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Side-by-side financial comparison of AGIOS PHARMACEUTICALS, INC. (AGIO) and i-80 Gold Corp. (IAUX). Click either name above to swap in a different company.
i-80 Gold Corp. is the larger business by last-quarter revenue ($21.3M vs $20.0M, roughly 1.1× AGIOS PHARMACEUTICALS, INC.). i-80 Gold Corp. runs the higher net margin — -401.9% vs -541.1%, a 139.2% gap on every dollar of revenue. i-80 Gold Corp. produced more free cash flow last quarter ($-39.2M vs $-97.3M).
Agios Pharmaceuticals Inc. is a publicly trading American pharmaceutical company pioneering therapies for genetically defined diseases, with a near-term focus on developing therapies for hemolytic anemias. The company was founded in 2008 by Lewis Cantley, Tak Mak and Craig Thompson. Agios is a Delaware corporation headquartered in Cambridge, Massachusetts. The company tendered an initial public offering in July 2013.
i-80 Gold Corp is a mineral exploration and development firm focused on gold and silver asset operations in Nevada, US. It advances high-potential mining projects, using responsible extraction practices to deliver precious metals to global industrial and investment markets.
AGIO vs IAUX — Head-to-Head
Income Statement — Q4 FY2025 vs Q4 FY2025
| Metric | | |
|---|---|---|
| Revenue | $20.0M | $21.3M |
| Net Profit | $-108.0M | $-85.6M |
| Gross Margin | 90.6% | 22.0% |
| Operating Margin | -608.9% | -291.6% |
| Net Margin | -541.1% | -401.9% |
| Revenue YoY | 86.1% | — |
| Net Profit YoY | -11.9% | — |
| EPS (diluted) | $-1.86 | $-0.10 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q4 25 | $20.0M | $21.3M | ||
| Q3 25 | $12.9M | $32.0M | ||
| Q2 25 | $12.5M | $27.8M | ||
| Q1 25 | $8.7M | $14.0M | ||
| Q4 24 | $10.7M | — | ||
| Q3 24 | $9.0M | $11.5M | ||
| Q2 24 | $8.6M | $7.2M | ||
| Q1 24 | $8.2M | — |
| Q4 25 | $-108.0M | $-85.6M | ||
| Q3 25 | $-103.4M | $-41.9M | ||
| Q2 25 | $-112.0M | $-30.2M | ||
| Q1 25 | $-89.3M | $-41.2M | ||
| Q4 24 | $-96.5M | — | ||
| Q3 24 | $947.9M | $-43.1M | ||
| Q2 24 | $-96.1M | $-41.0M | ||
| Q1 24 | $-81.5M | — |
| Q4 25 | 90.6% | 22.0% | ||
| Q3 25 | 87.0% | 9.7% | ||
| Q2 25 | 86.3% | 2.9% | ||
| Q1 25 | 87.6% | 20.7% | ||
| Q4 24 | 88.3% | — | ||
| Q3 24 | 91.3% | -42.7% | ||
| Q2 24 | 82.6% | -171.4% | ||
| Q1 24 | 92.3% | — |
| Q4 25 | -608.9% | -291.6% | ||
| Q3 25 | -907.4% | -86.7% | ||
| Q2 25 | -1020.1% | -67.4% | ||
| Q1 25 | -1222.0% | -112.3% | ||
| Q4 24 | -1165.3% | — | ||
| Q3 24 | -1146.9% | -210.0% | ||
| Q2 24 | -1228.3% | -435.2% | ||
| Q1 24 | -1124.3% | — |
| Q4 25 | -541.1% | -401.9% | ||
| Q3 25 | -803.1% | -130.8% | ||
| Q2 25 | -899.4% | -108.5% | ||
| Q1 25 | -1023.3% | -293.3% | ||
| Q4 24 | -899.6% | — | ||
| Q3 24 | 10574.7% | -374.5% | ||
| Q2 24 | -1115.7% | -570.8% | ||
| Q1 24 | -995.8% | — |
| Q4 25 | $-1.86 | $-0.10 | ||
| Q3 25 | $-1.78 | $-0.05 | ||
| Q2 25 | $-1.93 | $-0.05 | ||
| Q1 25 | $-1.55 | $-0.10 | ||
| Q4 24 | $-1.44 | — | ||
| Q3 24 | $16.22 | $-0.11 | ||
| Q2 24 | $-1.69 | $-0.11 | ||
| Q1 24 | $-1.45 | — |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $89.1M | $63.2M |
