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Side-by-side financial comparison of AGIOS PHARMACEUTICALS, INC. (AGIO) and Orion Properties Inc. (ONL). Click either name above to swap in a different company.
Orion Properties Inc. is the larger business by last-quarter revenue ($36.3M vs $20.0M, roughly 1.8× AGIOS PHARMACEUTICALS, INC.). Orion Properties Inc. runs the higher net margin — -37.4% vs -541.1%, a 503.7% gap on every dollar of revenue. On growth, AGIOS PHARMACEUTICALS, INC. posted the faster year-over-year revenue change (86.1% vs -4.6%). Over the past eight quarters, AGIOS PHARMACEUTICALS, INC.'s revenue compounded faster (56.1% CAGR vs -4.9%).
Agios Pharmaceuticals Inc. is a publicly trading American pharmaceutical company pioneering therapies for genetically defined diseases, with a near-term focus on developing therapies for hemolytic anemias. The company was founded in 2008 by Lewis Cantley, Tak Mak and Craig Thompson. Agios is a Delaware corporation headquartered in Cambridge, Massachusetts. The company tendered an initial public offering in July 2013.
AGIO vs ONL — Head-to-Head
Income Statement — Q4 FY2025 vs Q1 FY2026
| Metric | | |
|---|---|---|
| Revenue | $20.0M | $36.3M |
| Net Profit | $-108.0M | $-13.6M |
| Gross Margin | 90.6% | — |
| Operating Margin | -608.9% | -9.3% |
| Net Margin | -541.1% | -37.4% |
| Revenue YoY | 86.1% | -4.6% |
| Net Profit YoY | -11.9% | -45.0% |
| EPS (diluted) | $-1.86 | $-0.24 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q1 26 | — | $36.3M | ||
| Q4 25 | $20.0M | $35.2M | ||
| Q3 25 | $12.9M | $37.1M | ||
| Q2 25 | $12.5M | $37.3M | ||
| Q1 25 | $8.7M | $38.0M | ||
| Q4 24 | $10.7M | $38.4M | ||
| Q3 24 | $9.0M | $39.2M | ||
| Q2 24 | $8.6M | $40.1M |
| Q1 26 | — | $-13.6M | ||
| Q4 25 | $-108.0M | $-35.8M | ||
| Q3 25 | $-103.4M | $-69.0M | ||
| Q2 25 | $-112.0M | $-25.1M | ||
| Q1 25 | $-89.3M | $-9.4M | ||
| Q4 24 | $-96.5M | $-32.8M | ||
| Q3 24 | $947.9M | $-10.2M | ||
| Q2 24 | $-96.1M | $-33.8M |
| Q1 26 | — | — | ||
| Q4 25 | 90.6% | — | ||
| Q3 25 | 87.0% | — | ||
| Q2 25 | 86.3% | — | ||
| Q1 25 | 87.6% | — | ||
| Q4 24 | 88.3% | — | ||
| Q3 24 | 91.3% | — | ||
| Q2 24 | 82.6% | — |
| Q1 26 | — | -9.3% | ||
| Q4 25 | -608.9% | -101.5% | ||
| Q3 25 | -907.4% | -185.8% | ||
| Q2 25 | -1020.1% | -67.1% | ||
| Q1 25 | -1222.0% | -24.4% | ||
| Q4 24 | -1165.3% | -85.4% | ||
| Q3 24 | -1146.9% | -25.9% | ||
| Q2 24 | -1228.3% | -84.1% |
| Q1 26 | — | -37.4% | ||
| Q4 25 | -541.1% | -101.7% | ||
| Q3 25 | -803.1% | -186.0% | ||
| Q2 25 | -899.4% | -67.3% | ||
| Q1 25 | -1023.3% | -24.6% | ||
| Q4 24 | -899.6% | -85.4% | ||
| Q3 24 | 10574.7% | -26.1% | ||
| Q2 24 | -1115.7% | -84.2% |
| Q1 26 | — | $-0.24 | ||
| Q4 25 | $-1.86 | $-0.63 | ||
| Q3 25 | $-1.78 | $-1.23 | ||
| Q2 25 | $-1.93 | $-0.45 | ||
| Q1 25 | $-1.55 | $-0.17 | ||
| Q4 24 | $-1.44 | $-0.59 | ||
| Q3 24 | $16.22 | $-0.18 | ||
| Q2 24 | $-1.69 | $-0.60 |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $89.1M | $10.3M |
| Total DebtLower is stronger | — | — |
| Stockholders' EquityBook value | $1.2B | $608.5M |
| Total Assets | $1.3B | $1.2B |
| Debt / EquityLower = less leverage | — | — |
8-quarter trend — quarters aligned by calendar period.
