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Side-by-side financial comparison of AGIOS PHARMACEUTICALS, INC. (AGIO) and Ponce Financial Group, Inc. (PDLB). Click either name above to swap in a different company.
Ponce Financial Group, Inc. is the larger business by last-quarter revenue ($31.4M vs $20.0M, roughly 1.6× AGIOS PHARMACEUTICALS, INC.). Ponce Financial Group, Inc. runs the higher net margin — 36.3% vs -541.1%, a 577.4% gap on every dollar of revenue. On growth, AGIOS PHARMACEUTICALS, INC. posted the faster year-over-year revenue change (86.1% vs 37.6%). Ponce Financial Group, Inc. produced more free cash flow last quarter ($54.6M vs $-97.3M). Over the past eight quarters, AGIOS PHARMACEUTICALS, INC.'s revenue compounded faster (56.1% CAGR vs 23.7%).
Agios Pharmaceuticals Inc. is a publicly trading American pharmaceutical company pioneering therapies for genetically defined diseases, with a near-term focus on developing therapies for hemolytic anemias. The company was founded in 2008 by Lewis Cantley, Tak Mak and Craig Thompson. Agios is a Delaware corporation headquartered in Cambridge, Massachusetts. The company tendered an initial public offering in July 2013.
Ponce Financial Group, Inc. is a U.S.-based financial holding company operating Ponce Bank as its core subsidiary. It serves multicultural, immigrant and low-to-moderate income communities in the New York metro area, offering retail and commercial banking products including deposits, mortgages, small business financing and personal credit.
AGIO vs PDLB — Head-to-Head
Income Statement — Q4 FY2025 vs Q4 FY2025
| Metric | | |
|---|---|---|
| Revenue | $20.0M | $31.4M |
| Net Profit | $-108.0M | $10.1M |
| Gross Margin | 90.6% | — |
| Operating Margin | -608.9% | 43.6% |
| Net Margin | -541.1% | 36.3% |
| Revenue YoY | 86.1% | 37.6% |
| Net Profit YoY | -11.9% | 245.6% |
| EPS (diluted) | $-1.86 | $0.43 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q4 25 | $20.0M | $31.4M | ||
| Q3 25 | $12.9M | $26.7M | ||
| Q2 25 | $12.5M | $26.5M | ||
| Q1 25 | $8.7M | $24.6M | ||
| Q4 24 | $10.7M | $22.8M | ||
| Q3 24 | $9.0M | $20.2M | ||
| Q2 24 | $8.6M | $20.2M | ||
| Q1 24 | $8.2M | $20.5M |
| Q4 25 | $-108.0M | $10.1M | ||
| Q3 25 | $-103.4M | $6.5M | ||
| Q2 25 | $-112.0M | $6.1M | ||
| Q1 25 | $-89.3M | $6.0M | ||
| Q4 24 | $-96.5M | $2.9M | ||
| Q3 24 | $947.9M | $2.4M | ||
| Q2 24 | $-96.1M | $3.2M | ||
| Q1 24 | $-81.5M | $2.4M |
| Q4 25 | 90.6% | — | ||
| Q3 25 | 87.0% | — | ||
| Q2 25 | 86.3% | — | ||
| Q1 25 | 87.6% | — | ||
| Q4 24 | 88.3% | — | ||
| Q3 24 | 91.3% | — | ||
| Q2 24 | 82.6% | — | ||
| Q1 24 | 92.3% | — |
| Q4 25 | -608.9% | 43.6% | ||
| Q3 25 | -907.4% | 32.8% | ||
| Q2 25 | -1020.1% | 30.2% | ||
| Q1 25 | -1222.0% | 32.5% | ||
| Q4 24 | -1165.3% | 19.6% | ||
| Q3 24 | -1146.9% | 15.2% | ||
| Q2 24 | -1228.3% | 21.8% | ||
| Q1 24 | -1124.3% | 18.3% |
| Q4 25 | -541.1% | 36.3% | ||
| Q3 25 | -803.1% | 24.3% | ||
| Q2 25 | -899.4% | 23.0% | ||
| Q1 25 | -1023.3% | 24.2% | ||
| Q4 24 | -899.6% | 14.1% | ||
| Q3 24 | 10574.7% | 12.1% | ||
| Q2 24 | -1115.7% | 15.8% | ||
| Q1 24 | -995.8% | 11.8% |
| Q4 25 | $-1.86 | $0.43 | ||
| Q3 25 | $-1.78 | $0.27 | ||
