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Side-by-side financial comparison of AGIOS PHARMACEUTICALS, INC. (AGIO) and Ucommune International Ltd (UK). Click either name above to swap in a different company.

AGIOS PHARMACEUTICALS, INC. is the larger business by last-quarter revenue ($20.0M vs $16.4M, roughly 1.2× Ucommune International Ltd). Ucommune International Ltd runs the higher net margin — -42.2% vs -541.1%, a 498.9% gap on every dollar of revenue. On growth, AGIOS PHARMACEUTICALS, INC. posted the faster year-over-year revenue change (86.1% vs -56.1%). Ucommune International Ltd produced more free cash flow last quarter ($-892.0K vs $-97.3M).

Agios Pharmaceuticals Inc. is a publicly trading American pharmaceutical company pioneering therapies for genetically defined diseases, with a near-term focus on developing therapies for hemolytic anemias. The company was founded in 2008 by Lewis Cantley, Tak Mak and Craig Thompson. Agios is a Delaware corporation headquartered in Cambridge, Massachusetts. The company tendered an initial public offering in July 2013.

Ucommune International Ltd., formerly known as UrWork, is a Beijing-based co-working space provider founded in 2015 by Mao Daqing. It is now the second-largest co-working space provider after WeWork, with properties in three dozen cities around the world, including Shanghai, Singapore, Hong Kong and New York City. The company was valued at 1.8 billion US dollars in August 2018, making it the first domestic unicorn in the Chinese co-working space, but by November 2018, Ucommune had completed i...

AGIO vs UK — Head-to-Head

Bigger by revenue
AGIO
AGIO
1.2× larger
AGIO
$20.0M
$16.4M
UK
Growing faster (revenue YoY)
AGIO
AGIO
+142.2% gap
AGIO
86.1%
-56.1%
UK
Higher net margin
UK
UK
498.9% more per $
UK
-42.2%
-541.1%
AGIO
More free cash flow
UK
UK
$96.4M more FCF
UK
$-892.0K
$-97.3M
AGIO

Income Statement — Q4 FY2025 vs Q2 FY2024

Metric
AGIO
AGIO
UK
UK
Revenue
$20.0M
$16.4M
Net Profit
$-108.0M
$-6.9M
Gross Margin
90.6%
Operating Margin
-608.9%
-23.6%
Net Margin
-541.1%
-42.2%
Revenue YoY
86.1%
-56.1%
Net Profit YoY
-11.9%
-30.2%
EPS (diluted)
$-1.86
$-8.55

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
AGIO
AGIO
UK
UK
Q4 25
$20.0M
Q3 25
$12.9M
Q2 25
$12.5M
Q1 25
$8.7M
Q4 24
$10.7M
Q3 24
$9.0M
Q2 24
$8.6M
$16.4M
Q1 24
$8.2M
Net Profit
AGIO
AGIO
UK
UK
Q4 25
$-108.0M
Q3 25
$-103.4M
Q2 25
$-112.0M
Q1 25
$-89.3M
Q4 24
$-96.5M
Q3 24
$947.9M
Q2 24
$-96.1M
$-6.9M
Q1 24
$-81.5M
Gross Margin
AGIO
AGIO
UK
UK
Q4 25
90.6%
Q3 25
87.0%
Q2 25
86.3%
Q1 25
87.6%
Q4 24
88.3%
Q3 24
91.3%
Q2 24
82.6%
Q1 24
92.3%
Operating Margin
AGIO
AGIO
UK
UK
Q4 25
-608.9%
Q3 25
-907.4%
Q2 25
-1020.1%
Q1 25
-1222.0%
Q4 24
-1165.3%
Q3 24
-1146.9%
Q2 24
-1228.3%
-23.6%
Q1 24
-1124.3%
Net Margin
AGIO
AGIO
UK
UK
Q4 25
-541.1%
Q3 25
-803.1%
Q2 25
-899.4%
Q1 25
-1023.3%
Q4 24
-899.6%
Q3 24
10574.7%
Q2 24
-1115.7%
-42.2%
Q1 24
-995.8%
EPS (diluted)
AGIO
AGIO
UK
UK
Q4 25
$-1.86
Q3 25
$-1.78
Q2 25
$-1.93
Q1 25
$-1.55
Q4 24
$-1.44
Q3 24
$16.22
Q2 24
$-1.69
$-8.55
Q1 24
$-1.45

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
AGIO
AGIO
UK
UK
Cash + ST InvestmentsLiquidity on hand
$89.1M
$10.7M
Total DebtLower is stronger
Stockholders' EquityBook value
$1.2B
$4.7M
Total Assets
$1.3B
$68.0M
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
AGIO
AGIO
UK
UK
Q4 25
$89.1M
Q3 25
$92.7M
Q2 25
$80.9M
Q1 25
$79.0M
Q4 24
$76.2M
Q3 24
$253.7M
Q2 24
$84.5M
$10.7M
Q1 24
$118.8M
Stockholders' Equity
AGIO
AGIO
UK
UK
Q4 25
$1.2B
Q3 25
$1.3B
Q2 25
$1.4B
Q1 25
$1.5B
Q4 24
$1.5B
Q3 24
$1.6B
Q2 24
$660.5M
$4.7M
Q1 24
$743.9M
Total Assets
AGIO
AGIO
UK
UK
Q4 25
$1.3B
Q3 25
$1.4B
Q2 25
$1.5B
Q1 25
$1.6B
Q4 24
$1.7B
Q3 24
$1.8B
Q2 24
$773.1M
$68.0M
Q1 24
$849.7M

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
AGIO
AGIO
UK
UK
Operating Cash FlowLast quarter
$-96.2M
$-677.0K
Free Cash FlowOCF − Capex
$-97.3M
$-892.0K
FCF MarginFCF / Revenue
-487.5%
-5.5%
Capex IntensityCapex / Revenue
5.6%
1.3%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$-377.3M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
AGIO
AGIO
UK
UK
Q4 25
$-96.2M
Q3 25
$-88.2M
Q2 25
$-77.1M
Q1 25
$-111.5M
Q4 24
$-133.2M
Q3 24
$-84.2M
Q2 24
$-72.6M
$-677.0K
Q1 24
$-99.9M
Free Cash Flow
AGIO
AGIO
UK
UK
Q4 25
$-97.3M
Q3 25
$-89.7M
Q2 25
$-78.0M
Q1 25
$-112.3M
Q4 24
$-134.1M
Q3 24
$-84.6M
Q2 24
$-72.7M
$-892.0K
Q1 24
$-100.0M
FCF Margin
AGIO
AGIO
UK
UK
Q4 25
-487.5%
Q3 25
-696.5%
Q2 25
-626.2%
Q1 25
-1286.4%
Q4 24
-1250.1%
Q3 24
-944.2%
Q2 24
-844.4%
-5.5%
Q1 24
-1221.2%
Capex Intensity
AGIO
AGIO
UK
UK
Q4 25
5.6%
Q3 25
12.1%
Q2 25
7.0%
Q1 25
8.8%
Q4 24
9.0%
Q3 24
4.7%
Q2 24
1.8%
1.3%
Q1 24
1.7%
Cash Conversion
AGIO
AGIO
UK
UK
Q4 25
Q3 25
Q2 25
Q1 25
Q4 24
Q3 24
-0.09×
Q2 24
Q1 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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