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Side-by-side financial comparison of AGIOS PHARMACEUTICALS, INC. (AGIO) and Alpine Income Property Trust, Inc. (PINE). Click either name above to swap in a different company.

AGIOS PHARMACEUTICALS, INC. is the larger business by last-quarter revenue ($20.0M vs $18.4M, roughly 1.1× Alpine Income Property Trust, Inc.). Alpine Income Property Trust, Inc. runs the higher net margin — 11.9% vs -541.1%, a 553.0% gap on every dollar of revenue. On growth, AGIOS PHARMACEUTICALS, INC. posted the faster year-over-year revenue change (86.1% vs 29.6%). Over the past eight quarters, AGIOS PHARMACEUTICALS, INC.'s revenue compounded faster (56.1% CAGR vs 21.4%).

Agios Pharmaceuticals Inc. is a publicly trading American pharmaceutical company pioneering therapies for genetically defined diseases, with a near-term focus on developing therapies for hemolytic anemias. The company was founded in 2008 by Lewis Cantley, Tak Mak and Craig Thompson. Agios is a Delaware corporation headquartered in Cambridge, Massachusetts. The company tendered an initial public offering in July 2013.

Alpine Income Property Trust, Inc. is a publicly traded real estate investment trust that owns and operates a diversified portfolio of single-tenant net lease commercial properties across the United States. Its core asset segments include essential retail, industrial, and suburban office spaces, delivering stable recurring rental revenue to support consistent returns for its shareholders.

AGIO vs PINE — Head-to-Head

Bigger by revenue
AGIO
AGIO
1.1× larger
AGIO
$20.0M
$18.4M
PINE
Growing faster (revenue YoY)
AGIO
AGIO
+56.5% gap
AGIO
86.1%
29.6%
PINE
Higher net margin
PINE
PINE
553.0% more per $
PINE
11.9%
-541.1%
AGIO
Faster 2-yr revenue CAGR
AGIO
AGIO
Annualised
AGIO
56.1%
21.4%
PINE

Income Statement — Q4 FY2025 vs Q1 FY2026

Metric
AGIO
AGIO
PINE
PINE
Revenue
$20.0M
$18.4M
Net Profit
$-108.0M
$2.2M
Gross Margin
90.6%
Operating Margin
-608.9%
35.4%
Net Margin
-541.1%
11.9%
Revenue YoY
86.1%
29.6%
Net Profit YoY
-11.9%
285.3%
EPS (diluted)
$-1.86
$0.06

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
AGIO
AGIO
PINE
PINE
Q1 26
$18.4M
Q4 25
$20.0M
$16.9M
Q3 25
$12.9M
$14.6M
Q2 25
$12.5M
$14.9M
Q1 25
$8.7M
$14.2M
Q4 24
$10.7M
$13.8M
Q3 24
$9.0M
$13.5M
Q2 24
$8.6M
$12.5M
Net Profit
AGIO
AGIO
PINE
PINE
Q1 26
$2.2M
Q4 25
$-108.0M
$1.5M
Q3 25
$-103.4M
$-1.3M
Q2 25
$-112.0M
$-1.6M
Q1 25
$-89.3M
$-1.2M
Q4 24
$-96.5M
$-958.0K
Q3 24
$947.9M
$3.1M
Q2 24
$-96.1M
$204.0K
Gross Margin
AGIO
AGIO
PINE
PINE
Q1 26
Q4 25
90.6%
Q3 25
87.0%
Q2 25
86.3%
Q1 25
87.6%
Q4 24
88.3%
Q3 24
91.3%
Q2 24
82.6%
Operating Margin
AGIO
AGIO
PINE
PINE
Q1 26
35.4%
Q4 25
-608.9%
35.3%
Q3 25
-907.4%
16.6%
Q2 25
-1020.1%
16.8%
Q1 25
-1222.0%
16.0%
Q4 24
-1165.3%
14.3%
Q3 24
-1146.9%
47.9%
Q2 24
-1228.3%
24.0%
Net Margin
AGIO
AGIO
PINE
PINE
Q1 26
11.9%
Q4 25
-541.1%
8.7%
Q3 25
-803.1%
-9.0%
Q2 25
-899.4%
-11.0%
Q1 25
-1023.3%
-8.3%
Q4 24
-899.6%
-6.9%
Q3 24
10574.7%
22.8%
Q2 24
-1115.7%
1.6%
EPS (diluted)
AGIO
AGIO
PINE
PINE
Q1 26
$0.06
Q4 25
$-1.86
$0.07
Q3 25
$-1.78
$-0.09
Q2 25
$-1.93
$-0.12
Q1 25
$-1.55
$-0.08
Q4 24
$-1.44
$-0.06
Q3 24
$16.22
$0.21
Q2 24
$-1.69
$0.01

