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Side-by-side financial comparison of AGIOS PHARMACEUTICALS, INC. (AGIO) and UNITED SECURITY BANCSHARES (UBFO). Click either name above to swap in a different company.
AGIOS PHARMACEUTICALS, INC. is the larger business by last-quarter revenue ($20.0M vs $13.5M, roughly 1.5× UNITED SECURITY BANCSHARES). UNITED SECURITY BANCSHARES runs the higher net margin — 25.2% vs -541.1%, a 566.3% gap on every dollar of revenue. On growth, AGIOS PHARMACEUTICALS, INC. posted the faster year-over-year revenue change (86.1% vs 13.6%). UNITED SECURITY BANCSHARES produced more free cash flow last quarter ($19.8M vs $-97.3M). Over the past eight quarters, AGIOS PHARMACEUTICALS, INC.'s revenue compounded faster (56.1% CAGR vs 3.0%).
Agios Pharmaceuticals Inc. is a publicly trading American pharmaceutical company pioneering therapies for genetically defined diseases, with a near-term focus on developing therapies for hemolytic anemias. The company was founded in 2008 by Lewis Cantley, Tak Mak and Craig Thompson. Agios is a Delaware corporation headquartered in Cambridge, Massachusetts. The company tendered an initial public offering in July 2013.
United Security Bancshares is a bank holding company headquartered in Fresno, California. It operates 11 branches.
AGIO vs UBFO — Head-to-Head
Income Statement — Q4 FY2025 vs Q4 FY2025
| Metric | | |
|---|---|---|
| Revenue | $20.0M | $13.5M |
| Net Profit | $-108.0M | $3.4M |
| Gross Margin | 90.6% | — |
| Operating Margin | -608.9% | 31.5% |
| Net Margin | -541.1% | 25.2% |
| Revenue YoY | 86.1% | 13.6% |
| Net Profit YoY | -11.9% | 36.8% |
| EPS (diluted) | $-1.86 | $0.18 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q4 25 | $20.0M | $13.5M | ||
| Q3 25 | $12.9M | $14.0M | ||
| Q2 25 | $12.5M | $12.6M | ||
| Q1 25 | $8.7M | $13.7M | ||
| Q4 24 | $10.7M | $11.9M | ||
| Q3 24 | $9.0M | $13.8M | ||
| Q2 24 | $8.6M | $13.0M | ||
| Q1 24 | $8.2M | $12.8M |
| Q4 25 | $-108.0M | $3.4M | ||
| Q3 25 | $-103.4M | $4.0M | ||
| Q2 25 | $-112.0M | $2.2M | ||
| Q1 25 | $-89.3M | $2.7M | ||
| Q4 24 | $-96.5M | $2.5M | ||
| Q3 24 | $947.9M | $3.8M | ||
| Q2 24 | $-96.1M | $4.3M | ||
| Q1 24 | $-81.5M | $4.2M |
| Q4 25 | 90.6% | — | ||
| Q3 25 | 87.0% | — | ||
| Q2 25 | 86.3% | — | ||
| Q1 25 | 87.6% | — | ||
| Q4 24 | 88.3% | — | ||
| Q3 24 | 91.3% | — | ||
| Q2 24 | 82.6% | — | ||
| Q1 24 | 92.3% | — |
| Q4 25 | -608.9% | 31.5% | ||
| Q3 25 | -907.4% | 40.3% | ||
| Q2 25 | -1020.1% | 24.0% | ||
| Q1 25 | -1222.0% | 27.5% | ||
| Q4 24 | -1165.3% | 27.5% | ||
| Q3 24 | -1146.9% | 37.1% | ||
| Q2 24 | -1228.3% | 46.4% | ||
| Q1 24 | -1124.3% | 45.9% |
| Q4 25 | -541.1% | 25.2% | ||
| Q3 25 | -803.1% | 28.7% | ||
| Q2 25 | -899.4% | 17.2% | ||
| Q1 25 | -1023.3% | 19.6% | ||
| Q4 24 | -899.6% | 20.9% | ||
| Q3 24 | 10574.7% | 27.7% | ||
| Q2 24 | -1115.7% | 33.0% | ||
