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Side-by-side financial comparison of Aligos Therapeutics, Inc. (ALGS) and Revolution Medicines, Inc. (RVMD). Click either name above to swap in a different company.

Over the past eight quarters, Aligos Therapeutics, Inc.'s revenue compounded faster (-50.7% CAGR vs -100.0%).

Aligos Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on developing novel targeted therapies for prevalent liver diseases and viral infections. Its core pipeline includes candidates for chronic hepatitis B, non-alcoholic steatohepatitis, and other liver-related disorders, advancing R&D to serve unmet global patient needs.

Tempus AI, Inc. is an American health technology company founded in 2015 by Eric Lefkofsky in Chicago, Illinois. It was established by Lefkofsky soon after his wife was diagnosed with breast cancer. Tempus uses data and artificial intelligence (AI) to create precision medicine services, including diagnostics, for oncology, cardiology, radiology, and depression. The company went public on the Nasdaq on June 14, 2024, under the ticker symbol "TEM."

ALGS vs RVMD — Head-to-Head

Bigger by revenue
ALGS
ALGS
Infinity× larger
ALGS
$169.0K
$0
RVMD
Faster 2-yr revenue CAGR
ALGS
ALGS
Annualised
ALGS
-50.7%
-100.0%
RVMD

Income Statement — Q4 2025 vs Q4 2024

Metric
ALGS
ALGS
RVMD
RVMD
Revenue
$169.0K
$0
Net Profit
$-19.9M
$-194.6M
Gross Margin
Operating Margin
-12907.7%
Net Margin
-11763.9%
Revenue YoY
-72.1%
Net Profit YoY
75.8%
-20.4%
EPS (diluted)
$4.23
$-1.13

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
ALGS
ALGS
RVMD
RVMD
Q4 25
$169.0K
Q3 25
$741.0K
Q2 25
$965.0K
Q1 25
$311.0K
Q4 24
$606.0K
$0
Q3 24
$1.3M
$0
Q2 24
$1.1M
$0
Q1 24
$694.0K
$0
Net Profit
ALGS
ALGS
RVMD
RVMD
Q4 25
$-19.9M
Q3 25
$-31.5M
Q2 25
$-15.9M
Q1 25
$43.1M
Q4 24
$-82.2M
$-194.6M
Q3 24
$-19.3M
$-156.3M
Q2 24
$5.1M
$-133.2M
Q1 24
$-34.9M
$-116.0M
Operating Margin
ALGS
ALGS
RVMD
RVMD
Q4 25
-12907.7%
Q3 25
-3827.4%
Q2 25
-1924.0%
Q1 25
-6187.5%
Q4 24
-3393.2%
Q3 24
-1610.5%
Q2 24
-2489.5%
Q1 24
-3176.7%
Net Margin
ALGS
ALGS
RVMD
RVMD
Q4 25
-11763.9%
Q3 25
-4256.0%
Q2 25
-1643.8%
Q1 25
13854.7%
Q4 24
-13556.1%
Q3 24
-1540.7%
Q2 24
477.0%
Q1 24
-5023.5%
EPS (diluted)
ALGS
ALGS
RVMD
RVMD
Q4 25
$4.23
Q3 25
$-3.04
Q2 25
$-1.53
Q1 25
$-2.11
Q4 24
$-13.10
$-1.13
Q3 24
$-3.07
$-0.94
Q2 24
$0.81
$-0.81
Q1 24
$-5.58
$-0.70

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
ALGS
ALGS
RVMD
RVMD
Cash + ST InvestmentsLiquidity on hand
$77.8M
$2.3B
Total DebtLower is stronger
Stockholders' EquityBook value
$53.5M
$2.3B
Total Assets
$88.5M
$2.6B
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
ALGS
ALGS
RVMD
RVMD
Q4 25
$77.8M
Q3 25
$99.1M
Q2 25
$122.9M
Q1 25
$137.9M
Q4 24
$56.9M
$2.3B
Q3 24
$74.9M
$1.5B
Q2 24
$94.5M
$1.6B
Q1 24
$112.7M
$1.7B
Stockholders' Equity
ALGS
ALGS
RVMD
RVMD
Q4 25
$53.5M
Q3 25
$71.8M
Q2 25
$101.9M
Q1 25
$116.4M
Q4 24
$-29.0M
$2.3B
Q3 24
$50.1M
$1.6B
Q2 24
$67.2M
$1.6B
Q1 24
$59.8M
$1.7B
Total Assets
ALGS
ALGS
RVMD
RVMD
Q4 25
$88.5M
Q3 25
$109.8M
Q2 25
$134.7M
Q1 25
$150.7M
Q4 24
$70.1M
$2.6B
Q3 24
$88.4M
$1.8B
Q2 24
$108.8M
$1.8B
Q1 24
$127.9M
$1.9B

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
ALGS
ALGS
RVMD
RVMD
Operating Cash FlowLast quarter
$-21.7M
$-138.3M
Free Cash FlowOCF − Capex
$-139.5M
FCF MarginFCF / Revenue
Capex IntensityCapex / Revenue
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$-567.7M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
ALGS
ALGS
RVMD
RVMD
Q4 25
$-21.7M
Q3 25
$-24.3M
Q2 25
$-15.5M
Q1 25
$-20.9M
Q4 24
$-18.4M
$-138.3M
Q3 24
$-20.1M
$-130.4M
Q2 24
$-19.5M
$-128.2M
Q1 24
$-22.7M
$-160.6M
Free Cash Flow
ALGS
ALGS
RVMD
RVMD
Q4 25
Q3 25
Q2 25
Q1 25
Q4 24
$-139.5M
Q3 24
$-133.9M
Q2 24
$-130.6M
Q1 24
$-163.7M
Cash Conversion
ALGS
ALGS
RVMD
RVMD
Q4 25
Q3 25
Q2 25
Q1 25
-0.49×
Q4 24
Q3 24
Q2 24
-3.85×
Q1 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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