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
AGIO
AGIO
PINE
PINE
Cash + ST InvestmentsLiquidity on hand
$89.1M
$2.6M
Total DebtLower is stronger
Stockholders' EquityBook value
$1.2B
$312.5M
Total Assets
$1.3B
$745.1M
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
AGIO
AGIO
PINE
PINE
Q1 26
$2.6M
Q4 25
$89.1M
$4.6M
Q3 25
$92.7M
$1.2M
Q2 25
$80.9M
$5.0M
Q1 25
$79.0M
$6.1M
Q4 24
$76.2M
$1.6M
Q3 24
$253.7M
$2.6M
Q2 24
$84.5M
$3.3M
Total Debt
AGIO
AGIO
PINE
PINE
Q1 26
Q4 25
$377.7M
Q3 25
$358.2M
Q2 25
$352.6M
Q1 25
$356.5M
Q4 24
$301.5M
Q3 24
$278.9M
Q2 24
$268.3M
Stockholders' Equity
AGIO
AGIO
PINE
PINE
Q1 26
$312.5M
Q4 25
$1.2B
$279.9M
Q3 25
$1.3B
$223.5M
Q2 25
$1.4B
$229.8M
Q1 25
$1.5B
$240.9M
Q4 24
$1.5B
$253.0M
Q3 24
$1.6B
$248.2M
Q2 24
$660.5M
$244.0M
Total Assets
AGIO
AGIO
PINE
PINE
Q1 26
$745.1M
Q4 25
$1.3B
$715.9M
Q3 25
$1.4B
$621.4M
Q2 25
$1.5B
$628.4M
Q1 25
$1.6B
$647.4M
Q4 24
$1.7B
$605.0M
Q3 24
$1.8B
$579.0M
Q2 24
$773.1M
$565.8M
Debt / Equity
AGIO
AGIO
PINE
PINE
Q1 26
Q4 25
1.35×
Q3 25
1.60×
Q2 25
1.53×
Q1 25
1.48×
Q4 24
1.19×
Q3 24
1.12×
Q2 24
1.10×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
AGIO
AGIO
PINE
PINE
Operating Cash FlowLast quarter
$-96.2M
Free Cash FlowOCF − Capex
$-97.3M
FCF MarginFCF / Revenue
-487.5%
Capex IntensityCapex / Revenue
5.6%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$-377.3M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
AGIO
AGIO
PINE
PINE
Q1 26
Q4 25
$-96.2M
$25.8M
Q3 25
$-88.2M
$8.7M
Q2 25
$-77.1M
$9.1M
Q1 25
$-111.5M
$5.8M
Q4 24
$-133.2M
$23.4M
Q3 24
$-84.2M
$6.2M
Q2 24
$-72.6M
$8.0M
Free Cash Flow
AGIO
AGIO
PINE
PINE
Q1 26
Q4 25
$-97.3M
$-87.8M
Q3 25
$-89.7M
$-48.8M
Q2 25
$-78.0M
$-3.0M
Q1 25
$-112.3M
$-55.5M
Q4 24
$-134.1M
$-33.4M
Q3 24
$-84.6M
$-43.0M
Q2 24
$-72.7M
$-13.5M
FCF Margin
AGIO
AGIO
PINE
PINE
Q1 26
Q4 25
-487.5%
-519.4%
Q3 25
-696.5%
-334.9%
Q2 25
-626.2%
-20.0%
Q1 25
-1286.4%
-391.0%
Q4 24
-1250.1%
-242.4%
Q3 24
-944.2%
-319.3%
Q2 24
-844.4%
-108.0%
Capex Intensity
AGIO
AGIO
PINE
PINE
Q1 26
Q4 25
5.6%
671.8%
Q3 25
12.1%
394.8%
Q2 25
7.0%
81.2%
Q1 25
8.8%
432.0%
Q4 24
9.0%
412.3%
Q3 24
4.7%
365.4%
Q2 24
1.8%
172.3%
Cash Conversion
AGIO
AGIO
PINE
PINE
Q1 26
Q4 25
17.48×
Q3 25
Q2 25
Q1 25
Q4 24
Q3 24
-0.09×
2.02×
Q2 24
39.37×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

AGIO
AGIO

Segment breakdown not available.

PINE
PINE

Lease Income$12.6M68%
Other$5.8M31%
Other Revenue$46.0K0%

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