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Side-by-side financial comparison of Aligos Therapeutics, Inc. (ALGS) and REPLIGEN CORP (RGEN). Click either name above to swap in a different company.

REPLIGEN CORP is the larger business by last-quarter revenue ($197.9M vs $169.0K, roughly 1171.1× Aligos Therapeutics, Inc.). REPLIGEN CORP runs the higher net margin — 6.7% vs -11763.9%, a 11770.6% gap on every dollar of revenue. On growth, REPLIGEN CORP posted the faster year-over-year revenue change (13.6% vs -72.1%). Over the past eight quarters, REPLIGEN CORP's revenue compounded faster (14.4% CAGR vs -50.7%).

Aligos Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on developing novel targeted therapies for prevalent liver diseases and viral infections. Its core pipeline includes candidates for chronic hepatitis B, non-alcoholic steatohepatitis, and other liver-related disorders, advancing R&D to serve unmet global patient needs.

Repligen Corporation is a global life sciences company devoted to the development and commercialization of innovative bioprocessing technologies and systems that enable efficiencies in the process of manufacturing biological drugs.2025 The company is based in Waltham, Massachusetts,2014 and was incorporated in Delaware in 1981. A public company, Repligen is listed on the NASDAQ exchange under the symbol RGEN. As of 2025, Repligen employs over 1,900 employees globally and serves primarily biop...

ALGS vs RGEN — Head-to-Head

Bigger by revenue
RGEN
RGEN
1171.1× larger
RGEN
$197.9M
$169.0K
ALGS
Growing faster (revenue YoY)
RGEN
RGEN
+85.8% gap
RGEN
13.6%
-72.1%
ALGS
Higher net margin
RGEN
RGEN
11770.6% more per $
RGEN
6.7%
-11763.9%
ALGS
Faster 2-yr revenue CAGR
RGEN
RGEN
Annualised
RGEN
14.4%
-50.7%
ALGS

Income Statement — Q4 2025 vs Q4 2025

Metric
ALGS
ALGS
RGEN
RGEN
Revenue
$169.0K
$197.9M
Net Profit
$-19.9M
$13.3M
Gross Margin
52.5%
Operating Margin
-12907.7%
9.0%
Net Margin
-11763.9%
6.7%
Revenue YoY
-72.1%
13.6%
Net Profit YoY
75.8%
143.9%
EPS (diluted)
$4.23
$0.24

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
ALGS
ALGS
RGEN
RGEN
Q4 25
$169.0K
$197.9M
Q3 25
$741.0K
$188.8M
Q2 25
$965.0K
$182.4M
Q1 25
$311.0K
$169.2M
Q4 24
$606.0K
$174.1M
Q3 24
$1.3M
$154.9M
Q2 24
$1.1M
$154.1M
Q1 24
$694.0K
$151.3M
Net Profit
ALGS
ALGS
RGEN
RGEN
Q4 25
$-19.9M
$13.3M
Q3 25
$-31.5M
$14.9M
Q2 25
$-15.9M
$14.9M
Q1 25
$43.1M
$5.8M
Q4 24
$-82.2M
$-30.3M
Q3 24
$-19.3M
$-654.0K
Q2 24
$5.1M
$3.3M
Q1 24
$-34.9M
$2.1M
Gross Margin
ALGS
ALGS
RGEN
RGEN
Q4 25
52.5%
Q3 25
53.2%
Q2 25
50.0%
Q1 25
53.6%
Q4 24
26.1%
Q3 24
50.0%
Q2 24
49.8%
Q1 24
49.5%
Operating Margin
ALGS
ALGS
RGEN
RGEN
Q4 25
-12907.7%
9.0%
Q3 25
-3827.4%
8.9%
Q2 25
-1924.0%
7.6%
Q1 25
-6187.5%
3.9%
Q4 24
-3393.2%
-17.7%
Q3 24
-1610.5%
-5.1%
Q2 24
-2489.5%
1.0%
Q1 24
-3176.7%
1.3%
Net Margin
ALGS
ALGS
RGEN
RGEN
Q4 25
-11763.9%
6.7%
Q3 25
-4256.0%
7.9%
Q2 25
-1643.8%
8.2%
Q1 25
13854.7%
3.4%
Q4 24
-13556.1%
-17.4%
Q3 24
-1540.7%
-0.4%
Q2 24
477.0%
2.2%
Q1 24
-5023.5%
1.4%
EPS (diluted)
ALGS
ALGS
RGEN
RGEN
Q4 25
$4.23
$0.24
Q3 25
$-3.04
$0.26
Q2 25
$-1.53
$0.26
Q1 25
$-2.11
$0.10
Q4 24
$-13.10
$-0.55
Q3 24
$-3.07
$-0.01
Q2 24
$0.81
$0.06
Q1 24
$-5.58
$0.04