| Total DebtLower is stronger | — | $174.7M |
| Stockholders' EquityBook value | $1.2B | $346.8M |
| Total Assets | $1.3B | $703.4M |
| Debt / EquityLower = less leverage | — | 0.50× |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $89.1M | $63.2M | ||
| Q3 25 | $92.7M | $102.9M | ||
| Q2 25 | $80.9M | $133.7M | ||
| Q1 25 | $79.0M | $13.5M | ||
| Q4 24 | $76.2M | — | ||
| Q3 24 | $253.7M | $21.8M | ||
| Q2 24 | $84.5M | $47.8M | ||
| Q1 24 | $118.8M | — |
| Q4 25 | — | $174.7M | ||
| Q3 25 | — | $175.9M | ||
| Q2 25 | — | $175.8M | ||
| Q1 25 | — | $197.5M | ||
| Q4 24 | — | — | ||
| Q3 24 | — | — | ||
| Q2 24 | — | — | ||
| Q1 24 | — | — |
| Q4 25 | $1.2B | $346.8M | ||
| Q3 25 | $1.3B | $423.0M | ||
| Q2 25 | $1.4B | $463.5M | ||
| Q1 25 | $1.5B | $318.0M | ||
| Q4 24 | $1.5B | — | ||
| Q3 24 | $1.6B | $346.9M | ||
| Q2 24 | $660.5M | $377.2M | ||
| Q1 24 | $743.9M | — |
| Q4 25 | $1.3B | $703.4M | ||
| Q3 25 | $1.4B | $756.2M | ||
| Q2 25 | $1.5B | $782.9M | ||
| Q1 25 | $1.6B | $659.0M | ||
| Q4 24 | $1.7B | — | ||
| Q3 24 | $1.8B | — | ||
| Q2 24 | $773.1M | — | ||
| Q1 24 | $849.7M | — |
| Q4 25 | — | 0.50× | ||
| Q3 25 | — | 0.42× | ||
| Q2 25 | — | 0.38× | ||
| Q1 25 | — | 0.62× | ||
| Q4 24 | — | — | ||
| Q3 24 | — | — | ||
| Q2 24 | — | — | ||
| Q1 24 | — | — |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | $-96.2M | $-34.3M |
| Free Cash FlowOCF − Capex | $-97.3M | $-39.2M |
| FCF MarginFCF / Revenue | -487.5% | -184.3% |
| Capex IntensityCapex / Revenue | 5.6% | 23.1% |
| Cash ConversionOCF / Net Profit | — | — |
| TTM Free Cash FlowTrailing 4 quarters | $-377.3M | $-93.2M |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $-96.2M | $-34.3M | ||
| Q3 25 | $-88.2M | $-15.2M | ||
| Q2 25 | $-77.1M | $-11.3M | ||
| Q1 25 | $-111.5M | $-22.7M | ||
| Q4 24 | $-133.2M | — | ||
| Q3 24 | $-84.2M | $-23.5M | ||
| Q2 24 | $-72.6M | $-24.6M | ||
| Q1 24 | $-99.9M | — |
| Q4 25 | $-97.3M | $-39.2M | ||
| Q3 25 | $-89.7M | $-18.5M | ||
| Q2 25 | $-78.0M | $-12.4M | ||
| Q1 25 | $-112.3M | $-23.1M | ||
| Q4 24 | $-134.1M | — | ||
| Q3 24 | $-84.6M | $-23.8M | ||
| Q2 24 | $-72.7M | $-25.1M | ||
| Q1 24 | $-100.0M | — |
| Q4 25 | -487.5% | -184.3% | ||
| Q3 25 | -696.5% | -57.8% | ||
| Q2 25 | -626.2% | -44.7% | ||
| Q1 25 | -1286.4% | -164.1% | ||
| Q4 24 | -1250.1% | — | ||
| Q3 24 | -944.2% | -206.7% | ||
| Q2 24 | -844.4% | -349.1% | ||
| Q1 24 | -1221.2% | — |
| Q4 25 | 5.6% | 23.1% | ||
| Q3 25 | 12.1% | 10.2% | ||
| Q2 25 | 7.0% | 3.9% | ||
| Q1 25 | 8.8% | 2.5% | ||
| Q4 24 | 9.0% | — | ||
| Q3 24 | 4.7% | 2.5% | ||
| Q2 24 | 1.8% | 7.3% | ||
| Q1 24 | 1.7% | — |
| Q4 25 | — | — | ||
| Q3 25 | — | — | ||
| Q2 25 | — | — | ||
| Q1 25 | — | — | ||
| Q4 24 | — | — | ||
| Q3 24 | -0.09× | — | ||
| Q2 24 | — | — | ||
| Q1 24 | — | — |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
Revenue Breakdown by Segment
AGIO
Segment breakdown not available.
IAUX
| Granite Creek Mining Company | $20.3M | 95% |
| Ruby Hill Mining Company LLC | $991.0K | 5% |
| Lone Tree Minning Company | $3.0K | 0% |
