$-99.9M
$-5.7M
Free Cash Flow
AGIO
AGIO
HHS
HHS
Q4 25
$-97.3M
$-686.0K
Q3 25
$-89.7M
$2.2M
Q2 25
$-78.0M
$-5.1M
Q1 25
$-112.3M
$-923.0K
Q4 24
$-134.1M
$3.4M
Q3 24
$-84.6M
$-4.9M
Q2 24
$-72.7M
$926.0K
Q1 24
$-100.0M
$-6.2M
FCF Margin
AGIO
AGIO
HHS
HHS
Q4 25
-487.5%
-1.7%
Q3 25
-696.5%
5.5%
Q2 25
-626.2%
-13.1%
Q1 25
-1286.4%
-2.2%
Q4 24
-1250.1%
7.3%
Q3 24
-944.2%
-10.2%
Q2 24
-844.4%
2.1%
Q1 24
-1221.2%
-13.7%
Capex Intensity
AGIO
AGIO
HHS
HHS
Q4 25
5.6%
3.6%
Q3 25
12.1%
2.5%
Q2 25
7.0%
0.6%
Q1 25
8.8%
0.3%
Q4 24
9.0%
1.3%
Q3 24
4.7%
4.0%
Q2 24
1.8%
1.5%
Q1 24
1.7%
1.2%
Cash Conversion
AGIO
AGIO
HHS
HHS
Q4 25
0.33×
Q3 25
Q2 25
Q1 25
Q4 24
Q3 24
-0.09×
-20.76×
Q2 24
Q1 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

AGIO
AGIO

Segment breakdown not available.

HHS
HHS

Fulfillment And Logistics Services$17.3M43%
Customer Care$13.7M34%
Other$8.9M22%

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