| Q1 26 | — | $10.3M | ||
| Q4 25 | $89.1M | $22.4M | ||
| Q3 25 | $92.7M | $32.6M | ||
| Q2 25 | $80.9M | $17.4M | ||
| Q1 25 | $79.0M | $9.4M | ||
| Q4 24 | $76.2M | $15.6M | ||
| Q3 24 | $253.7M | $16.6M | ||
| Q2 24 | $84.5M | $24.2M |
| Q1 26 | — | — | ||
| Q4 25 | — | $465.0M | ||
| Q3 25 | — | $483.0M | ||
| Q2 25 | — | $483.0M | ||
| Q1 25 | — | $505.0M | ||
| Q4 24 | — | $492.0M | ||
| Q3 24 | — | $485.0M | ||
| Q2 24 | — | $462.0M |
| Q1 26 | — | $608.5M | ||
| Q4 25 | $1.2B | $623.2M | ||
| Q3 25 | $1.3B | $658.8M | ||
| Q2 25 | $1.4B | $728.0M | ||
| Q1 25 | $1.5B | $753.5M | ||
| Q4 24 | $1.5B | $763.9M | ||
| Q3 24 | $1.6B | $800.9M | ||
| Q2 24 | $660.5M | $816.1M |
| Q1 26 | — | $1.2B | ||
| Q4 25 | $1.3B | $1.2B | ||
| Q3 25 | $1.4B | $1.2B | ||
| Q2 25 | $1.5B | $1.3B | ||
| Q1 25 | $1.6B | $1.3B | ||
| Q4 24 | $1.7B | $1.3B | ||
| Q3 24 | $1.8B | $1.4B | ||
| Q2 24 | $773.1M | $1.3B |
| Q1 26 | — | — | ||
| Q4 25 | — | 0.75× | ||
| Q3 25 | — | 0.73× | ||
| Q2 25 | — | 0.66× | ||
| Q1 25 | — | 0.67× | ||
| Q4 24 | — | 0.64× | ||
| Q3 24 | — | 0.61× | ||
| Q2 24 | — | 0.57× |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | $-96.2M | — |
| Free Cash FlowOCF − Capex | $-97.3M | — |
| FCF MarginFCF / Revenue | -487.5% | — |
| Capex IntensityCapex / Revenue | 5.6% | 51.4% |
| Cash ConversionOCF / Net Profit | — | — |
| TTM Free Cash FlowTrailing 4 quarters | $-377.3M | — |
8-quarter trend — quarters aligned by calendar period.
| Q1 26 | — | — | ||
| Q4 25 | $-96.2M | $23.6M | ||
| Q3 25 | $-88.2M | $5.7M | ||
| Q2 25 | $-77.1M | $11.6M | ||
| Q1 25 | $-111.5M | $-2.2M | ||
| Q4 24 | $-133.2M | $54.3M | ||
| Q3 24 | $-84.2M | $13.8M | ||
| Q2 24 | $-72.6M | $17.0M |
| Q1 26 | — | — | ||
| Q4 25 | $-97.3M | — | ||
| Q3 25 | $-89.7M | — | ||
| Q2 25 | $-78.0M | — | ||
| Q1 25 | $-112.3M | — | ||
| Q4 24 | $-134.1M | — | ||
| Q3 24 | $-84.6M | — | ||
| Q2 24 | $-72.7M | — |
| Q1 26 | — | — | ||
| Q4 25 | -487.5% | — | ||
| Q3 25 | -696.5% | — | ||
| Q2 25 | -626.2% | — | ||
| Q1 25 | -1286.4% | — | ||
| Q4 24 | -1250.1% | — | ||
| Q3 24 | -944.2% | — | ||
| Q2 24 | -844.4% | — |
| Q1 26 | — | 51.4% | ||
| Q4 25 | 5.6% | — | ||
| Q3 25 | 12.1% | — | ||
| Q2 25 | 7.0% | — | ||
| Q1 25 | 8.8% | — | ||
| Q4 24 | 9.0% | — | ||
| Q3 24 | 4.7% | — | ||
| Q2 24 | 1.8% | — |
| Q1 26 | — | — | ||
| Q4 25 | — | — | ||
| Q3 25 | — | — | ||
| Q2 25 | — | — | ||
| Q1 25 | — | — | ||
| Q4 24 | — | — | ||
| Q3 24 | -0.09× | — | ||
| Q2 24 | — | — |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
Revenue Breakdown by Segment
AGIO
Segment breakdown not available.
ONL
| Rental | $36.1M | 100% |
| Fee income from unconsolidated joint venture | $137.0K | 0% |