| Q2 25 | $-1.93 | $0.25 | ||
| Q1 25 | $-1.55 | $0.25 | ||
| Q4 24 | $-1.44 | $0.11 | ||
| Q3 24 | $16.22 | $0.10 | ||
| Q2 24 | $-1.69 | $0.14 | ||
| Q1 24 | $-1.45 | $0.11 |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $89.1M | $126.2M |
| Total DebtLower is stronger | — | $596.1M |
| Stockholders' EquityBook value | $1.2B | $541.5M |
| Total Assets | $1.3B | $3.2B |
| Debt / EquityLower = less leverage | — | 1.10× |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $89.1M | $126.2M | ||
| Q3 25 | $92.7M | $146.6M | ||
| Q2 25 | $80.9M | $126.6M | ||
| Q1 25 | $79.0M | $129.9M | ||
| Q4 24 | $76.2M | $139.8M | ||
| Q3 24 | $253.7M | $155.8M | ||
| Q2 24 | $84.5M | $103.2M | ||
| Q1 24 | $118.8M | $134.7M |
| Q4 25 | — | $596.1M | ||
| Q3 25 | — | $521.1M | ||
| Q2 25 | — | $536.1M | ||
| Q1 25 | — | $521.1M | ||
| Q4 24 | — | $596.1M | ||
| Q3 24 | — | $580.4M | ||
| Q2 24 | — | $680.4M | ||
| Q1 24 | — | $680.4M |
| Q4 25 | $1.2B | $541.5M | ||
| Q3 25 | $1.3B | $529.8M | ||
| Q2 25 | $1.4B | $521.1M | ||
| Q1 25 | $1.5B | $513.9M | ||
| Q4 24 | $1.5B | $505.5M | ||
| Q3 24 | $1.6B | $504.6M | ||
| Q2 24 | $660.5M | $497.7M | ||
| Q1 24 | $743.9M | $493.7M |
| Q4 25 | $1.3B | $3.2B | ||
| Q3 25 | $1.4B | $3.2B | ||
| Q2 25 | $1.5B | $3.2B | ||
| Q1 25 | $1.6B | $3.1B | ||
| Q4 24 | $1.7B | $3.0B | ||
| Q3 24 | $1.8B | $3.0B | ||
| Q2 24 | $773.1M | $2.8B | ||
| Q1 24 | $849.7M | $2.8B |
| Q4 25 | — | 1.10× | ||
| Q3 25 | — | 0.98× | ||
| Q2 25 | — | 1.03× | ||
| Q1 25 | — | 1.01× | ||
| Q4 24 | — | 1.18× | ||
| Q3 24 | — | 1.15× | ||
| Q2 24 | — | 1.37× | ||
| Q1 24 | — | 1.38× |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | $-96.2M | $55.6M |
| Free Cash FlowOCF − Capex | $-97.3M | $54.6M |
| FCF MarginFCF / Revenue | -487.5% | 173.9% |
| Capex IntensityCapex / Revenue | 5.6% | 3.1% |
| Cash ConversionOCF / Net Profit | — | 5.48× |
| TTM Free Cash FlowTrailing 4 quarters | $-377.3M | $74.3M |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $-96.2M | $55.6M | ||
| Q3 25 | $-88.2M | $1.4M | ||
| Q2 25 | $-77.1M | $6.2M | ||
| Q1 25 | $-111.5M | $13.1M | ||
| Q4 24 | $-133.2M | $7.2M | ||
| Q3 24 | $-84.2M | $-14.6M | ||
| Q2 24 | $-72.6M | $-2.6M | ||
| Q1 24 | $-99.9M | $1.5M |
| Q4 25 | $-97.3M | $54.6M | ||
| Q3 25 | $-89.7M | $786.0K | ||
| Q2 25 | $-78.0M | $5.9M | ||
| Q1 25 | $-112.3M | $12.9M | ||
| Q4 24 | $-134.1M | $4.5M | ||
| Q3 24 | $-84.6M | $-15.0M | ||
| Q2 24 | $-72.7M | $-2.6M | ||
| Q1 24 | $-100.0M | $-315.0K |
| Q4 25 | -487.5% | 173.9% | ||
| Q3 25 | -696.5% | 2.9% | ||
| Q2 25 | -626.2% | 22.4% | ||
| Q1 25 | -1286.4% | 52.6% | ||
| Q4 24 | -1250.1% | 19.7% | ||
| Q3 24 | -944.2% | -74.1% | ||
| Q2 24 | -844.4% | -13.0% | ||
| Q1 24 | -1221.2% | -1.5% |
| Q4 25 | 5.6% | 3.1% | ||
| Q3 25 | 12.1% | 2.3% | ||
| Q2 25 | 7.0% | 1.0% | ||
| Q1 25 | 8.8% | 0.6% | ||
| Q4 24 | 9.0% | 11.9% | ||
| Q3 24 | 4.7% | 2.0% | ||
| Q2 24 | 1.8% | 0.3% | ||
| Q1 24 | 1.7% | 8.7% |
| Q4 25 | — | 5.48× | ||
| Q3 25 | — | 0.21× | ||
| Q2 25 | — | 1.01× | ||
| Q1 25 | — | 2.20× | ||
| Q4 24 | — | 2.46× | ||
| Q3 24 | -0.09× | -5.99× | ||
| Q2 24 | — | -0.80× | ||
| Q1 24 | — | 0.61× |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