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
ALGS
ALGS
RGEN
RGEN
Cash + ST InvestmentsLiquidity on hand
$77.8M
$767.6M
Total DebtLower is stronger
$542.2M
Stockholders' EquityBook value
$53.5M
$2.1B
Total Assets
$88.5M
$2.9B
Debt / EquityLower = less leverage
0.26×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
ALGS
ALGS
RGEN
RGEN
Q4 25
$77.8M
$767.6M
Q3 25
$99.1M
$748.7M
Q2 25
$122.9M
$708.9M
Q1 25
$137.9M
$697.2M
Q4 24
$56.9M
$757.4M
Q3 24
$74.9M
$784.0M
Q2 24
$94.5M
$809.1M
Q1 24
$112.7M
$780.6M
Total Debt
ALGS
ALGS
RGEN
RGEN
Q4 25
$542.2M
Q3 25
$537.9M
Q2 25
Q1 25
Q4 24
$525.6M
Q3 24
Q2 24
Q1 24
Stockholders' Equity
ALGS
ALGS
RGEN
RGEN
Q4 25
$53.5M
$2.1B
Q3 25
$71.8M
$2.1B
Q2 25
$101.9M
$2.1B
Q1 25
$116.4M
$2.0B
Q4 24
$-29.0M
$2.0B
Q3 24
$50.1M
$2.0B
Q2 24
$67.2M
$2.0B
Q1 24
$59.8M
$2.0B
Total Assets
ALGS
ALGS
RGEN
RGEN
Q4 25
$88.5M
$2.9B
Q3 25
$109.8M
$2.9B
Q2 25
$134.7M
$2.9B
Q1 25
$150.7M
$2.9B
Q4 24
$70.1M
$2.8B
Q3 24
$88.4M
$2.8B
Q2 24
$108.8M
$2.9B
Q1 24
$127.9M
$2.8B
Debt / Equity
ALGS
ALGS
RGEN
RGEN
Q4 25
0.26×
Q3 25
0.26×
Q2 25
Q1 25
Q4 24
0.27×
Q3 24
Q2 24
Q1 24

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
ALGS
ALGS
RGEN
RGEN
Operating Cash FlowLast quarter
$-21.7M
$25.7M
Free Cash FlowOCF − Capex
$17.6M
FCF MarginFCF / Revenue
8.9%
Capex IntensityCapex / Revenue
4.1%
Cash ConversionOCF / Net Profit
1.93×
TTM Free Cash FlowTrailing 4 quarters
$93.9M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
ALGS
ALGS
RGEN
RGEN
Q4 25
$-21.7M
$25.7M
Q3 25
$-24.3M
$48.1M
Q2 25
$-15.5M
$28.6M
Q1 25
$-20.9M
$15.0M
Q4 24
$-18.4M
$39.2M
Q3 24
$-20.1M
$49.3M
Q2 24
$-19.5M
$42.2M
Q1 24
$-22.7M
$44.7M
Free Cash Flow
ALGS
ALGS
RGEN
RGEN
Q4 25
$17.6M
Q3 25
$43.4M
Q2 25
$21.5M
Q1 25
$11.4M
Q4 24
$33.6M
Q3 24
$42.3M
Q2 24
$37.4M
Q1 24
$36.4M
FCF Margin
ALGS
ALGS
RGEN
RGEN
Q4 25
8.9%
Q3 25
23.0%
Q2 25
11.8%
Q1 25
6.8%
Q4 24
19.3%
Q3 24
27.3%
Q2 24
24.3%
Q1 24
24.0%
Capex Intensity
ALGS
ALGS
RGEN
RGEN
Q4 25
4.1%
Q3 25
2.5%
Q2 25
3.9%
Q1 25
2.1%
Q4 24
3.2%
Q3 24
4.5%
Q2 24
3.1%
Q1 24
5.5%
Cash Conversion
ALGS
ALGS
RGEN
RGEN
Q4 25
1.93×
Q3 25
3.23×
Q2 25
1.92×
Q1 25
-0.49×
2.57×
Q4 24
Q3 24
Q2 24
-3.85×
12.70×
Q1 24
21.35×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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