| Q1 24 | -995.8% | 32.6% |
| Q4 25 | $-1.86 | $0.18 | ||
| Q3 25 | $-1.78 | $0.23 | ||
| Q2 25 | $-1.93 | $0.13 | ||
| Q1 25 | $-1.55 | $0.16 | ||
| Q4 24 | $-1.44 | $0.14 | ||
| Q3 24 | $16.22 | $0.22 | ||
| Q2 24 | $-1.69 | $0.25 | ||
| Q1 24 | $-1.45 | $0.24 |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $89.1M | $264.2M |
| Total DebtLower is stronger | — | — |
| Stockholders' EquityBook value | $1.2B | $139.7M |
| Total Assets | $1.3B | $1.2B |
| Debt / EquityLower = less leverage | — | — |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $89.1M | $264.2M | ||
| Q3 25 | $92.7M | $211.1M | ||
| Q2 25 | $80.9M | $199.5M | ||
| Q1 25 | $79.0M | $198.4M | ||
| Q4 24 | $76.2M | $216.9M | ||
| Q3 24 | $253.7M | $216.8M | ||
| Q2 24 | $84.5M | $166.3M | ||
| Q1 24 | $118.8M | $168.6M |
| Q4 25 | $1.2B | $139.7M | ||
| Q3 25 | $1.3B | $137.4M | ||
| Q2 25 | $1.4B | $134.3M | ||
| Q1 25 | $1.5B | $132.9M | ||
| Q4 24 | $1.5B | $130.4M | ||
| Q3 24 | $1.6B | $132.9M | ||
| Q2 24 | $660.5M | $127.3M | ||
| Q1 24 | $743.9M | $124.2M |
| Q4 25 | $1.3B | $1.2B | ||
| Q3 25 | $1.4B | $1.2B | ||
| Q2 25 | $1.5B | $1.2B | ||
| Q1 25 | $1.6B | $1.2B | ||
| Q4 24 | $1.7B | $1.2B | ||
| Q3 24 | $1.8B | $1.3B | ||
| Q2 24 | $773.1M | $1.2B | ||
| Q1 24 | $849.7M | $1.2B |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | $-96.2M | $22.1M |
| Free Cash FlowOCF − Capex | $-97.3M | $19.8M |
| FCF MarginFCF / Revenue | -487.5% | 146.0% |
| Capex IntensityCapex / Revenue | 5.6% | 16.8% |
| Cash ConversionOCF / Net Profit | — | 6.46× |
| TTM Free Cash FlowTrailing 4 quarters | $-377.3M | $36.9M |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $-96.2M | $22.1M | ||
| Q3 25 | $-88.2M | $7.0M | ||
| Q2 25 | $-77.1M | $8.7M | ||
| Q1 25 | $-111.5M | $3.0M | ||
| Q4 24 | $-133.2M | $19.6M | ||
| Q3 24 | $-84.2M | $5.4M | ||
| Q2 24 | $-72.6M | $2.3M | ||
| Q1 24 | $-99.9M | $7.4M |
| Q4 25 | $-97.3M | $19.8M | ||
| Q3 25 | $-89.7M | $6.1M | ||
| Q2 25 | $-78.0M | $8.1M | ||
| Q1 25 | $-112.3M | $2.9M | ||
| Q4 24 | $-134.1M | $18.6M | ||
| Q3 24 | $-84.6M | $5.3M | ||
| Q2 24 | $-72.7M | $2.0M | ||
| Q1 24 | $-100.0M | $7.0M |
| Q4 25 | -487.5% | 146.0% | ||
| Q3 25 | -696.5% | 43.7% | ||
| Q2 25 | -626.2% | 64.3% | ||
| Q1 25 | -1286.4% | 21.2% | ||
| Q4 24 | -1250.1% | 156.0% | ||
| Q3 24 | -944.2% | 38.1% | ||
| Q2 24 | -844.4% | 15.5% | ||
| Q1 24 | -1221.2% | 54.8% |
| Q4 25 | 5.6% | 16.8% | ||
| Q3 25 | 12.1% | 6.0% | ||
| Q2 25 | 7.0% | 4.6% | ||
| Q1 25 | 8.8% | 0.9% | ||
| Q4 24 | 9.0% | 8.7% | ||
| Q3 24 | 4.7% | 0.7% | ||
| Q2 24 | 1.8% | 2.2% | ||
| Q1 24 | 1.7% | 3.6% |
| Q4 25 | — | 6.46× | ||
| Q3 25 | — | 1.73× | ||
| Q2 25 | — | 4.01× | ||
| Q1 25 | — | 1.13× | ||
| Q4 24 | — | 7.87× | ||
| Q3 24 | -0.09× | 1.40× | ||
| Q2 24 | — | 0.54× | ||
| Q1 24 | — | 1.79× |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
